

Research in parasitology is multidisciplinary. In addition to molecular biology, cellular biology and biochemistry, it includes, at least in the major human diseases, a strong component of immunology in addition to field epidemiology, clinical research and human and vector genetics. New scientific opportunities are provided by the recently available genome information for most major parasites and their hosts. Combining the state-of-the-art of fundamental research and translational applications, we expect to defeat major parasitic diseases such as malaria, toxoplasmosis, leishmaniasis, African trypanosomiasis, amoebiasis and theileriosis. Although many of the listed diseases occur in the developing world, there are new emergences of these parasitic infections world wide.
The major focus of ParaFrap is the collaboration and further integration of laboratories from disease endemic countries (Africa, India and Latin America) to the consortium. Collaborations with research groups from endemic countries underline the opportunity to validate ‘bench’ work in the field using clinical isolates and perform integrated studies on the disease in its natural environment. On the other hand, particular virulence factors observed in patients or animals infected with field isolates have been explored at the molecular level in high tech laboratories in France. Collaborations with laboratories located in disease endemic countries will be further strengthened by ParaFrap. For example, students from these countries are invited to apply to the PhD program, post doc positions and workshops. The planned biennial meeting will be publicized widely in these countries. Emphasis on the already existing interactions with developing countries, in particular Africa, India, Latin America and China will be one of our major goals. At present, the key strength of the French Parasitology research relies on parasitic diseases caused by protozoan pathogens. For this reason, ParaFrap initially will focus on malaria and toxoplasmosis and other neglected diseases of increasing public health concern including trypanosomiosis, leishmaniasis, bovine tropical theileriosis and amoebiasis. ParaFrap will be open to integrate excellent laboratories working on other parasitic pathogens in the future.
Another goal of ParaFrap is to bring together leading French researchers and establish stable inter-institutional and structural scientific links via a joint scientific and training programs and shared infrastructures. The integration of expertise from academic, industry and laboratories in disease endemic countries should enhance existing studies in basic parasitology research and accelerate translational aspects (diagnosis and intervention strategies) for many major parasitic pathogens.
Taken together, ParaFrap aims to strengthen significantly France’s position as an international leader in this domain. In order to keep ParaFrap open to the French Parasitology community, collaborative research projects and PhD student sandwich fellowships can integrate participants outside the initial core group of the consortium. This will keep the network open and will allow the continual integration of excellent and complementary groups. Another integrating activity is going to be the biennial meeting that will be open to the entire French Parasitology community. This meeting will allow students and post doc to present their data as talks/posters in the presence of PIs and the external Scientific Advisory Board.
[Publication] Les derniers travaux de Rania Najm, Hiba El Hajj, Maryse Lebrun & leurs collègues sont publiés dans PNAS. Les auteurs apportent des connaissances importantes sur les acteurs moléculaires de l'invasion des bradyzoïtes et...
LabEx ParaFrap wishes you happiness, health, science and success for 2023. First news from the network this year: the ParaFrap webinars will be back in 2023, as in previous years, every second Thursday of the month at 3pm. If you are not yet on the...
PostDoc position in Biological Sciences / Biochemistry: Mode of action of antimalarial benzylmenadiones at IBMC, Strasbourg, France A renewable 1-year postdoctoral position is open at IBMC (Inserm/CNRS/University...
[Communiqué] Gerald Spaeth, head of the "Molecular Parasitology and Signalling" unit at the Institut Pasteur Paris, has been awarded a Synergy grant from the European Research Council (ERC) for the project "DECOLeishRN - Decoding...
PostDoc position studying host-pathogen interactions at Institut Pasteur, Paris, France A postdoc position is available at the Institut Pasteur in the signalling and host-parasite interactions group, headed by Najma Rachidi, to investigate the...
[Communiqué] The team of Dr Chetan Chitnis from the Institut Pasteur, a partner in LabEx ParaFrap, has studied the blood stage of the Plasmodium falciparum parasite, which causes the most severe and deadly form of malaria, and discovered a...
PhD Position in Single Particle Imaging of P. falciparum Knobs Project Leader Prof. Dr. Michael Lanzer (Heidelberg University Hospital, Centre for Infectious Diseases, Parasitology Unit, INF 324, 69120 Heidelberg, Germany)...
PostDoc position in Biological Chemistry/Biochemistry/Proteomics at University of Strasbourg, France A renewable 6 month post-doctoral position is open at the ECPM (University of Strasbourg) to use activity-based protein...
Dear colleagues,The EMBO Workshop "New frontiers in host-parasite interactions, from cell to organism", supported by...
Position: External Recruitment Competition (permanent position) - Assistant Engineer in biology, life and earth sciences Details:Study of the cytoskeleton in Trypanosoma brucei and Toxoplasma gondii...
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