Project Title : "Role of the unusual peroxisomal/glycosomal sequestration of cytosolic metabolic pathways in trypanosomes" Project PI : Frédéric Bringaud Co-PI : Cyrille Botté Lab : Intermediate and energy metabolism of trypanosomes, UMR5234 CNRS, Bordeaux University |
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BACKGROUND
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POSITION AFTER PARAFRAP TRAINING Postdoctoral researcher at IRCM (Institut de Recherche en Cancérologie de Montpellier), France - Since March 2021 |
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PUBLICATIONS Villafraz, O., Biran, M., Pineda, E., Plazolles, N., Cahoreau, E., Souza, R.O.O., Thonnus, M., Allmann, S., Tetaud, E., Rivière, L., Silber, A.M., Barrett, M.P., Zíková, A., Boshart, M., Portais, J.-C., Bringaud, F., (2021b). Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline. PLoS Pathog [6.2] 17, e1009204. doi: 10.1371/journal.ppat.1009204 Villafraz, O., Baudouin, H., Mazet, M., Kulyk, H., Dupuy, J.-W., Pineda, E., Botté, C., Inaoka, D., Portais, J.-C., Bringaud, F., (2021a). The trypanosome UDP-glucose pyrophosphorylase is imported by piggybacking into glycosomes where unconventional sugar nucleotide synthesis takes place. bioRxiv [preprint] 2021.02.17.431754. doi: 10.1101/2021.02.17.431754 Michels, P.A.M., Villafraz, O., Pineda, E., Alencar, M.B., Cáceres, A.J., Silber, A.M., Bringaud, F., (2021). Carbohydrate metabolism in trypanosomatids: new insights revealing novel complexity, diversity and species-unique features. Exp Parasitol [1.7] 108102. doi: 10.1016/j.exppara.2021.108102 Wargnies, M., Plazolles, N., Schenk, R., Villafraz, O., Dupuy, J.-W., Biran, M., Bachmaier, S., Baudouin, H., Clayton, C., Boshart, M., Bringaud, F., (2021). Metabolic selection of a homologous recombination mediated gene loss protects Trypanosoma brucei from ROS production by glycosomal fumarate reductase *. J Biol Chem [4.2] 0, 100548. doi: 10.1016/j.jbc.2021.100548 Allmann, S., Wargnies, M., Cahoreau, E., Biran, M., Plazolles, N., Morand, P., Pineda, E., Kulyk, H., Asencio, C., Villafraz, O., Rivière, L., Tétaud, E., Rotureau, B., Mourier, A., Portais, J.-C., Bringaud, F., (2019). “Metabolic contest”, a new way to control carbon source preference. bioRxiv [preprint] 800839. doi: 10.1101/800839 Wargnies, M., E. Bertiaux, E. Cahoreau, N. Ziebart, A. Crouzols, P. Morand, M. Biran, S. Allmann, J. Hubert, O. Villafraz, Y. Millerioux, N. Plazolles, C. Asencio, L. Rivière, B. Rotureau, M. Boshart, J.-C. Portais and F. Bringaud (2018). "Gluconeogenesis is essential for trypanosome development in the tsetse fly vector." PLoS Pathog [6.6] 14(12): e1007502. doi: 10.1371/journal.ppat.1007502 |
Ana Rita Gomes, a CNRS Research Associate at the Laboratory of Pathogens and Host Immunity in Montpellier, and former Postdoctoral fellow of the LabEx ParaFrap, has been awarded the prestigious CNRS Bronze Medal in 2023. This...
. PhD Opportunity, Tours, France Supervision Thesis Supervisor: Sonia LAMANDE; Co-Supervisor: Julie TOTTEY Project: FUNTIONAL CHARACTERISATION OF CYSTEINE CATHEPSINS IN THE APICOMPLEXAN PARASITE CRYPTOSPORIDIUM...
Senior PostDoc position : computational biologist, Paris, France The ParSig team (https://research.pasteur.fr/en/team/molecular-parasitology-and-signaling) at the Institut Pasteur in Paris seeks for a highly...
Researcher in Livestock Immunology for the Study of Animal Trypanosomoses Through a One Health approach, the Intertryp Joint Research Unit (Cirad-IRD) is developing research on interactions between hosts,...
Happy New Year 2024! To kick off this new scientific year, here is the ParaFrap webinar schedule. Since January 2021, ParaFrap has been organizing a series of webinars. This monthly event, held every 2nd Thursday of the month, aims to strengthen...
PostDoc position : functional analysis of P. falciparum early gametocyte proteins, Allschwil, Switzerland The Malaria Gene Regulation Lab of Till Voss is looking for a highly motivated and talented postdoc to...
The team of Dr. Mohamed-Ali Hakimi, in collaboration with Isabelle Coppens (Johns Hopkins University Bloomberg School of Public Health and Malaria Research Institute, Baltimore, MD, USA), has developed a new (epi)genetic method to produce in vitro...
Success for ParaFrap students at MPM2023 Parafrap students won numerous awards at the MPM 2023, Woods Hole USA, 17-21 September 2023. A warm congratulations to all ! Parul Sharma (2nd year PhD under the...
Predoctoral and Postdoctoral positions - Barcelona, Spain Project Leader: Alfred Cortés, PhD - Barcelona Institute for Global Health Hospital Clínic - Universitat de Barcelona Positions: A predoctoral and two...
PhD Position Perpignan, France Project Leader Ronaldo DE CARVALHO AUGUSTO (CPJ, UPVD), principal supervisor (50%) Jérôme BOISSIER (PU, UPVD), PI (50%) Project: Unveiling the Dark Secrets of Roommate Parasites: A Study...
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