Project Title : "Uncovering the function of two apicomplexan-specific histone acetylation marks located at the nucleosome dyad in both Toxoplasma and Theileria."

Project PI : Mohamed-Ali Hakimi  Co-PI : Gordon LANGSLEY

Thesis defense : 22/10/2020 

Lab : Host-pathogen interactions & Immunity to infections, IAB U1209-INSERM-CNRS, Université Grenoble Alpes

BACKGROUND

• MSc : M1 in Drug engineering, Biotechnology ⎜M2 in Cellular biology, physiology and epigenetics ⎜Grenoble, France
• BSc in biochemistry and biology  ⎜ Beyrouth, Lebanon

POSITION AFTER PARAFRAP TRAINING

Research Engineer, CNRS, Grenoble, France

PUBLICATIONS

Dard, C., Swale, C., Brenier-Pinchart, M.-P., Farhat, D.C., Bellini, V., Robert, M.G., Cannella, D., Pelloux, H., Tardieux, I., Hakimi, M.-A., (2021). A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection. BMC Biology [6.8] 19, 25. doi: 10.1186/s12915-021-00959-9

Farhat, D.C., Bowler, M.W., Communie, G., Pontier, D., Belmudes, L., Mas, C., Corrao, C., Coute, Y., Bougdour, A., Lagrange, T., Hakimi, M., Swale, C., (2021). A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental genes partitioning in Toxoplasma. bioRxiv [preprint] 2021.02.23.432502. doi: 10.1101/2021.02.23.432502

Farhat, D.C., Swale, C., Dard, C., Cannella, D., Ortet, P., Barakat, M., Sindikubwabo, F., Belmudes, L., De Bock, P.-J., Couté, Y., Bougdour, A., Hakimi, M.-A., (2020). A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment. Nat Microbiol [14.6] 1–14. doi: 10.1038/s41564-020-0674-4