mRNA-based malaria vaccines, Paris, France 

The Malaria Parasite Biology and Vaccines Unit at Institut Pasteur (Prof. Chetan Chitnis), Paris announces a position for a post-doctoral fellow on a project to develop mRNA-based malaria vaccines that is available immediately.

Additional job details : 

Postdoc_Aug2024_Chitnis.pdf

Computational postdoctoral researcher in malaria and erythropoiesis, Montpellier, France 

The MIVEGEC Lab is seeking a highly motivated and talented postdoctoral researcher to join our team investigating the effects of malaria parasites on erythropoiesis with a focus on single-cell transcriptomics data. This project aims to uncover the complex interactions between malaria parasites and red blood cell production, providing insights that could lead to new therapeutic strategies.

Key Responsibilities under the supervision of Arthur Talman:

• Lead the data analysis of human and parasite single-cell transcriptomics data from in vitro and in vivo samples.
• Develop and implement computational pipelines for the analysis and interpretation of high-throughput sequencing data.
• Collaborate with a multidisciplinary team of researchers, including biologists, bioinformaticians, and clinicians.
• Contribute to the preparation of manuscripts, grant proposals, and presentations.
• Mentor graduate students as needed..

Your future team

• Stimulating and collaborative team with several ambitious projects running in the lab.
• Opportunity to lead innovative research in a supportive and inclusive environment.
• Access to state-of-the-art facilities and resources.
• Collaborative project with Institute Cochin (Teams of Frédérique Verdier and Catherine Lavazec).
• Numerous professional training and development opportunities, including mentorship and training.
• Collaborative and multidisciplinary research community developmental biology and parasitology communities in Montpellier.
• Salary adjusted to experience.

You

Qualifications:

• Ph.D. in bioinformatics, computational biology, genomics, or a related field.
• Strong background in single-cell transcriptomics and experience with data analysis tools.
• Proficiency in programming languages such as R or Python.
• Experience with high-performance computing environments.
• Excellent problem-solving skills and the ability to work independently and as part of a team.
• Strong written and verbal communication skills in english.
• Commitment to diversity, equity, and inclusion in the research environment.

Preferred Qualifications:

• Experience in erythropoiesis or malaria.
• Familiarity with statistical methods for genomics data analysis.
• Demonstrated track record of peer-reviewed publications.

Application

Additional job details : https://euraxess.ec.europa.eu/jobs/244920

Deadline to apply : 15/08/2024

Start date : 01/10/2024

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PhD Opportunity, Tours, France

Supervision

Thesis Supervisor: Sonia LAMANDE; Co-Supervisor: Julie TOTTEY

Project:

FUNTIONAL CHARACTERISATION OF CYSTEINE CATHEPSINS IN THE APICOMPLEXAN PARASITE CRYPTOSPORIDIUM PARVUM

Skills and Experience:

• In the final year of Master's (or equivalent) or already holding a Master's degree (or equivalent), preferably in biology or microbiology.
• Curious, motivated student who enjoys teamwork but also demonstrates autonomy and critical thinking.
• Previous laboratory research internship experience in the field of infectious diseases or parasitology is appreciated.
• Technical skills in cell culture in a level 2 confined laboratory, molecular biology (qRT-PCR, cloning, transfection), and/or biochemistry (enzyme activity) would be advantageous.
• The thesis project involves animal experiments.
• Proficiency in French and English and ability to communicate fluently (written and oral) in both languages.

Application:

Contact Sonia LAMANDE and Julie TOTTEY (see attached file).

Start: October 1, 2024

Application Deadline: April 17, 2024

Offre_de_thèse_TOTTEY_LAMANDE.pdf

Senior PostDoc position : computational biologist, Paris, France 

The ParSig team (https://research.pasteur.fr/en/team/molecular-parasitology-and-signaling) at the Institut Pasteur in Paris seeks for a highly qualified computational biologist at the senior postdoc/research assistant level to join the ERC Synergy project DecoLeishRN (https://cordis.europa.eu/project/id/101071613). The successful candidate should have at least 3 years of postdoc experience in the fields of bioinformatics and population genetics and should be motivated to establish a cutting-edge project that will serve as a springboard to independence.

The selected candidate will join and collaborate with a vibrant, international team that applies experimental evolution to study mechanisms of fitness gain in the eukaryotic pathogen Leishmania. In particular, the candidate will (i) apply and further develop our previously established bioinformatics pipeline (GIP, Bussotti et al., NAR 2022, http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8989552/ [ncbi.nlm.nih.gov]), (ii) integrate various large data sets generated by short-read, long-read and single cell DNAseq and RNAseq analyses during parasite evolution in vitro and in vivo, and (iii) establish new computational tools in collaboration with local resources and with our partner at the Weizmann Institute of Sciences to study the evolution of regulatory networks underlying Leishmania fitness gain. Wet lab experience is not required, but a solid background in biology will be of advantage.

Application

Interested candidates should send a motivation letter, CV (including 3 names for references) and list of publications to This email address is being protected from spambots. You need JavaScript enabled to view it.. This call will be open until a suitable candidate has been recruited.