The Apicolipid team, ParaFrap member (Institute for Advanced Biosciences, CNRS/Inserm/ Université Grenoble Alpes), with researchers from the University of Melbourne, has just published two studies in Cell Microbiology and PLOS Pathogens. These studies show that to survive, the parasites responsible for malaria and toxoplasmosis depend on mechanisms inherited from the plant world. This discovery is a major advance for the development of new therapeutic targets for these parasites, which have such substantial public health consequences.
Find the press releases HERE.
Bibliography :
Characterization of the Plasmodium falciparum and P. berghei glycerol 3-phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast, Shears MJ, MacRae JI, Mollard V, Goodman CD, Sturm A, Orchard LM, Llinás M, McConville MJ, Botté CY*, McFadden GI*. Cell Microbiology, 20 juin 2016. Link
Apicoplast-localized lysophosphatidic acid precursor assembly is required for bulk phospholipid synthesis in Toxoplasma gondii and relies on an algal/plant-like glycerol 3-phosphate acyltransferase, Amiar S, MacRae JI, Callahan DL, van Dooren GG, Shears MJ, Dubois D, Cesbron-Delauw MF, Maréchal E, McConville MJ, McFadden GI, Yamaryo-Botté Y*, Botté CY*. PLOS Pathogens, 4 août 2016. Link
Postdoctoral position, Institut Pasteur, Paris, France A postdoc position is available at the Institut Pasteur Paris, in the signalling and host-parasite interactions research group, headed by Dr Najma Rachidi...
Postdoctoral Research Associate, York, UK Applications are invited for a postdoctoral researcher for 36 months to characterise the signalling pathways that regulate autophagy, lysosome exocytosis and biomolecular...
mRNA-based malaria vaccines, Paris, France The Malaria Parasite Biology and Vaccines Unit at Institut Pasteur (Prof. Chetan Chitnis), Paris announces a position for a post-doctoral fellow on a project to develop...
ABOUT SPEAKERS PROGRAMME REGISTRATION CONTACT LOCATION About the workshop ParaFrap is organizing the ParaFrap Next Generation in Parasitology...
Computational postdoctoral researcher in malaria and erythropoiesis, Montpellier, France The MIVEGEC Lab is seeking a highly motivated and talented postdoctoral researcher to join our team investigating the...
[Communiqué] As part of the actions of the Health Innovation Plan 2030, the health component of the France 2030 plan, Mohamed-Ali Hakimi is one of the 22 laureates of an Excellence Chair in Biology/Health, supported to conduct high-level research...
The York Biomedical Research Institute (YBRI) are hosting an online live seminar on Friday 24th May 1-2pm BST as part of their biomedical science seminar series. You are all welcome to attend - registration is required via the...
[Communiqué] Congratulations to Arthur Talman, IRD Research Leader in the MIVEGEC laboratory (Montpellier), who has been awarded an Advanced Grant from the European Research Council (ERC) for the project "TROJAN - Molecular mimicry and immune...
Ana Rita Gomes, a CNRS Research Associate at the Laboratory of Pathogens and Host Immunity in Montpellier, and former Postdoctoral fellow of the LabEx ParaFrap, has been awarded the prestigious CNRS Bronze Medal in 2023. This...
. PhD Opportunity, Tours, France Supervision Thesis Supervisor: Sonia LAMANDE; Co-Supervisor: Julie TOTTEY Project: FUNTIONAL CHARACTERISATION OF CYSTEINE CATHEPSINS IN THE APICOMPLEXAN PARASITE CRYPTOSPORIDIUM...
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