Liste des Publications du LabEx
Les publications depuis le début du LabEx ParaFrap sont indiquées par année et par ordre alphabétique.
Les publications impliquant au moins deux partenaires du LabEx sont en couleur bleue.
Cliquez sur le lien doi pour accéder à la publication.
Le facteur d'impact est indiqué après le nom de chaque journal.
2012 ⎪ 2013 ⎪ 2014 ⎪ 2015 ⎪ 2016 ⎪ 2017 ⎪ 2018 ⎪ 2019 ⎪ 2020 ⎪ 2021 ⎪ 2022 ⎪ 2023 ⎪ 2024
Alencar, M.B., Girard, R.M.B.M., Crispim, M., Baptista, C.G., Biran, M., Bringaud, F., Silber, A.M., (2024). Elucidating the Transport Mechanisms and Metabolic Roles of Serine, Threonine, and Glycine in Trypanosoma cruzi. bioRxiv [preprint] 2024.06.29.601350. doi: 10.1101/2024.06.29.601350
Antunes, A.V., Shahinas, M., Swale, C., Farhat, D.C., Ramakrishnan, C., Bruley, C., Cannella, D., Robert, M.G., Corrao, C., Couté, Y., Hehl, A.B., Bougdour, A., Coppens, I., Hakimi, M.-A., (2024). In vitro production of cat-restricted Toxoplasma pre-sexual stages. Nature [50.5] 625, 366–376. doi: 10.1038/s41586-023-06821-y
Audibert, A., Mas-Orea, X., Rey, L., Belloy, M., Bassot, E., Marodon, G., Masson, F., Cenac, N., Dietrich, G., Bonnart, C., Blanchard, N., (2024). Toxoplasma gondii chronic infection decreases visceral nociception through peripheral opioid receptor signaling. bioRxiv [preprint] 2024.09.13.612908. doi: 10.1101/2024.09.13.612908
Baillou, A., Tomal, F., Chaumeil, T., Barc, C., Levern, Y., Sausset, A., Pezier, T., Schulthess, J., Peltier-Pain, P., Laurent, F., Lacroix-Lamandé, S., (2024). Characterization of intestinal mononuclear phagocyte subsets in young ruminants at homeostasis and during Cryptosporidium parvum infection. Front Immunol [7.3] 15. doi: 10.3389/fimmu.2024.1379798
Barrett, J.R., Silk, S.E., Mkindi, C.G., Kwiatkowska, K.M., Hou, M.M., Lias, A.M., Kalinga, W.F., Mtaka, I.M., McHugh, K., Bardelli, M., Davies, H., King, L.D.W., Edwards, N.J., Chauhan, V.S., Mukherjee, P., Rwezaula, S., Chitnis, C.E., Olotu, A.I., Minassian, A.M., Draper, S.J., Nielsen, C.M., (2024). Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens. Front Immunol [5.7] 14. doi: 10.3389/fimmu.2023.1193079/full
Belloy, M., Schmitt, B.A.M., Marty, F.H., Paut, C., Bassot-Parra, E., Amel, A., Alis, M., Ecalard, R., Boursereau, R., Gonzalez-Dunia, D., Blanchard, N., Suberbielle, E., (2024). Chronic IL-1-induced DNA double-strand break response in hippocampal neurons drives cognitive deficits. bioRxiv [preprint] 2024.02.03.578747. doi: 10.1101/2024.02.03.578747
Bitew, M.A., Gaete, P.S., Swale, C., Maru, P., Contreras, J.E., Saeij, J.P.J., (2024). Two Toxoplasma gondii putative pore-forming proteins, GRA47 and GRA72, influence small molecule permeability of the parasitophorous vacuole. mBio [6.4] 15, e03081-23. doi: 10.1128/mbio.03081-23
Cesar-Rodo, E., Dupouy, B., Häberli, C., Strub, J.-M., Williams, D.L., Mäser, P., Rottmann, M., Keiser, J., Lanfranchi, D.A., Davioud-Charvet, E., (2024). Regioselective Synthesis of Potential Non-Quinonoid Prodrugs of Plasmodione: Antiparasitic Properties Against Two Hemoglobin-Feeding Parasites and Drug Metabolism Studies. Molecules [4.2] 29, 5268. doi: 10.3390/molecules29225268
Charital, S., Lourdel, A., Quansah, N., Botté, C.Y., Yamaryo-Botté, Y., (2024a). Monitoring of Lipid Fluxes Between Host and Plastid-Bearing Apicomplexan Parasites, in: Maréchal, E. (Ed.), Plastids: Methods and Protocols [Book Chapter]. Springer US, New York, NY, pp. 197–204. doi: 10.1007/978-1-0716-3726-5_12
Charital, S., Shunmugam, S., Dass, S., Alazzi, A.M., Arnold, C.-S., Katris, N.J., Duley, S., Quansah, N.A., Pierrel, F., Govin, J., Yamaryo-Botté, Y., Botté, C.Y., (2024b). The acyl-CoA synthetase TgACS1 allows neutral lipid metabolism and extracellular motility in Toxoplasma gondii through relocation via its peroxisomal targeting sequence (PTS) under low nutrient conditions. mBio [6.4] 0, e00427-24. doi: 10.1128/mbio.00427-24
Coulibaly, A.S.K., Nozeran, L., Thomann, C., Alis, M., Bassot, E., Hassan, A., Porte, R., Belloy, M., Blanchard, N., Masson, F., (2024). Id2 levels determine the development of effector vs. exhausted tissue-resident memory CD8+ T cells during CNS chronic infection. bioRxiv [preprint] 2024.07.30.605547. doi: 10.1101/2024.07.30.605547
Das, S., Unhale, T., Marinach, C., Alegria, B. del C.V., Roux, C., Madry, H., Oumoussa, B.M., Amino, R., Iwanaga, S., Briquet, S., Silvie, O., (2024). Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei. bioRxiv [preprint] 2024.10.14.618196. doi: 10.1101/2024.10.14.618196
Dass, S., Shunmugam, S., Charital, S., Duley, S., Arnold, C.-S., Katris, N.J., Cavaillès, P., Cesbron-Delauw, M.-F., Yamaryo-Botté, Y., Botté, C.Y., (2024). Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation. Journal of Lipid Research 65. doi: 10.1016/j.jlr.2024.100645
Diaz-Barreiro, A., Cereghetti, G., Sánchez, F.G.O., Tonacini, J., Talabot-Ayer, D., Kieffer-Jaquinod, S., Kissling, V.M., Huard, A., Swale, C., Knowles, T.P.J., Couté, Y., Peter, M., Francés-Monerris, A., Palmer, G., (2024). Oxidation-sensitive cysteines drive IL-38 amyloid formation. Cell Rep [7.5] 43. doi: 10.1016/j.celrep.2024.114940
Diffendall, G., Claës, A., Barcons-Simon, A., Nyarko, P., Dingli, F., Santos, M., Loew, D., Claessens, A., Scherf, A., (2024). RNA polymerase III is involved in regulating Plasmodium falciparum virulence. eLife [6.4] 13. doi: 10.7554/eLife.95879.2
Diffendall, G., Scherf, A., (2024). Deciphering the Plasmodium falciparum perinuclear var gene expression site. Trends Parasitol [7.0] 40, 707–716. doi: 10.1016/j.pt.2024.06.002
Dinamarca, S., Croce, C., Salvioni, A., Garrido, F., Fidalgo, S.E., Bigliani, G., Mayorga, L.S., Blanchard, N., Cebrian, I., (2024). SNX17 Regulates Antigen Internalisation and Phagosomal Maturation by Dendritic Cells. Immunology [4.9]. doi: 10.1111/imm.13878
Dorin-Semblat, D., Semblat, J.-P., Hamelin, R., Srivastava, A., Tetard, M., Matesic, G., Doerig, C., Gamain, B., (2024). Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion. bioRxiv [preprint] 2024.07.08.602479. doi: 10.1101/2024.07.08.602479
