Alliance Française contre les Maladies Parasitaires


Ding

Project Title : "Characterization of P. falciparum histone methyl transferases: biological role and possible targets for new intervention strategies"

Project PI : Artur Scherf Co-PI : Dominique Mazier

Thesis defense : 15/12/2016

Lab : Biology of Host-parasite Interactions, Pasteur Institute, Paris



Position after paraFrap training : Postdoctoral researcher in Artur Scherf Lab, Pasteur Institute, Paris - France

Publications :

Zanghi, G., S. S. Vembar, S. Baumgarten, S. Ding, J. Guizetti, J. M. Bryant, D. Mattei, A. T. R. Jensen, L. Renia, Y. S. Goh, R. Sauerwein, C. C. Hermsen, J. F. Franetich, M. Bordessoulles, O. Silvie, V. Soulard, O. Scatton, P. Chen, S. Mecheri, D. Mazier and A. Scherf (2018). "A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection." Cell Rep [8.3] 22(11): 2951-2963. [Pubmed]

Sindikubwabo, F., S. Ding, T. Hussain, P. Ortet, M. Barakat, S. Baumgarten, D. Cannella, A. Palencia, A. Bougdour, L. Belmudes, Y. Coute, I. Tardieux, C. Y. Botte, A. Scherf and M. A. Hakimi (2017). "Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites." eLife [7.7] 6. [Pubmed] [PDF]

Chen, P. B., S. Ding, G. Zanghi, V. Soulard, P. A. DiMaggio, M. J. Fuchter, S. Mecheri, D. Mazier, A. Scherf and N. A. Malmquist (2016). "Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites." Sci Rep [5.2] 6: 21802. [Pubmed] [PDF]