Project Title : "Plasmodium falciparum: Characterization of novel enzymes responsible for the lipid processing pathway." Project PI : Cyrille Botté Co-PI : Dominique Mazier |
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BACKGROUND
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PUBLICATIONS Bansal, P., Antil, N., Kumar, M., Yamaryo-Botté, Y., Rawat, R.S., Pinto, S., Datta, K.K., Katris, N.J., Botté, C.Y., Prasad, T.S.K., Sharma, P., (2021). Protein kinase TgCDPK7 regulates vesicular trafficking and phospholipid synthesis in Toxoplasma gondii. PLoS Pathog [6.2] 17, e1009325. doi: 10.1371/journal.ppat.1009325 Katris, N.J., Yamaryo-Botte, Y., Janouškovec, J., Shunmugam, S., Arnold, C.-S., Yang, A.S.P., Vardakis, A., Stewart, R.J., Sauerwein, R., McFadden, G.I., Tonkin, C.J., Cesbron-Delauw, M.-F., Waller, Ross.F., Botte, C.Y., (2020). Rapid kinetics of lipid second messengers controlled by a cGMP signalling network coordinates apical complex functions in Toxoplasma tachyzoites. bioRxiv [preprint]. doi: 10.1101/2020.06.19.160341 Amiar, S., Katris, N.J., Berry, L., Dass, S., Duley, S., Arnold, C.-S., Shears, M.J., Brunet, C., Touquet, B., McFadden, G.I., Yamaryo-Botté, Y., Botté, C.Y., (2020). Division and Adaptation to Host Environment of Apicomplexan Parasites Depend on Apicoplast Lipid Metabolic Plasticity and Host Organelle Remodeling. Cell Rep [8.1] 30, 3778-3792.e9. doi: 10.1016/j.celrep.2020.02.072 Yang, L., Uboldi, A.D., Seizova, S., Wilde, M.L., Coffey, M.J., Katris, N.J., Yamaryo-Botte, Y., Kocan, M., Bathgate, R.A.D., Stewart, R.J., McConville, M.J., Thompson, P.E., Botte, C.Y., Tonkin, C.J., (2019). An apically located hybrid guanylate cyclase-ATPase is critical for the initiation of Ca(2+) signalling and motility in Toxoplasma gondii. J Biol Chem [4.1]. doi: 10.1074/jbc.RA118.005491 Dubois, D., S. Fernandes, S. Amiar, S. Dass, N. J. Katris, C. Y. Botte and Y. Yamaryo-Botte (2018). "Toxoplasma gondii acetyl-CoA synthetase is involved in fatty acid elongation (of long fatty acid chains) during tachyzoite life stages." J Lipid Res [4.8] 59(6): 994-1004. [Link] Uboldi, A. D., M. L. Wilde, E. A. McRae, R. J. Stewart, L. F. Dagley, L. Yang, N. J. Katris, S. V. Hapuarachchi, M. J. Coffey, A. M. Lehane, C. Y. Botte, R. F. Waller, A. I. Webb, M. J. McConville and C. J. Tonkin (2018). "Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii." PLoS Biol [9.2] 16(9): e2005642. [Link] |
The York Biomedical Research Institute (YBRI) are hosting an online live seminar on Friday 24th May 1-2pm BST as part of their biomedical science seminar series. You are all welcome to attend - registration is required via the...
[Communiqué] Congratulations to Arthur Talman, IRD Research Leader in the MIVEGEC laboratory (Montpellier), who has been awarded an Advanced Grant from the European Research Council (ERC) for the project "TROJAN - Molecular mimicry and immune...
Ana Rita Gomes, a CNRS Research Associate at the Laboratory of Pathogens and Host Immunity in Montpellier, and former Postdoctoral fellow of the LabEx ParaFrap, has been awarded the prestigious CNRS Bronze Medal in 2023. This...
. PhD Opportunity, Tours, France Supervision Thesis Supervisor: Sonia LAMANDE; Co-Supervisor: Julie TOTTEY Project: FUNTIONAL CHARACTERISATION OF CYSTEINE CATHEPSINS IN THE APICOMPLEXAN PARASITE CRYPTOSPORIDIUM...
Senior PostDoc position : computational biologist, Paris, France The ParSig team (https://research.pasteur.fr/en/team/molecular-parasitology-and-signaling) at the Institut Pasteur in Paris seeks for a highly...
Researcher in Livestock Immunology for the Study of Animal Trypanosomoses Through a One Health approach, the Intertryp Joint Research Unit (Cirad-IRD) is developing research on interactions between hosts,...
Happy New Year 2024! To kick off this new scientific year, here is the ParaFrap webinar schedule. Since January 2021, ParaFrap has been organizing a series of webinars. This monthly event, held every 2nd Thursday of the month, aims to strengthen...
PostDoc position : functional analysis of P. falciparum early gametocyte proteins, Allschwil, Switzerland The Malaria Gene Regulation Lab of Till Voss is looking for a highly motivated and talented postdoc to...
The team of Dr. Mohamed-Ali Hakimi, in collaboration with Isabelle Coppens (Johns Hopkins University Bloomberg School of Public Health and Malaria Research Institute, Baltimore, MD, USA), has developed a new (epi)genetic method to produce in vitro...
Success for ParaFrap students at MPM2023 Parafrap students won numerous awards at the MPM 2023, Woods Hole USA, 17-21 September 2023. A warm congratulations to all ! Parul Sharma (2nd year PhD under the...
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