Dupouy, B., Donzel, M., Roignant, M., Charital, S., Keumoe, R., Yamaryo-Botté, Y., Feckler, A., Bundschuh, M., Bordat, Y., Rottmann, M., Mäser, P., Botté, C.Y., Blandin, S.A., Besteiro, S., Davioud-Charvet, E., (2024). 3-Benzylmenadiones and their Heteroaromatic Analogues Target the Apicoplast of Apicomplexa Parasites: Synthesis and Bioimaging Studies. ACS Infect Dis [4.1] 10, 3553–3576. doi: 10.1021/acsinfecdis.4c00304
Gaucher, J., Montellier, E., Vial, G., Chuffart, F., Guellerin, M., Bouyon, S., Lemarie, E., Botté, Y.Y., Dirani, A., Ben Messaoud, R., Faure, M.J., Ribuot, D.G., Costentin, C., Tamisier, R., Botté, C.Y., Khochbin, S., Rousseaux, S., Pépin, J.-L., (2024). Long-term intermittent hypoxia in mice induces inflammatory pathways implicated in sleep apnea and steatohepatitis in humans. iScience [5.8] 108837. doi: 10.1016/j.isci.2024.108837
Gendron, T., Lanfranchi, D.A., Wenzel, N.I., Kessedjian, H., Jannack, B., Maes, L., Cojean, S., Müller, T.J.J., Loiseau, P.M., Davioud-Charvet, E., (2024). Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4H-tetrahydro-thiopyran-4-one S-Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones. Molecules [4.6] 29, 1620. doi: 10.3390/molecules29071620
Gharzeddine, K., Pietro, C.G., Malier, M., Hennot, C., Grespan, R., Yamaryo-Botté, Y., Botté, C.Y., Thomas, F., Laverriere, M.-H., Girard, E., Roth, G., Millet, A., (2024). Metabolic reprogramming of hypoxic tumor-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers. bioRxiv [preprint] 2024.02.22.581558. doi: 10.1101/2024.02.22.581558
Hellani, F., Leleu, I., Saidi, N., Martin, N., Lecoeur, C., Werkmeister, E., Koffi, D., Trottein, F., Yapo-Etté, H., Das, B., Abbadie, C., Pied, S., (2024). Role of astrocyte senescence regulated by the non– canonical autophagy in the neuroinflammation associated to cerebral malaria. Brain, Behavior, and Immunity 117, 20–35. doi: 10.1016/j.bbi.2023.12.030
Iacobucci, I., Monaco, V., Hovasse, A., Dupouy, B., Keumoe, R., Cichocki, B., Elhabiri, M., Meunier, B., Strub, J.-M., Monti, M., Cianférani, S., Blandin, S.A., Schaeffer-Reiss, C., Davioud-Charvet, E., (2024). Proteomic Profiling of Antimalarial Plasmodione Using 3-Benz(o)ylmenadione Affinity-Based Probes. ChemBioChem [2.6] e202400187. doi: 10.1002/cbic.202400187
Kumar, K., Crobu, L., Sterkers, Y., Prajapati, V.K., (2024). Apoptotic proteins in Leishmania donovani: In silico screening, modelling, and validation by knock-out and gene expression analysis. bioRxiv [preprint] 2024.04.05.588228. doi: 10.1101/2024.04.05.588228
Martinez, F.J., White, M., Guillotte-Blisnick, M., Huon, C., Boucharlat, A., Agou, F., England, P., Popovici, J., Hou, M.M., Silk, S.E., Barrett, J.R., Nielsen, C.M., Reimer, J.M., Mukherjee, P., Chauhan, V.S., Minassian, A.M., Draper, S.J., Chitnis, C.E., (2024). PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial. npj Vaccines [6.9] 9, 1–11. doi: 10.1038/s41541-023-00796-7
McLaughlin, E., Zavala Martinez, M.G., Dujeancourt-Henry, A., Chaze, T., Gianetto, Q.G., Matondo, M., Urbaniak, M.D., Glover, L., (2024). Phosphoproteomic analysis of the response to DNA damage in Trypanosoma brucei. Journal of Biological Chemistry 300, 107657. doi: 10.1016/j.jbc.2024.107657
Platon, L., Leroy, D., Fidock, D.A., Ménard, D., (2024). Drug-induced stress mediates Plasmodium falciparum ring-stage growth arrest and reduces in vitro parasite susceptibility to artemisinin. Microbiol Spectr [3.7] 0, e03500-23. doi: 10.1128/spectrum.03500-23
Porte, R., Belloy, M., Audibert, A., Bassot, E., Aïda, A., Alis, M., Miranda-Capet, R., Jourdes, A., Gisbergen, K. van, Masson, F., Blanchard, N., (2024). Protective function and differentiation cues of brain-resident CD8+ T cells during immune surveillance of chronic latent Toxoplasma gondii infection. bioRxiv [preprint] 2024.02.08.579453. doi: 10.1101/2024.02.08.579453
Quansah, N., Sarah, C., Yamaryo-Botté, Y., Botté, C.Y., (2024). Complex Endosymbiosis II: The Nonphotosynthetic Plastid of Apicomplexa Parasites (The Apicoplast) and Its Integrated Metabolism, in: Maréchal, E. (Ed.), Plastids: Methods and Protocols [Book Chapter]. Springer US, New York, NY, pp. 43–62. doi: 10.1007/978-1-0716-3726-5_3
Seveno, M., Loubens, M.N., Berry, L., Graindorge, A., Lebrun, M., Lavazec, C., Lamarque, M.H., (2024). The malaria parasite PP1 phosphatase controls the initiation of the egress pathway of asexual blood-stages by regulating the rounding-up of the vacuole. bioRxiv [preprint] 2024.07.30.605770. doi: 10.1101/2024.07.30.605770
Singh, P., Serizay, J., Couble, J., Cabahug, M.D., Rosa, C., Chen, P., Scherf, A., Koszul, R., Baumgarten, S., Bryant, J.M., (2024). Micro-C reveals MORC/ApiAP2-mediated links between distant, functionally related genes in the human malaria parasite. bioRxiv [preprint] 2024.08.28.610079. doi: 10.1101/2024.08.28.610079
Thiele, P.J., Mela-Lopez, R., Blandin, S.A., Klug, D., (2024). Let it glow: genetically encoded fluorescent reporters in Plasmodium. Malar J [3.0] 23, 114. doi: 10.1186/s12936-024-04936-9
Tottey, J., Etienne-Mesmin, L., Chalançon, S., Sausset, A., Denis, S., Mazal, C., Blavignac, C., Sallé, G., Laurent, F., Blanquet-Diot, S., Lacroix-Lamandé, S., (2024). Exploring the impact of digestive physicochemical parameters of adults and infants on the pathophysiology of Cryptosporidium parvum using the dynamic TIM-1 gastrointestinal model. Gut Pathog [4.3] 16, 55. doi: 10.1186/s13099-024-00648-2
Trometer, N., Pecourneau, J., Feng, L., Navarro-Huerta, J.A., Lazarin-Bidóia, D., de Oliveira Silva Lautenschlager, S., Maes, L., Fortes Francisco, A., Kelly, J.M., Meunier, B., Cal, M., Mäser, P., Kaiser, M., Davioud-Charvet, E., (2024). Synthesis and Anti-Chagas Activity Profile of a Redox-Active Lead 3-Benzylmenadione Revealed by High-Content Imaging. ACS Infect. Dis. doi: 10.1021/acsinfecdis.4c00137
