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ABOUT
- Who are we
- Objectives of the LabEx
- Laboratories and teams
- Directory Board
- Industrial collaborators
- Institutional and Financial Supports
- GOVERNANCE
- Organigram
- Steering committee
- Executive Committee
- External Scientific Advisory Board
- Institutional Board
- TRAINING
- CONFERENCES
- PROJECTS
- Post genomic data exploration
- Mechanisms of pathogenesis
- Parasite molecular and cellular biology
- Towards new intervention strategies against parasitic pathogens
- Plateforms
- VALORIZATION
-
ABOUT
- Who are we
- Objectives of the LabEx
- Laboratories and teams
- Directory Board
- Industrial collaborators
- Institutional and Financial Supports
- GOVERNANCE
Project Title : "Identification of new compounds with activity against Toxoplasma gondii and Plasmodium. Applications to develop new anti-parasitic agents directed to novel targets"
Project PI : Mohamed-Ali Hakimi Co-PI : Cyrille Botté
BACKGROUND
- Post-doc in EMBL-Grenoble Outstation, Grenoble, France (2015-2016)
- PhD student in Unit of Virus Host Cell Interactions (UVHCI UMR3265) Grenoble, France (2012-2015)
POSITION AFTER PARAFRAP TRAINING
Postdoctoral researcher at CNRS, IAB, Grenoble, France
PUBLICATIONS
Dard, C., Swale, C., Brenier-Pinchart, M.-P., Farhat, D.C., Bellini, V., Robert, M.G., Cannella, D., Pelloux, H., Tardieux, I., Hakimi, M.-A., (2021). A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection. BMC Biology [6.8] 19, 25. doi: 10.1186/s12915-021-00959-9
Farhat, D.C., Bowler, M.W., Communie, G., Pontier, D., Belmudes, L., Mas, C., Corrao, C., Coute, Y., Bougdour, A., Lagrange, T., Hakimi, M., Swale, C. (2021). A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental genes partitioning in Toxoplasma. bioRxiv [preprint] 2021.02.23.432502. doi: 10.1101/2021.02.23.432502
Bellini, V., Swale, C., Brenier-Pinchart, M.-P., Pezier, T., Georgeault, S., Laurent, F., Hakimi, M.-A., Bougdour, A., (2020). Target identification of an antimalarial oxaborole identifies AN13762 as an alternative chemotype for targeting CPSF3 in apicomplexan parasites. iScience [4.4] doi: 10.1016/j.isci.2020.101871
Farhat, D.C., Swale, C., Dard, C., Cannella, D., Ortet, P., Barakat, M., Sindikubwabo, F., Belmudes, L., De Bock, P.-J., Couté, Y., Bougdour, A., Hakimi, M.-A., (2020). A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment. Nat Microbiol [14.6] 1–14. doi: 10.1038/s41564-020-0674-4
Swale, C., A. Bougdour, A. Gnahoui-David, J. Tottey, S. Georgeault, F. Laurent, A. Palencia and M.-A. Hakimi (2019). "Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection." Sci Transl Med [17.2] 11(517): eaax7161. [PDF]
Friday, 06 October 2023Success for ParaFrap at MPM2023
Success for ParaFrap students at MPM2023 Parafrap students won numerous awards at the MPM 2023, Woods Hole USA, 17-21 September 2023. A warm congratulations to all ! Parul Sharma (2nd year PhD under the...
Thursday, 14 September 2023Predoc & Posdoc Offers l Plasmodium l Barcelona
Predoctoral and Postdoctoral positions - Barcelona, Spain Project Leader: Alfred Cortés, PhD - Barcelona Institute for Global Health Hospital Clínic - Universitat de Barcelona Positions: A predoctoral and two...
Thursday, 07 September 2023PhD Offer l Plasmodium/Schistosoma l Perpignan
PhD Position Perpignan, France Project Leader Ronaldo DE CARVALHO AUGUSTO (CPJ, UPVD), principal supervisor (50%) Jérôme BOISSIER (PU, UPVD), PI (50%) Project: Unveiling the Dark Secrets of Roommate Parasites: A Study...
Thursday, 07 September 2023PostDoc l Toxoplasma l California, USA
PostDoc position : Saeij Lab, Davis, California, USA The Saeij lab (https://saeijlab.faculty.ucdavis.edu/) at the University of California, Davis, is currently looking for several postdoctoral scholars to work on...
Wednesday, 06 September 2023PostDoc l Cryptosporidium l Tours, France
PostDoc position : Identify new repository molecules against Cryptosporidium, Tours, France The lab seeks to hire a highly motivated candidate to work on the identification of new repository molecules against...
Monday, 15 May 2023Emerging Leader Research Fellow - UK
Emerging Leader Research Fellow, Oxford Brookes University, UK The Oxford Brookes University offers an opportunity to develop an independent research group in molecular parasitology/protistology through a...
Wednesday, 05 April 2023PostDoc l P. falciparum l Montpellier
PostDoc position : Gene regulation/ DNA low complexity regions-DNA binding proteins, Montpellier, France The post-doc project aims to investigate the role of Low Complexity Regions in regulation of gene expression in P....
Monday, 03 April 2023Short Term Scientific Mission Grants
Short-Term Scientific Missions (STSMs) within the OneHealthdrugs (CA21111) network 1st CALL for applications 2023 The 1st STSM Call of the Action CA2111 OneHealthdrugs is launched. Short Term Scientific Mission...
Tuesday, 28 March 2023PostDoc l Immunity T. gondii l Lille
PostDoc position : Cross-talk between stress response and infection in dendritic cells at Institut Pasteur Lille, France We seek to hire a highly motivated candidate to work on the role of the Unfolded Protein...
Friday, 27 January 2023Nouvelles données sur l'invasion de Toxoplasma gondii
[Publication] Les derniers travaux de Rania Najm, Hiba El Hajj, Maryse Lebrun & leurs collègues sont publiés dans PNAS. Les auteurs apportent des connaissances importantes sur les acteurs moléculaires de l'invasion des bradyzoïtes et...
TRAINING PROGRAM
International PhD ProgramPostdoctoral ProgramNEWS
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