

Parasitic infections remain a major cause of morbidity and mortality worldwide. The vast majority of infections in humans and domestic animals can be attributed to protozoan pathogens responsible for malaria, African trypanosomiasis (sleeping sickness, nagana, etc), leishmaniasis and toxoplasmosis. In addition, parasitic infections kill millions of livestock, which strongly affect rural development and poverty alleviation in developing countries (as an example, estimation of economic losses caused by African trypanosomoses is US$ 4.75 billion per year). ParaFrap in a joint effort with industrial partners aims to improve the health situation disease endemic countries.
To favor the transfer to the economic world, ParaFrap will reinforce its ongoing connections with industrial partners, including Sanofi-Aventis, Novartis, Virbac, CEVA Santé Animale, and a number of Small & Medium Enterprise. A number of projects are already supported by patents and we anticipate that most of the new collaborative projects stimulated by ParaFrap will generate innovation and numerous new patents that will be developed in close collaboration with industrial partners linked to ParaFrap for commercial exploitation. An industry representative will be involved in the governance (Executive Committee) to facilitate and stimulate collaborative research between industrial and academic partners.
The ParaFrap website is created with a public section to create awareness for the consortium activities including updates and announcements of major break through results of the consortium in basic research and new intervention strategies. In addition, an informative section will be created with facts about major parasitic diseases and their treatment. This will include the creation of a database of experts in parasitology (including contact address). The web site also will be an excellent communication tool between consortium members (announcement of workshops, PhD program etc.). A major impact on the creation of new jobs will be an important secondary effect of this LabEx. ParaFrap will create highly competitive PhD program with 20 well-trained students and 20 post docs. At the end of their training, we will promote their integration in industry research programs (through existing partnership with private company or through the Sup’Biotech Engineer School connections) or alternatively assist them in finding excellent postdoc positions in leading international institutions. ParaFrap participants have excellent international connections through the organization of international conferences and workshops. We will help excellent post docs and young group leaders to integrate into one of the French Institutions (staff position). Taken together, ParaFrap will promote a highly competitive industry research on parasitology that should feed back on creating a number of new jobs. This environment will be very favorable for innovative research and the creation of new start up companies. A good example is Man Ros Therapeutics that has been recently created by a CNRS scientist.
Emerging Leader Research Fellow, Oxford Brookes University, UK The Oxford Brookes University offers an opportunity to develop an independent research group in molecular parasitology/protistology through a...
PostDoc position : Gene regulation/ DNA low complexity regions-DNA binding proteins, Montpellier, France The post-doc project aims to investigate the role of Low Complexity Regions in regulation of gene expression in P....
Short-Term Scientific Missions (STSMs) within the OneHealthdrugs (CA21111) network 1st CALL for applications 2023 The 1st STSM Call of the Action CA2111 OneHealthdrugs is launched. Short Term Scientific Mission...
PostDoc position : Cross-talk between stress response and infection in dendritic cells at Institut Pasteur Lille, France We seek to hire a highly motivated candidate to work on the role of the Unfolded Protein...
[Publication] Les derniers travaux de Rania Najm, Hiba El Hajj, Maryse Lebrun & leurs collègues sont publiés dans PNAS. Les auteurs apportent des connaissances importantes sur les acteurs moléculaires de l'invasion des bradyzoïtes et...
LabEx ParaFrap wishes you happiness, health, science and success for 2023. First news from the network this year: the ParaFrap webinars will be back in 2023, as in previous years, every second Thursday of the month at 3pm. If you are not yet on the...
PostDoc position in Biological Sciences / Biochemistry: Mode of action of antimalarial benzylmenadiones at IBMC, Strasbourg, France A renewable 1-year postdoctoral position is open at IBMC (Inserm/CNRS/University...
[Communiqué] Gerald Spaeth, head of the "Molecular Parasitology and Signalling" unit at the Institut Pasteur Paris, has been awarded a Synergy grant from the European Research Council (ERC) for the project "DECOLeishRN - Decoding...
PostDoc position studying host-pathogen interactions at Institut Pasteur, Paris, France A postdoc position is available at the Institut Pasteur in the signalling and host-parasite interactions group, headed by Najma Rachidi, to investigate the...
[Communiqué] The team of Dr Chetan Chitnis from the Institut Pasteur, a partner in LabEx ParaFrap, has studied the blood stage of the Plasmodium falciparum parasite, which causes the most severe and deadly form of malaria, and discovered a...
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