Vigetti, L., Touquet, B., Debarre, D., Rose, T., Bureau, L., Abdallah, D., Dubacheva, G.V., Tardieux, I., (2024). Submicrometre spatiotemporal characterization of the Toxoplasma adhesion strategy for gliding motility. Nat Microbiol 1–17. doi: 10.1038/s41564-024-01818-3
Abebe, A., Bouyssou, I., Mabilotte, S., Dugassa, S., Assefa, A., Juliano, J.J., Lo, E., Menard, D., Golassa, L., (2023). Potential hidden Plasmodium vivax malaria reservoirs from low parasitemia Duffy-negative Ethiopians: Molecular evidence. PLoS Negl Trop Dis [4.8] 17, e0011326. doi: 10.1371/journal.pntd.0011326
Alloo, J., Leleu, I., Grangette, C., Pied, S., (2023). Parasite infections, neuroinflammation, and potential contributions of gut microbiota. Front Immunol [7.3] 13, 1024998. doi: 10.3389/fimmu.2022.1024998
Asencio, C., Hervé, P., Morand, P., Oliveres, Q., Morel, C.A., Prouzet-Mauleon, V., Biran, M., Monic, M., Bonhivers, M., Robinson, D.R., Ouellette, O., Riviere, L., Bringaud, F., Tetaud, E., (2023). Streptococcus pyogenes Cas9 ribonucleoprotein delivery for efficient, rapid and marker-free gene editing in Trypanosoma and Leishmania. bioRxiv [preprint] 2023.10.25.563974. doi: 10.1101/2023.10.25.563974
Baraka, V., Makenga, G., Francis, F., Kavishe, R.A., Minja, D.T., Ménard, D., (2023). PA-426 Genetic profiling of molecular markers of antimalarial resistance in areas targeted for school-based malaria chemoprevention strategies in North-Eastern, Tanzania. BMJ Glob Health [8.1] 8. doi: 10.1136/bmjgh-2023-EDC.196
Belhimeur, S., Briquet, S., Peronet, R., Pham, J., Commere, P.-H., Formaglio, P., Amino, R., Scherf, A., Silvie, O., Mecheri, S., (2023). Plasmodium-encoded murine IL-6 impairs liver stage infection and elicits long-lasting sterilizing immunity. Front Immunol [7.3] 14. doi: 10.3389/fimmu.2023.1143012
Bouyssou, I., Hoss, S.E., Doderer-Lang, C., Schoenhals, M., Rasoloharimanana, L.T., Vigan-Womas, I., Ratsimbasoa, A., Abate, A., Golassa, L., Mabilotte, S., Kessler, P., Guillotte-Blisnick, M., Martinez, F.J., Chitnis, C.E., Strouboulis, J., Ménard, D., (2023). Unveiling P. vivax invasion pathways in Duffy-negative individuals. Cell Host Microbe [31.3] 31, 2080-2092.e5. doi: 10.1016/j.chom.2023.11.007
Calvo-Alvarez, E., Ngoune, J.M.T., Sharma, P., Cooper, A., Camara, A., Travaillé, C., Crouzols, A., MacLeod, A., Rotureau, B., (2023). FLAgellum Member 8 modulates extravascular distribution of African trypanosomes. PLoS Pathog [7.4] 19, e1011220. doi: 10.1371/journal.ppat.1011220
Castellano, C.M., Lacroix, L., Mathis, E., Prorok, P., Hennion, M., Lopez-Rubio, J.-J., Méchali, M., Gomes, A.R., (2023). The genetic landscape of origins of replication in P. falciparum. Nucleic Acids Res [19.2] gkad1103. doi: 10.1093/nar/gkad1103
Chêne, A., Desrames, A., Tomlinson, A., Ruffié, C., Tangy, F., Gamain, B., (2023). An ACE2-Based Bimodular Fusion Protein Enables Reorientation of Endogenous Anti–Epstein-Barr Virus Antibodies Toward SARS-CoV-2 Spike. J Infect Dis [7.8] jiad329. doi: 10.1093/infdis/jiad329
Corucci, G., Batchu, K.C., Luchini, A., Santamaria, A., Frewein, M.P.K., Laux, V., Haertlein, M., Yamaryo-Botté, Y., Botté, C.Y., Sheridan, T., Tully, M., Maestro, A., Martel, A., Porcar, L., Fragneto, G., (2023). Developing advanced models of biological membranes with hydrogenous and deuterated natural glycerophospholipid mixtures. J Colloid Interf Sci [10.0] 645, 870–881. doi: 10.1016/j.jcis.2023.04.135
Dacheux, D., Martinez, G., Broster Reix, C.E., Beurois, J., Lores, P., Tounkara, M., Dupuy, J.-W., Robinson, D.R., Loeuillet, C., Lambert, E., Wehbe, Z., Escoffier, J., Amiri-Yekta, A., Daneshipour, A., Hosseini, S.-H., Zouari, R., Mustapha, S.F.B., Halouani, L., Jiang, X., Shen, Y., Liu, C., Thierry-Mieg, N., Septier, A., Bidart, M., Satre, V., Cazin, C., Kherraf, Z.E., Arnoult, C., Ray, P.F., Toure, A., Bonhivers, M., Coutton, C., (2023). Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function. eLife [7.7] 12, RP87698. doi: 10.7554/eLife.87698
Dechavanne, C., Dechavanne, S., Bosch, J., Metral, S., Redinger, K.R., Watson, Q.D., Ratsimbasoa, A.C., Roeper, B., Krishnan, S., Fong, R., Bennett, S., Carias, L., Chen, E., Salinas, N.D., Ghosh, A., Tolia, N.H., Woost, P.G., Jacobberger, J.W., Colin, Y., Gamain, B., King, C.L., Zimmerman, P.A., (2023). Duffy antigen is expressed during erythropoiesis in Duffy-negative individuals. Cell Host Microbe [31.3] 31, 2093-2106.e7. doi: 10.1016/j.chom.2023.10.019
Diffendall, G., Claës, A., Barcons-Simon, A., Nyarko, P., Dingli, F., Loew, D., Claessens, A., Scherf, A., (2023). RNA polymerase III is involved in regulating Plasmodium falciparum virulence. bioRxiv [preprint] 2023.07.18.549525. doi: 10.1101/2023.07.18.549525
Dobrescu, I., Hammam, E., Dziekan, J.M., Claës, A., Halby, L., Preiser, P., Bozdech, Z., Arimondo, P.B., Scherf, A., Nardella, F., (2023). Plasmodium falciparum Eukaryotic Translation Initiation Factor 3 is Stabilized by Quinazoline-Quinoline Bisubstrate Inhibitors. ACS Infect Dis [5.3] 9, 1257–1266. doi: 10.1021/acsinfecdis.3c00127
Doritchamou, J., Nielsen, M.A., Chêne, A., Viebig, N.K., Lambert, L.E., Sander, A.F., Semblat, J.-P., Hundt, S., Orr-Gonzalez, S., Janitzek, C.M., Spiegel, A.J., Clemmensen, S.B., Thomas, M.L., Nason, M.C., Snow-Smith, M., Barnafo, E.K., Shiloach, J., Chen, B.B., Nadakal, S., Highsmith, K., Ouahes, T., Conteh, S., Sharma, A., Torano, H., Butler, B., Reiter, K., Rausch, K.M., Scaria, P.V., Anderson, C., Narum, D.L., Salanti, A., Fried, M., Theander, T.G., Gamain, B., Duffy, P.E., (2023). Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA. Lab Anim [6.9] 1–9. doi: 10.1038/s41684-023-01274-2
Fernandes, P., Loubens, M., Marinach, C., Coppée, R., Baron, L., Grand, M., Andre, T.-P., Hamada, S., Langlois, A.-C., Briquet, S., Bun, P., Silvie, O., (2023). Plasmodium sporozoites require the protein B9 to invade hepatocytes. iScience [6.1] 26, 106056. doi: 10.1016/j.isci.2023.106056
