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Alliance Française contre les Maladies Parasitaires


 university of cambridge

Projet: 
Little is known about how eukaryotic pathogens move about in a vertebrate host. We have developed an experimental model based on trypanosome infection of transparent zebrafish larvae that enables the behaviour of trypanosomes and the response of the host to be investigated at single cell resolution in a live vertebrate host. A post-doctoral research assistant position is available to improve the experimental system by developing transgenic trypanosomes expressing sufficient fluorescent protein to allow time lapse imaging of trypanosome movement between tissues and identify any preferred locations for proliferation. Combining these trypanosomes with transgenic zebrafish lines with various immune cell lineages marked with a different fluorescent protein will enable us to characterise the cellular immune response to infection.

Encadrement:
Mark Carrington (Molecular Cell Biology of Trypanosomes, Department of Biochemistry, Cambridge University, UK) & Maria Forlenza (Comparative Immunology Unit, Department of Animal Sciences, Wageningen, The Netherlands)

Qualifications et expériences:

1. Cell biology, preferably with protozoa.
2. Microscopy, preferably live cell imaging.
3. A good background in basic Molecular Biology and/or zebrafish handling is desirable but not required.

The successful applicant will be expected to work both in Cambridge (UK) and in Wageningen (The Netherlands), probably spending at least 12 months in each location.

Questions ?

Informal enquiries can be sent to Mark Carrington Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser. and Maria Forlenza Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser.

Date limite de candidature:

30 April 2021

Plus d'informations et candidature: 

https://www.jobs.cam.ac.uk/job/29148/

pdfResearchAssociate-PH26088.pdf

 SwissTPH

Titre du projet: 
Postdoctoral Fellow in Basic Malaria Research

Encadrement:
Prof. Nicolas Brancucci (Malaria Host Interactions Unit at Swiss TPH, Basel, Suisse)

Début du contrat:
01/07/2021

Qualifications et expériences:

  • Cell culture (mammalian and ideally P. falciparum or other protozoan parasites)
  • Molecular cloning and transfection
  • Transcriptomics and (phospho-) proteomics techniques, incl. analysis
  • Excellent command (speaking and writing) of English
  • Enthusiasm for studying malaria parasite biology

Questions ?

For more information about this position, please contact:
Prof. Nicolas Brancucci, Head of Malaria Host Interactions Unit at Swiss TPH

Email: Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser.

Plus d'informations et candidature: 

https://recruitingapp-2698.umantis.com/Vacancies/724/Description/2

 09 universite bordeauxLogo CNRS transparent

Project Title: 
Why and how trypanosomes build a flagellar pocket collar; a structure-function study

Project leader:
Dr Mélanie Bonhivers (Protist Parasite Cytoskeleton team, laboratory MFP UMR5234, University of Bordeaux/ CNRS)

Start of PhD project:
May-October 2021

Qualification and experience:
Expected skills
- General knowledge of cellular / molecular biology, cell culture
- General interest in cellular biology and parasitology
- Knowledge of fluorescence microscopy
- Expertise in super resolution microscopy, or electron microscopy or cryo-electron microscopy and image analysis would be an advantage.

- Rigor, experimental ethics
- Sense of organization, ability to manage multiple tasks in parallel
- Knowing how to work autonomously but in interaction with other members of the group
- Sense of teamwork
- Ability to adapt / Quickness of mind / strong motivation
- Understanding of written and oral English

Questions and applications ?
Send a full CV, a cover letter and the contact details of one or two referents to Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser.

Job description: 
pdfProfil_PhD_PRCI_ANR-FWF.pdf