Two PostDoc positions on Trypanosoma brucei and its interactions with blood vessels, Lisbon, Portugal 

A collaborative project in the Lisbon area, Portugal, to explore groundbreaking interactions between Trypanosoma brucei and blood vessels. This parasite, notorious for causing devastating diseases in Africa, crosses blood vessels to invade critical organs like adipose tissue and the brain, complicating treatment and exacerbating disease outcomes. Our project, a collaborative endeavor between the Luisa Figueiredo Lab (Gulbenkian Institute for Molecular Medicine - GIMM, Lisbon) and the Claudio Franco Lab (Catolica Biomedical Research - CBR, Oeiras), seeks to unravel the molecular and cellular interactions between T. brucei and endothelial cells during parasite crossing. Insights from this research could pave the way for novel treatment strategies not only for trypanosomiasis but also for related inflammatory and oncological conditions.

Projects

Position 1 – L. FIGUEIREDO Lab (GIMM, Lisbon) Focus: Characterizing parasite features essential for the crossing of blood vessels. Techniques: The successful candidate will employ a suite of cutting-edge tools, including parasite genetics, in vitro crossing assays, genomic analysis, bioinformatics, cell sorting, advanced microscopy, and mouse infection models.

Position 2 – C. FRANCO Lab (CBR, Oeiras) Focus: Investigating endothelial cell phenotypes during parasite crossing at the single-cell level. Techniques: This role will utilize single-cell RNAseq, super-resolution and live imaging microscopy, mouse genetic manipulation, and in vitro assays to provide insights into vascular dynamics during infection.

Prerequisites

Two independent yet collaborative thinkers with a passion for solving complex biological puzzles. Candidates should possess a doctoral degree in life sciences and have a strong background in molecular biology, cell culture, bioinformatics, or imaging techniques.

Application

Submit a CV, a statement of research interests, and two reference contacts to positions@gimm.pt, indicating the reference CrossTryp. Applications will be reviewed on a rolling basis until positions are filled.

CrossTryp-2_positions.pdf

Postdoctoral position, Institut Pasteur, Paris, France 

A 24-month post-doctoral position starting on March 1st 2025 and funded by the French National Research Agency (ANR) is available in the Trypanosome Cell Biology Unit at Institut Pasteur in Paris (Trypanosome Transmission Group: https://research.pasteur.fr/en/team/group-brice-rotureau/).

Application

Applicants should send a CV, a bibliography, a motivation letter and the names of three references in a single pdf file to Dr. Brice Rotureau (rotureau@pasteur.fr) before November 30th 2024.

Post-doc_call_2024_final.pdf

Postdoctoral positions, LPHI Lab, Montpellier, France 

Two ERC-funded (JANUS 2024-2029) postdoc positions are open in the lab to study cell cycle regulation in malaria parasites https://lphi.umontpellier.fr/research-teams/molecular-approaches-to-new-antimalarial-strategies/gomes/. The successful candidates will lead an exciting ERC-funded project investigating the cell cycle of malaria parasites using cutting-edge genetics and omics techniques.

Application

Application Deadline: 01.11.2024 - Position Start Date: January 2025 (flexible) - Details in the attached documents

ERCpostdocs_pb.pdf

ERCpostdocs_pf.pdf

Postdoctoral position, Institut Pasteur, Paris, France 

A postdoc position is available at the Institut Pasteur Paris, in the signalling and host-parasite interactions research group, headed by Dr Najma Rachidi and the Antibody engineering platform, headed by Dr Pierre Lafaye to generate nanobodies against Leishmania CK1.2 and to assess their neutralizing properties. (https://research.pasteur.fr/en/team/signalling-and-host-parasite-interactions/; https://research.pasteur.fr/fr/team/antibody-engineering/).

The contract is for two years and will start no later than the 2nd of January 2025, before would be better.

Application

Applications should be sent before the 22nd of November 2024. Additional job details can be found in the following file:

postdoc_project_DARRI.pdf