Green, E., Jaouen, E., Klug, D., Olmo, R.P., Gautier, A., Blandin, S., Marois, E., (2023). A population modification gene drive targeting both Saglin and Lipophorin impairs Plasmodium transmission in Anopheles mosquitoes. bioRxiv [preprint] 2022.07.08.499187. doi: 10.1101/2022.07.08.499187
Hervé, P., Monic, S., Bringaud, F., Rivière, L., (2023). Phospholipases A and Lysophospholipases in protozoan parasites. Microb Cell [4.6] 10, 204–216. doi: 10.15698/mic2023.10.805
Hou, M.M., Barrett, J.R., Themistocleous, Y., Rawlinson, T.A., Diouf, A., Martinez, F.J., Nielsen, C.M., Lias, A.M., King, L.D.W., Edwards, N.J., Greenwood, N.M., Kingham, L., Poulton, I.D., Khozoee, B., Goh, C., Hodgson, S.H., Mac Lochlainn, D.J., Salkeld, J., Guillotte-Blisnick, M., Huon, C., Mohring, F., Reimer, J.M., Chauhan, V.S., Mukherjee, P., Biswas, S., Taylor, I.J., Lawrie, A.M., Cho, J.-S., Nugent, F.L., Long, C.A., Moon, R.W., Miura, K., Silk, S.E., Chitnis, C.E., Minassian, A.M., Draper, S.J., (2023). Vaccination with Plasmodium vivax Duffy-binding protein inhibits parasite growth during controlled human malaria infection. Sci Transl Med [19.3] 15, eadf1782. doi: 10.1126/scitranslmed.adf1782
Issa, M.S., Warsame, M., Mahamat, M.H.T., Saleh, I.D.M., Boulotigam, K., Djimrassengar, H., Issa, A.H., Abdelkader, O., Hassoumi, M., Djimadoum, M., Doderer-Lang, C., Ndihiokubwayo, J.B., Rasmussen, C., Menard, D., (2023). Therapeutic efficacy of artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Chad: clinical and genetic surveillance. Malar J [3.5] 22, 240. doi: 10.1186/s12936-023-04644-w
Iuso, D., Garcia-Saez, I., Couté, Y., Yamaryo-Botté, Y., Boeri Erba, E., Adrait, A., Zeaiter, N., Tokarska-Schlattner, M., Jilkova, Z.M., Boussouar, F., Barral, S., Signor, L., Couturier, K., Hajmirza, A., Chuffart, F., Bourova-Flin, E., Vitte, A.-L., Bargier, L., Puthier, D., Decaens, T., Rousseaux, S., Botté, C., Schlattner, U., Petosa, C., Khochbin, S., (2023). Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet. Sci Adv [15.0] 9, eadh0140. doi: 10.1126/sciadv.adh0140
Jhingan, G.D., Manich, M., Olivo-Marin, J.-C., Guillen, N., (2023). Live Cells Imaging and Comparative Phosphoproteomics Uncover Proteins from the Mechanobiome in Entamoeba histolytica. Int J Mol Sci [6.2] 24, 8726. doi: 10.3390/ijms24108726
Juban, P., Bart, J.-M., Segard, A., Jamonneau, V., Ravel, S., (2023). Trypanosoma brucei gambiense group 2 experimental in vivo life cycle: from procyclic to bloodstream form. bioRxiv [preprint]. doi: 10.1101/2023.10.19.562698
Klug, D., Blandin, S.A., (2023). Activation of complement-like antiparasitic responses in Anopheles mosquitoes. Curr Opin Microbiol [7.6] 72, 102280. doi: 10.1016/j.mib.2023.102280
Klug, D., Gautier, A., Calvo, E., Marois, E., Blandin, S.A., (2023). The salivary protein Saglin facilitates efficient midgut colonization of Anopheles mosquitoes by malaria parasites. PLoS Pathog [7.4] 19, e1010538. doi: 10.1371/journal.ppat.1010538
Krishnamurthy, S., Maru, P., Wang, Y., Bitew, M.A., Mukhopadhyay, D., Yamaryo-Botté, Y., Paredes-Santos, T.C., Sangaré, L.O., Swale, C., Botté, C.Y., Saeij, J.P.J., (2023). CRISPR Screens Identify Toxoplasma Genes That Determine Parasite Fitness in Interferon Gamma-Stimulated Human Cells. mBio [7.8] 0, e00060-23. doi: 10.1128/mbio.00060-23
Loubens, M., Marinach, C., Paquereau, C.-E., Hamada, S., Hoareau-Coudert, B., Akbar, D., Franetich, J.-F., Silvie, O., (2023). The claudin-like apicomplexan microneme protein is required for gliding motility and infectivity of Plasmodium sporozoites. PLoS Pathog [7.4] 19, e1011261. doi: 10.1371/journal.ppat.1011261
Martinez, F.J., Guillotte-Blisnick, M., Huon, C., England, P., Popovici, J., Laude, H., Arowas, L., Ungeheuer, M.-N., Reimer, J.M., Carter, D., Reed, S., Mukherjee, P., Chauhan, V.S., Chitnis, C.E., (2023). Immunogenicity of a Plasmodium vivax vaccine based on the duffy binding protein formulated using adjuvants compatible for use in humans. Sci Rep [5.0] 13, 13904. doi: 10.1038/s41598-023-40043-6
Mihreteab, S., Platon, L., Berhane, A., Stokes, B.H., Warsame, M., Campagne, P., Criscuolo, A., Ma, L., Petiot, N., Doderer-Lang, C., Legrand, E., Ward, K.E., Zehaie Kassahun, A., Ringwald, P., Fidock, D.A., Ménard, D., (2023). Increasing Prevalence of Artemisinin-Resistant HRP2-Negative Malaria in Eritrea. New Engl J Med [158.5] 389, 1191–1202. doi: 10.1056/NEJMoa2210956
Minet, C., Chantal, I., Berthier, D., (2023). Recent advances in genome editing of bloodstream forms of Trypanosoma congolense using CRISPR-Cas9 ribonucleoproteins: Proof of concept. Exp Parasitol [2.1] 252, 108589. doi: 10.1016/j.exppara.2023.108589
Najm, R., Ruivo, M.T.G., Penarete-Vargas, D.M., Hamie, M., Mouveaux, T., Gissot, M., Boulanger, M.J., El Hajj, H., Lebrun, M., (2023). Invasion of Toxoplasma gondii bradyzoites: Molecular dissection of the moving junction proteins and effective vaccination targets. Proc Natl Acad Sci U S A [12.8] 120, e2219533120. doi: 10.1073/pnas.2219533120
Nardella, F., Dobrescu, I., Hassan, H., Rodrigues, F., Thiberge, S., Silva, L.M., Tafit, A., Jallet, C., Cadet-Daniel, V., Goussin, S., Lorthiois, A., Menon, Y., Molinier, N., Pechalrieu, D., Long, C., Sautel, F., Matondo, M., Duchateau, M., Médard, G., Witkowski, B., Scherf, A., Halby, L., Arimondo, P.B., (2023). Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug resistant Plasmodium falciparum. iScience [6.1] 105940. doi: 10.1016/j.isci.2023.105940
N’Dri, M.-E., Tavella, T.A., Royer, L., Dupuy, F., Bedault, L., Verdier, F., Lavazec, C., (2023). Phosphodiesterase delta governs the mechanical properties of erythrocytes infected with Plasmodium falciparum gametocytes. Microbes Infect [9.6] 105102. doi: 10.1016/j.micinf.2023.105102
Ngou, C.M., Bayibéki, A.N., Abate, L., Makinde, O.S., Feufack-Donfack, L.B., Sarah-Matio, E.M., Bouopda-Tuedom, A.G., Taconet, P., Moiroux, N., Awono-Ambéné, P.H., Talman, A., Ayong, L.S., Berry, A., Nsango, S.E., Morlais, I., (2023). Influence of the sickle cell trait on Plasmodium falciparum infectivity from naturally infected gametocyte carriers. BMC Infect Dis [3.7] 23, 317. doi: 10.1186/s12879-023-08134-x
