Alliance Française contre les Maladies Parasitaires


Sindikubwabo

Project Title : "Subversion of the host cell epigenome following infection by Toxoplasma gondii and Theileria annulata"

Project PI : Mohamed-Ali Hakimi Co-PI : Gordon Langsley

Thesis defense : october 2017

Lab : Host-pathogen interactions & Immunity to infections, IAB, Grenoble


Background :

  • Certificate, training on business companies, University Grenoble-Alpes - France (2014-2016)
  • Master's degree in Génie génétique et biochimie, University Toulouse III - France (2012-2013)
  • Master's degree in Génie biotechnologique parcours biochimie, University of La Rochelle - France (2010-2012)

Current position : Postdoctoral researcher in Raphaël Rodriguez Lab, Chemical biology of cancer, Institue Curie, Paris - France 

Publications :

Sindikubwabo, F., S. Ding, T. Hussain, P. Ortet, M. Barakat, S. Baumgarten, D. Cannella, A. Palencia, A. Bougdour, L. Belmudes, Y. Coute, I. Tardieux, C. Y. Botte, A. Scherf and M. A. Hakimi (2017). "Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites." eLife [7.7] 6. [Pubmed] [PDF]

Venugopal, K., E. Werkmeister, N. Barois, J. M. Saliou, A. Poncet, L. Huot, F. Sindikubwabo, M. A. Hakimi, G. Langsley, F. Lafont and S. Marion (2017). "Dual role of the Toxoplasma gondii clathrin adaptor AP1 in the sorting of rhoptry and microneme proteins and in parasite division." PLoS Pathog [7.0] 13(4): e1006331. [Pubmed] [PDF]

Sakura, T., F. Sindikubwabo, L. K. Oesterlin, H. Bousquet, C. Slomianny, M. A. Hakimi, G. Langsley and S. Tomavo (2016). "A Critical Role for Toxoplasma gondii Vacuolar Protein Sorting VPS9 in Secretory Organelle Biogenesis and Host Infection." Sci Rep [5.2] 6: 38842. [Pubmed] [PDF]

Sangare, L. O., T. D. Alayi, B. Westermann, A. Hovasse, F. Sindikubwabo, I. Callebaut, E. Werkmeister, F. Lafont, C. Slomianny, M. A. Hakimi, A. Van Dorsselaer, C. Schaeffer-Reiss and S. Tomavo (2016). "Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection." Nat Commun [11.3] 7: 11191. [Pubmed] [PDF]