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Project : "Identification of malaria parasite virulence factors that counteract mosquito natural resistance" Project PI : Stéphanie Blandin Co-PI : Olivier Silvie Lab : Responses in the Anopheles gambiae Malaria Vector, IBMC, University of Strasbourg, France |
BACKGROUND
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POSITION AFTER PARAFRAP TRAINING
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PUBLICATIONS Feng, L., D. A. Lanfranchi, L. Cotos, E. Cesar-Rodo, K. Ehrhardt, A.-A. Goetz, H. Zimmermann, F. Fenaille, S. A. Blandin and E. Davioud-Charvet (2018). "Synthesis of plasmodione metabolites and 13C-enriched plasmodione as chemical tools for drug metabolism investigation." Org Biomol Chem [3.6] 16(15): 2647-2665. [Link] Urgin, K., M. Jida, K. Ehrhardt, T. Muller, M. Lanzer, L. Maes, M. Elhabiri and E. Davioud-Charvet (2017). "Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties." Molecules [2.5] 22(1). [Link] Jida, M., C. P. Sanchez, K. Urgin, K. Ehrhardt, S. Mounien, A. Geyer, M. Elhabiri, M. Lanzer and E. Davioud-Charvet (2017). "A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs." ACS Infect Dis [no IF] 3(2): 119-131. [Link] Rodo, E. C., L. Feng, M. Jida, K. Ehrhardt, M. Bielitza, J. Boilevin, M. Lanzer, D. L. Williams, D. A. Lanfranchi and E. Davioud-Charvet (2016). "A Platform of Regioselective Methodologies to Access Polysubstituted 2-Methyl-1,4-naphthoquinone Derivatives: Scope and Limitations." European Journal of Organic Chemistry [3.1] 2016(11): 1982-1993. [Link] Ehrhardt, K., C. Deregnaucourt, A. A. Goetz, T. Tzanova, V. Gallo, P. Arese, B. Pradines, S. H. Adjalley, D. Bagrel, S. Blandin, M. Lanzer and E. Davioud-Charvet (2016). "The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites." Antimicrob Agents Chemother [4.5] 60(9): 5146-5158. [Link] Bielitza, M., D. Belorgey, K. Ehrhardt, L. Johann, D. A. Lanfranchi, V. Gallo, E. Schwarzer, F. Mohring, E. Jortzik, D. L. Williams, K. Becker, P. Arese, M. Elhabiri and E. Davioud-Charvet (2015). "Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats." Antioxid Redox Signal [7.7] 22(15): 1337-1351. [Link] Ehrhardt, K., E. Davioud-Charvet, H. Ke, A. B. Vaidya, M. Lanzer and M. Deponte (2013). "The antimalarial activities of methylene blue and the 1,4-naphthoquinone 3-[4-(trifluoromethyl)benzyl]-menadione are not due to inhibition of the mitochondrial electron transport chain." Antimicrob Agents Chemother [4.5] 57(5): 2114-2120. [Link] |
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LabEx ParaFrap wishes you happiness, health, science and success for 2023. First news from the network this year: the ParaFrap webinars will be back in 2023, as in previous years, every second Thursday of the month at 3pm. If you are not yet on the...
PostDoc position in Biological Sciences / Biochemistry: Mode of action of antimalarial benzylmenadiones at IBMC, Strasbourg, France A renewable 1-year postdoctoral position is open at IBMC (Inserm/CNRS/University...
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[Communiqué] The team of Dr Chetan Chitnis from the Institut Pasteur, a partner in LabEx ParaFrap, has studied the blood stage of the Plasmodium falciparum parasite, which causes the most severe and deadly form of malaria, and discovered a...
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