Ngoune, J.M.T., Sharma, P., Crouzols, A., Rotureau, B., (2023). Stumpy forms are the predominant transmissible forms of Trypanosoma brucei. bioRxiv [preprint] 2023.08.30.555461. doi: 10.1101/2023.08.30.555461
Paredes-Santos, T.C., Bitew, M.A., Swale, C., Rodriguez, F., Krishnamurthy, S., Wang, Y., Maru, P., Sangaré, L.O., Saeij, J.P.J., (2023). Genome-wide CRISPR screen identifies genes synthetically lethal with GRA17, a nutrient channel encoding gene in Toxoplasma. PLoS Pathog [6.7] 19, e1011543. doi: 10.1371/journal.ppat.1011543
Peylhard, M., Berthier, D., Dayo, G.-K., Chantal, I., Sylla, S., Nidelet, S., Dubois, E., Martin, G., Sempéré, G., Flori, L., Thévenon, S., (2023). Whole blood transcriptome profiles of trypanotolerant and trypanosusceptible cattle highlight a differential modulation of metabolism and immune response during infection by Trypanosoma congolense. Peer Community Journal [no IF] 3. doi: 10.24072/pcjournal.239
Platon, L., Zhang, Q., Cao, J., Ménard, D., (2023). Malaria in the horn of Africa: The ongoing battle against drug resistance. Clin Transl Med [8.6] 13, e1482. doi: 10.1002/ctm2.1482
Rosa, C., Singh, P., Chen, P., Sinha, A., Claës, A., Preiser, P.R., Dedon, P.C., Baumgarten, S., Scherf, A., Bryant, J.M., (2023). Cohesin contributes to transcriptional repression of stage-specific genes in the human malaria parasite. EMBO reports [9.4] 24, e57090. doi: 10.15252/embr.202357090
Saidi, N., Blaizot, R., Prévot, G., Aoun, K., Demar, M., Cazenave, P.A., Bouratbine, A., Pied, S., (2023). Clinical and immunological spectra of human cutaneous leishmaniasis in North Africa and French Guiana. Front Immunol [7.3] 14. doi: 10.3389/fimmu.2023.1134020
Sanchez, S.G., Bassot, E., Cerutti, A., Mai Nguyen, H., Aïda, A., Blanchard, N., Besteiro, S., (2023). The apicoplast is important for the viability and persistence of Toxoplasma gondii bradyzoites. Proc Natl Acad Sci U S A [12.8] 120, e2309043120. doi: 10.1073/pnas.2309043120
Sene, S.D., Pouye, M.N., Martins, R.M., Diallo, F., Mangou, K., Bei, A.K., Barry, A., Faye, Oumar, Ndiaye, O., Faye, Ousmane, Sall, A.A., Lopez-Rubio, J.-J., Mbengue, A., (2023). Identification of an in vitro artemisinin-resistant Plasmodium falciparum kelch13 R515K mutant parasite in Senegal. Front Parasitol [no IF] 2. doi: 10.3389/fpara.2023.1076759
Sheokand, P.K., Yamaryo-Botté, Y., Narwal, M., Arnold, C.-S., Thakur, V., Islam, M.M., Banday, M.M., Asad, M., Botté, C.Y., Mohmmed, A., (2023). A Plasmodium falciparum lysophospholipase regulates host fatty acid flux via parasite lipid storage to enable controlled asexual schizogony. Cell Rep [10.0] 112251. doi: 10.1016/j.celrep.2023.112251
Shunmugam, S., Quansah, N., Flammersfeld, A., Islam, M.M., Sassmannshausen, J., Bennink, S., Yamaryo-Botté, Y., Pradel, G., Botté, C.Y., (2023). The patatin-like phospholipase PfPNPLA2 is involved in the mitochondrial degradation of phosphatidylglycerol during Plasmodium falciparum blood stage development. Front Cell Infect Microbiol [6.1] 13.
Swale, C., Hakimi, M.-A., (2023). 3′-end mRNA processing within apicomplexan parasites, a patchwork of classic, and unexpected players. WIREs RNA [9.3] n/a, e1783. doi: 10.1002/wrna.1783
Taleva, G., Husová, M., Panicucci, B., Hierro-Yap, C., Pineda, E., Biran, M., Moos, M., Šimek, P., Butter, F., Bringaud, F., Zíková, A., (2023). Mitochondrion of the Trypanosoma brucei long slender bloodstream form is capable of ATP production by substrate-level phosphorylation. PLoS Pathog [7.4] 19, e1011699. doi: 10.1371/journal.ppat.1011699
Tomal, F., Sausset, A., Le Vern, Y., Sedano, L., Techer, C., Lacroix-Lamandé, S., Laurent, F., Silvestre, A., Bussière, F.I., (2023). Microbiota promotes recruitment and pro-inflammatory response of caecal macrophages during E. tenella infection. Gut Pathog [5.3] 15, 65. doi: 10.1186/s13099-023-00591-8
Trometer, N., Cichocki, B., Chevalier, Q., Pécourneau, J., Strub, J.-M., Hemmerlin, A., Specht, A., Davioud-Charvet, E., Elhabiri, M., (2023). Synthesis and Photochemical Properties of Fluorescent Metabolites Generated from Fluorinated Benzoylmenadiones in Living Cells. J Org Chem [4.2]. doi: 10.1021/acs.joc.3c00620
Vats, K., Tandon, R., Roshanara, Beg, Mirza.A., Corrales, R.M., Yagoubat, A., Reyaz, E., Wani, Tasaduq.H., Baig, Mirza.S., Chaudhury, A., Krishnan, A., Puri, N., Salotra, P., Sterkers, Y., Selvapandiyan, A., (2023). Interaction of novel proteins, centrin4 and protein of centriole in Leishmania parasite and their effects on the parasite growth. BBA - Mol Cell Res [5.0] 1870, 119416. doi: 10.1016/j.bbamcr.2022.119416
Wagner, M.P., Chitnis, C.E., (2023). Lipid peroxidation and its repair in malaria parasites. Trends Parasitol [10.5]. doi: 10.1016/j.pt.2022.12.006
Yade, M.S., Dièye, B., Coppée, R., Mbaye, A., Diallo, M.A., Diongue, K., Bailly, J., Mama, A., Fall, A., Thiaw, A.B., Ndiaye, I.M., Ndiaye, T., Gaye, A., Tine, A., Diédhiou, Y., Mbaye, A.M., Doderer-Lang, C., Garba, M.N., Bei, A.K., Ménard, D., Ndiaye, D., (2023a). Ex vivo RSA and pfkelch13 targeted-amplicon deep sequencing reveal parasites susceptibility to artemisinin in Senegal, 2017. Malar J [3.5] 22, 167. doi: 10.1186/s12936-023-04588-1
Yade, M.S., Fall, A., Coppée, R., Mbaye, A., Adoux, L., Diallo, M.A., Diongue, K., Tine, A., Mama, A., Thiaw, A.B., Bailly, J., Ndiaye, I.M., Kébé, O., Sow, D., Ndiaye, T., Diédhiou, Y., Gaye, A., Doderer-Lang, C., Niyomwungere, D., Tarama, C.W., Garba, M.N., Bei, A.K., Dièye, B., Ménard, D., Ndiaye, D., (2023b). Ex vivo susceptibility and molecular signature assessment of antimalarial-based combination therapies (ACT) partner drugs resistance in Senegal. Research Square [preprint]. doi: 10.21203/rs.3.rs-3146514/v1
Yogavel, M., Bougdour, A., Mishra, S., Malhotra, N., Chhibber-Goel, J., Bellini, V., Harlos, K., Laleu, B., Hakimi, M.-A., Sharma, A., (2023). Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. PLoS Pathog [7.4] 19, e1011124. doi: 10.1371/journal.ppat.1011124
