Alliance Française contre les Maladies Parasitaires


Project Title : "Identification and characterization of new components involved in invasion of Apicomplexa parasites"

Project PI : Maryse Lebrun  Co-PI : Olivier Silvie

Thesis defense : 30/06/2017

Lab : Biogenèse membranaire et interactions avec la cellule hôte chez Plasmodium et Toxoplasma, DIMNP, Montpellier

Background :

  • Master in Microbiology and Immunology, University of Bordeaux, France (2011-2013)
  • Bachelor in Cellular Biology, University of Bordeaux, France (2008-2011)

Position after ParaFrap training : Postdoctoral researcher in Boris Striepen Lab - Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, USA 

Publications :

Berry, L., C. T. Chen, M. E. Francia, A. Guerin, A. Graindorge, J. M. Saliou, M. Grandmougin, S. Wein, C. Bechara, J. Morlon-Guyot, Y. Bordat, M. J. Gubbels, M. Lebrun, J. F. Dubremetz and W. Daher (2018). "Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny." Cell Mol Life Sci [5.8]. [Pubmed]

Thonnus, M., A. Guerin and L. Riviere (2017). "A multigene family encoding surface glycoproteins in Trypanosoma congolense." Microb Cell [no IF] 4(3): 90-97. [Pubmed]

Guerin, A., H. El Hajj, D. Penarete-Vargas, S. Besteiro and M. Lebrun (2017). "RON4L1 is a new member of the moving junction complex in Toxoplasma gondii." Sci Rep [4.3] 7(1): 17907. [Pubmed]

Guerin, A., R. M. Corrales, M. L. Parker, M. H. Lamarque, D. Jacot, H. El Hajj, D. Soldati-Favre, M. J. Boulanger and M. Lebrun (2017). "Efficient invasion by Toxoplasma depends on the subversion of host protein networks." Nat Microbiol [no IF] 2(10): 1358-1366. [Pubmed]

Parker, M. L., D. M. Penarete-Vargas, P. T. Hamilton, A. Guerin, J. P. Dubey, S. J. Perlman, F. Spano, M. Lebrun and M. J. Boulanger (2016). "Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair." Proc Natl Acad Sci U S A [9.4] 113(2): 398-403. [Pubmed]

Rugarabamu, G., J. B. Marq, A. Guerin, M. Lebrun and D. Soldati-Favre (2015). "Distinct contribution of Toxoplasma gondii rhomboid proteases 4 and 5 to micronemal protein protease 1 activity during invasion." Mol Microbiol [4.4] 97(2): 244-262. [Pubmed]