Albisetti, A., Venugopal, K., Guérin, A., (2022). New frontiers in host‐parasite interactions, from cell to organism. Mol Microbiol [4.0] mmi.15013. 10.1111/mmi.15013
Ashraf, K., Tajeri, S., Arnold, C.-S., Amanzougaghene, N., Franetich, J.-F., Vantaux, A., Soulard, V., Bordessoulles, M., Cazals, G., Bousema, T., Gemert, G.-J. van, Grand, R.L., Dereuddre-Bosquet, N., Barale, J.-C., Witkowski, B., Snounou, G., Duval, R., Botté, C.Y., Mazier, D., (2022). Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites. Life Sci Alliance [4.6] 5. doi: 10.26508/lsa.202101237
Barbieri, D., Gomez, L., Royer, L., Dupuy, F., Franetich, J.-F., Tefit, M., N’Dri, M.-E., Mazier, D., Silvie, O., Moreno-Sabater, A., Lavazec, C., (2022). The Phosphodiesterase Inhibitor Tadalafil Promotes Splenic Retention of Plasmodium falciparum Gametocytes in Humanized Mice. Front Cell Infect Microbiol [5.3] 12. doi: 10.3389/fcimb.2022.883759
Bouabid, C., Yamaryo-Botté, Y., Rabhi, S., Bichiou, H., Hkimi, C., Bouglita, W., Chaouach, M., Eddaikra, N., Ghedira, K., Guizani-Tabbane, L., Botté, C.Y., Rabhi, I., (2022). Fatty Acid Profiles of Leishmania major Derived from Human and Rodent Hosts in Endemic Cutaneous Leishmaniasis Areas of Tunisia and Algeria. Pathogens [3.5] 11, 92. doi: 10.3390/pathogens11010092
Bouyssou, I., Martínez, F.J., Campagne, P., Ma, L., Doderer-Lang, C., Chitnis, C.E., Ménard, D., (2022). Plasmodium vivax blood stage invasion pathways: Contribution of omics technologies in deciphering molecular and cellular mechanisms. C R Biol [2.4] 345, 1–43. doi: 10.5802/crbiol.95
Chopin, N., Bosson, J., Iikawa, S., Picot, S., Bienvenu, A.-L., Lavoignat, A., Bonnot, G., Riou, M., Beaugé, C., Guillory, V., Biot, C., Pilet, G., Chessé, M., Davioud-Charvet, E., Elhabiri, M., Bouillon, J.-P., Médebielle, M., (2022). Evaluation of ferrocenyl-containing γ-hydroxy-γ-lactam-derived tetramates as potential antiplasmodials. Eur J Med Chem [7.1] 243, 114735. doi: 10.1016/j.ejmech.2022.114735
Cova, M.M., Lamarque, M.H., Lebrun, M., (2022). How Apicomplexa Parasites Secrete and Build Their Invasion Machinery. Annu Rev Microbiol [16.2] 76, 619–640. doi: 10.1146/annurev-micro-041320-021425
Croce, C., Garrido, F., Dinamarca, S., Santi-Rocca, J., Marion, S., Blanchard, N., Mayorga, L.S., Cebrian, I., (2022). Efficient Cholesterol Transport in Dendritic Cells Defines Optimal Exogenous Antigen Presentation and Toxoplasma gondii Proliferation. Front Cell Dev Biol [6.7] 10. doi: 10.3389/fcell.2022.837574
Diffendall, G.M., Barcons-Simon, A., Baumgarten, S., Dingli, F., Loew, D., Scherf, A., (2022). Discovery of RUF6 ncRNA–interacting proteins involved in P. falciparum immune evasion. Life Sci Alliance [5.8] 6. doi: 10.26508/lsa.202201577
Doritchamou, J.Y.A., Nielsen, M.A., Chene, A., VIebig, N.K., Lambert, L.E., Sander, A.F., Semblat, J.-P., Hundt, S., Orr-Gonzalez, S., Janitzek, C.M., Spiegel, A.J., Clemmensen, S.B., Thomas, M.L., Nason, M.C., Snow-Smith, M., Barnafo, E.K., Shiloach, J., Chen, B.B., Nadakal, S., Highsmith, K., Ouahes, T., Conteh, S., Sharma, A., Torano, H., Butler, B., Reiter, K., Rausch, K.M., Scaria, P.V., Anderson, C., Narum, D.L., Salanti, A., Fried, M., Theander, T.G., Gamain, B., Duffy, P.E., (2022). Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA. bioRxiv [preprint] 2022.06.24.497389. doi: 10.1101/2022.06.24.497389
Fernandes, P., Loubens, M., Le Borgne, R., Marinach, C., Ardin, B., Briquet, S., Vincensini, L., Hamada, S., Hoareau-Coudert, B., Verbavatz, J.-M., Weiner, A., Silvie, O., (2022). The AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts. PLoS Pathog [6.8] 18, e1010643. doi: 10.1371/journal.ppat.1010643
Fréville, A., Gnangnon, B., Tremp, A.Z., De Witte, C., Cailliau, K., Martoriati, A., Aliouat, E.M., Fernandes, P., Chhuon, C., Silvie, O., Marion, S., Guerrera, I.C., Dessens, J.T., Pierrot, C., Khalife, J., (2022). Plasmodium berghei leucine-rich repeat protein 1 downregulates protein phosphatase 1 activity and is required for efficient oocyst development. Open Biol [7.0] 12, 220015. doi: 10.1098/rsob.220015
Guillén, N., (2022). Pathogenicity and virulence of Entamoeba histolytica, the agent of amoebiasis. Virulence [5.4]. 10.1080/21505594.2022.2158656
Hakimi, M.-A., (2022). Epigenetic Reprogramming in Host-Parasite Coevolution: The Toxoplasma Paradigm. Annu Rev Microbiol [15.5] 76, annurev-micro-041320-011520. doi: 10.1146/annurev-micro-041320-011520
Hassan, A., Blanchard, N., (2022). Microbial (co)infections: Powerful immune influencers. PLoS Pathog [6.8] 18, e1010212. doi: 10.1371/journal.ppat.1010212
Keita, A., Franetich, J.-F., Carraz, M., Valentin, L., Bordessoules, M., Baron, L., Bigeard, P., Dupuy, F., Geay, V., Tefit, M., Sarrasin, V., Michel, S., Lavazec, C., Houzé, S., Mazier, D., Soulard, V., Porée, F.-H., Duval, R., (2022). Potent Antiplasmodial Derivatives of Dextromethorphan Reveal the Ent-Morphinan Pharmacophore of Tazopsine-Type Alkaloids. Pharmaceutics [6.3] 14, 372. doi: 10.3390/pharmaceutics14020372
Klug, D., Arnold, K., Mela-Lopez, R., Marois, E., Blandin, S.A., (2022). A toolbox of engineered mosquito lines to study salivary gland biology and malaria transmission. PLoS Pathog [6.8] 18, e1010881. doi: 10.1371/journal.ppat.1010881
Koko, V.S., Warsame, M., Vonhm, B., Jeuronlon, M.K., Menard, D., Ma, L., Taweh, F., Tehmeh, L., Nyansaiye, P., Pratt, O.J., Parwon, S., Kamara, P., Asinya, M., Kollie, A., Ringwald, P., (2022). Artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular markers. Malaria J [2.9] 21, 134. doi: 10.1186/s12936-022-04140-7
Leleu, I., Alloo, J., Cazenave, P.-A., Roland, J., Pied, S., (2022). Autophagy Pathways in the Genesis of Plasmodium-Derived Microvesicles: A Double-Edged Sword? Life [3.8] 12, 415. doi: 10.3390/life12030415
Luiza-Batista, C., Thiberge, S., Serra-Hassoun, M., Nardella, F., Claës, A., Nicolete, V.C., Commère, P.-H., Mancio-Silva, L., Ferreira, M.U., Scherf, A., Garcia, S., (2022). Humanized mice for investigating sustained Plasmodium vivax blood-stage infections and transmission. Nat Commun [17.7] 13, 4123. doi: 10.1038/s41467-022-31864-6
Mama, A., Ahiabor, C., Tornyigah, B., Frempong, N.A., Kusi, K.A., Adu, B., Courtin, D., Houzé, S., Deloron, P., Ofori, M.F., Anang, A.K., Ariey, F., Ndam, N.T., (2022). Intermittent preventive treatment in pregnancy with sulfadoxine–pyrimethamine and parasite resistance: cross-sectional surveys from antenatal care visit and delivery in rural Ghana. Malar J [3.0] 21, 107. doi: 10.1186/s12936-022-04124-7
Manickam, Y., Malhotra, N., Mishra, S., Babbar, P., Dusane, A., Laleu, B., Bellini, V., Hakimi, M.-A., Bougdour, A., Sharma, A., (2022). Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development. PLoS Pathog [6.8] 18, e1010363. doi: 10.1371/journal.ppat.1010363
Monic, S.G., Lamy, A., Thonnus, M., Bizarra-Rebelo, T., Bringaud, F., Smith, T.K., Figueiredo, L.M., Rivière, L., (2022). A novel lipase with dual localisation in Trypanosoma brucei. Sci Rep [4.4] 12, 4766. doi: 10.1038/s41598-022-08546-w
Mwakasungula, S., Rougeron, V., Arnathau, C., Boundenga, L., Miguel, E., Boissière, A., Jiolle, D., Durand, P., Msigwa, A., Mswata, S., Olotu, A., Sterkers, Y., Roche, B., Killeen, G., Cerqueira, F., Bitome-Essono, P.Y., Bretagnolle, F., Masanja, H., Paupy, C., Sumaye, R., Prugnolle, F., (2022). Using hematophagous fly blood meals to study the diversity of blood-borne pathogens infecting wild mammals. Mol Ecol Resour [7.1]. doi: 10.1111/1755-0998.13670
Najm, R., Hamie, M., Berry-Sterkers, L., Lebrun, M., El Hajj, H., Lamarque, M.H., (2022). Toxoplasma Shelph, a Phosphatase Located in the Parasite Endoplasmic Reticulum, Is Required for Parasite Virulence. mSphere [5.0] e00350-22. doi: 10.1128/msphere.00350-22
Negreira, G.H., Monsieurs, P., Imamura, H., Maes, I., Kuk, N., Yagoubat, A., Van den Broeck, F., Sterkers, Y., Dujardin, J.-C., Domagalska, M.A., (2022). High throughput single-cell genome sequencing gives insights into the generation and evolution of mosaic aneuploidy in Leishmania donovani. Nucleic Acids Res [17.0] 50, 293–305. doi: 10.1093/nar/gkab1203
Nofal, S.D., Dominicus, C., Broncel, M., Katris, N.J., Flynn, H.R., Arrizabalaga, G., Botté, C.Y., Invergo, B.M., Treeck, M., (2022). A positive feedback loop mediates crosstalk between calcium, cyclic nucleotide and lipid signalling in calcium-induced Toxoplasma gondii egress. PLoS Pathog [6.8] 18, e1010901. doi: 10.1371/journal.ppat.1010901
Perdomo, D., Berdance, E., Lallinger-Kube, G., Sahin, A., Dacheux, D., Landrein, N., Cayrel, A., Ersfeld, K., Bonhivers, M., Kohl, L., Robinson, D.R., (2022). TbKINX1B: a novel BILBO1 partner and an essential protein in bloodstream form Trypanosoma brucei. Parasite [3.0] 29, 14. doi: 10.1051/parasite/2022015
Peylhard, M., Berthier, D., Dayo, G.-K., Chantal, I., Sylla, S., Nidelet, S., Dubois, E., Martin, G., Sempéré, G., Flori, L., Thévenon, S., (2022). Whole blood transcriptome profiles of trypanotolerant and trypanosusceptible cattle highlight a differential modulation of metabolism and immune response during infection by Trypanosoma congolense. Peer Community Journal [no IF] 3. doi: 10.24072/pcjournal.239
Piel, L., Rajan, K.S., Bussotti, G., Varet, H., Legendre, R., Proux, C., Douché, T., Giai-Gianetto, Q., Chaze, T., Cokelaer, T., Vojtkova, B., Gordon-Bar, N., Doniger, T., Cohen-Chalamish, S., Rengaraj, P., Besse, C., Boland, A., Sadlova, J., Deleuze, J.-F., Matondo, M., Unger, R., Volf, P., Michaeli, S., Pescher, P., Späth, G.F., (2022). Experimental evolution links post-transcriptional regulation to Leishmania fitness gain. PLoS Pathog [6.8] 18, e1010375. 10.1371/journal.ppat.1010375
Pissarra, J., Dorkeld, F., Loire, E., Bonhomme, V., Sereno, D., Lemesre, J.-L., Holzmuller, P., (2022). SILVI, an open-source pipeline for T-cell epitope selection. PLoS One [3.2] 17, e0273494. doi: 10.1371/journal.pone.0273494
Ramanantsalama, M.R., Landrein, N., Casas, E., Salin, B., Blancard, C., Bonhivers, M., Robinson, D.R., Dacheux, D., (2022). TFK1, a basal body transition fibre protein that is essential for cytokinesis in Trypanosoma brucei. J Cell Sci [5.3] jcs.259893. doi: 10.1242/jcs.259893
Real, E., Nardella, F., Scherf, A., Mancio-Silva, L., (2022). Repurposing of Plasmodium falciparum var genes beyond the blood stage. Curr Opin Microbiol [7.6] 70, 102207. doi: 10.1016/j.mib.2022.102207
Renaud, E.A., Pamukcu, S., Cerutti, A., Berry, L., Lemaire-Vieille, C., Yamaryo-Botté, Y., Botté, C.Y., Besteiro, S., (2022). Disruption of the plastid-hosted iron-sulfur cluster biogenesis pathway in Toxoplasma gondii has pleiotropic effects irreversibly impacting parasite viability. J Biol Chem [5.5]. 298, 102243. doi: 10.1016/j.jbc.2022.102243
Roumégous, C., Abou Hammoud, A., Fuster, D., Dupuy, J.-W., Blancard, C., Salin, B., Robinson, D.R., Renesto, P., Tardieux, I., Frénal, K., (2022). Identification of new components of the basal pole of Toxoplasma gondii provides novel insights into its molecular organization and functions. Front Cell Infect Microbiol [6.1] 12, 1010038. doi: 10.3389/fcimb.2022.1010038
Shunmugam, S., Arnold, C.-S., Dass, S., Katris, N.J., Botté, C.Y., (2022). The flexibility of Apicomplexa parasites in lipid metabolism. PLoS Pathog [6.8] 18, e1010313. doi: 10.1371/journal.ppat.1010313
Silvestre, A., Shintre, S.S., Rachidi, N., (2022). Released Parasite-Derived Kinases as Novel Targets for Antiparasitic Therapies. Front Cell Infect Microbiol [5.3] 12, 825458. doi: 10.3389/fcimb.2022.825458
Sparvoli, D., Delabre, J., Penarete‐Vargas, D.M., Kumar Mageswaran, S., Tsypin, L.M., Heckendorn, J., Theveny, L., Maynadier, M., Mendonça Cova, M., Berry‐Sterkers, L., Guérin, A., Dubremetz, J., Urbach, S., Striepen, B., Turkewitz, A.P., Chang, Y., Lebrun, M., (2022). An apical membrane complex for triggering rhoptry exocytosis and invasion in Toxoplasma. Embo J [13.8]al. doi: 10.15252/embj.2022111158
Swale, C., Bellini, V., Bowler, M.W., Flore, N., Brenier-Pinchart, M.-P., Cannella, D., Belmudes, L., Mas, C., Couté, Y., Laurent, F., Scherf, A., Bougdour, A., Hakimi, M.-A., (2022). Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase. Sci Transl Med [19.3] 14, eabn3231. doi: 10.1126/scitranslmed.abn3231
Tajeri, S., Momeux, L., Saintpierre, B., Mfarrej, S., Chapple, A., Mourier, T., Shiels, B., Ariey, F., Pain, A., Langsley, G., (2022). Theileria annulata histone deacetylase 1 (TaHDAC1) initiates schizont to merozoite stage conversion. Sci Rep [5.0] 12, 12710. doi: 10.1038/s41598-022-15518-7
ten Hoeve, A.L., Braun, L., Rodriguez, M.E., Olivera, G.C., Bougdour, A., Belmudes, L., Couté, Y., Saeij, J.P.J., Hakimi, M.-A., Barragan, A., (2022). The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages. Cell Host Microbe [31.3] S1931312822005121. doi: 10.1016/j.chom.2022.10.001
Trindade, S., De Niz, M., Costa-Sequeira, M., Bizarra-Rebelo, T., Bento, F., Dejung, M., Narciso, M.V., López-Escobar, L., Ferreira, J., Butter, F., Bringaud, F., Gjini, E., Figueiredo, L.M., (2022). Slow growing behavior in African trypanosomes during adipose tissue colonization. Nat Commun [17.7] 13, 7548. doi: 10.1038/s41467-022-34622-w
Trometer, N., Roignant, M., Davioud-Charvet, E., (2022). Efficient Multigram-Scale Synthesis of 7-Substituted 3-Methyltetral-1-ones and 6-Fluoromenadione. Org Process Res Dev [3.3]. doi: 10.1021/acs.oprd.1c00421
Vigetti, L., Labouré, T., Roumégous, C., Cannella, D., Touquet, B., Mayer, C., Couté, Y., Frénal, K., Tardieux, I., Renesto, P., (2022). The BCC7 Protein Contributes to the Toxoplasma Basal Pole by Interfacing between the MyoC Motor and the IMC Membrane Network. Int J Mol Sci [5.9] 23, 5995. doi: 10.3390/ijms23115995
Wagner, M.P., Formaglio, P., Gorgette, O., Dziekan, J.M., Huon, C., Berneburg, I., Rahlfs, S., Barale, J.-C., Feinstein, S.I., Fisher, A.B., Ménard, D., Bozdech, Z., Amino, R., Touqui, L., Chitnis, C.E., (2022). Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target. Cell Rep [9.4] 39, 110923. doi: 10.1016/j.celrep.2022.110923
Walsh, D., Katris, N.J., Sheiner, L., Botté, C.Y., (2022). Toxoplasma metabolic flexibility in different growth conditions. Trends Parasitol [9.0]. doi: 10.1016/j.pt.2022.06.001
White, M., Chitnis, C.E., (2022). Potential role of vaccines in elimination of Plasmodium vivax. Parasitol Int [2.3] 102592. doi: 10.1016/j.parint.2022.102592
Allmann, S., Wargnies, M., Plazolles, N., Cahoreau, E., Biran, M., Morand, P., Pineda, E., Kulyk, H., Asencio, C., Villafraz, O., Rivière, L., Tetaud, E., Rotureau, B., Mourier, A., Portais, J.-C., Bringaud, F., (2021). Glycerol suppresses glucose consumption in trypanosomes through metabolic contest. PLoS Biol [8.0] 19, e3001359. doi: 10.1371/journal.pbio.3001359
Amrane, D., Arnold, C.-S., Hutter, S., Sanz-Serrano, J., Collia, M., Azqueta, A., Paloque, L., Cohen, A., Amanzougaghene, N., Tajeri, S., Franetich, J.-F., Mazier, D., Benoit-Vical, F., Verhaeghe, P., Azas, N., Vanelle, P., Botté, C., Primas, N., (2021a). 2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of Plasmodium falciparum. Pharmaceuticals [5.9] 14, 724. doi: 10.3390/ph14080724
Amrane, D., Primas, N., Arnold, C.-S., Hutter, S., Louis, B., Sanz-Serrano, J., Azqueta, A., Amanzougaghene, N., Tajeri, S., Mazier, D., Verhaeghe, P., Azas, N., Botté, C., Vanelle, P., (2021b). Antiplasmodial 2-thiophenoxy-3-trichloromethyl quinoxalines target the apicoplast of Plasmodium falciparum. Eur J Med Chem [6.5] 224, 113722. doi: 10.1016/j.ejmech.2021.113722
Aquilini, E., Cova, M.M., Mageswaran, S.K., Dos Santos Pacheco, N., Sparvoli, D., Penarete-Vargas, D.M., Najm, R., Graindorge, A., Suarez, C., Maynadier, M., Berry-Sterkers, L., Urbach, S., Fahy, P.R., Guérin, A.N., Striepen, B., Dubremetz, J.-F., Chang, Y.-W., Turkewitz, A.P., Lebrun, M., (2021). An Alveolata secretory machinery adapted to parasite host cell invasion. Nat Microbiol [17.7] 6, 425–434. doi: 10.1038/s41564-020-00854-z
Asad, M., Yamaryo-Botté, Y., Hossain, M.E., Thakur, V., Jain, S., Datta, G., Botté, C.Y., Mohmmed, A., (2021). An essential vesicular-trafficking phospholipase mediates neutral lipid synthesis and contributes to hemozoin formation in Plasmodium falciparum. BMC Biol [7.4] 19, 159. doi: 10.1186/s12915-021-01042-z
Baillou, A., Kasal-Hoc, N., Barc, C., Cognié, J., Pinard, A., Pezant, J., Schulthess, J., Peltier-Pain, P., Lacroix-Lamandé, S., Laurent, F., (2021). Establishment of a Newborn Lamb Gut-Loop Model to Evaluate New Methods of Enteric Disease Control and Reduce Experimental Animal Use. Vet Sci [2.3] 8, 170. doi: 10.3390/vetsci8090170
Bansal, P., Antil, N., Kumar, M., Yamaryo-Botté, Y., Rawat, R.S., Pinto, S., Datta, K.K., Katris, N.J., Botté, C.Y., Prasad, T.S.K., Sharma, P., (2021). Protein kinase TgCDPK7 regulates vesicular trafficking and phospholipid synthesis in Toxoplasma gondii. PLoS Pathog [6.8] 17, e1009325. doi: 10.1371/journal.ppat.1009325
Beaumont, M., Blanc, F., Cherbuy, C., Egidy, G., Giuffra, E., Lacroix-Lamandé, S., Wiedemann, A., (2021). Intestinal organoids in farm animals. Vet Res [3.7] 52, 33. doi: 10.1186/s13567-021-00909-x
Bringaud, F., Plazolles, N., Pineda, E., Asencio, C., Villafraz, O., Millerioux, Y., Rivière, L., Tetaud, E., (2021). Glycerol, a possible new player in the biology of trypanosomes. PLOS Pathogens 17, e1010035. doi: 10.1371/journal.ppat.1010035
Briquet, S., Gissot, M., Silvie, O., (2021a). A toolbox for conditional control of gene expression in apicomplexan parasites. Mol Microbiol [3.5] n/a. doi: 10.1111/mmi.14821
Briquet, S., Marinach, C., Silvie, O., Vaquero, C., (2021b). Preparing for Transmission: Gene Regulation in Plasmodium Sporozoites. Front Cell Infect Microbiol [5.3] 10, 907. doi: 10.3389/fcimb.2020.618430
Broster Reix, C.E., Florimond, C., Cayrel, A., Mailhé, A., Agnero-Rigot, C., Landrein, N., Dacheux, D., Havlicek, K., Bonhivers, M., Morriswood, B., Robinson, D.R., (2021). Bhalin, an Essential Cytoskeleton-Associated Protein of Trypanosoma brucei Linking TbBILBO1 of the Flagellar Pocket Collar with the Hook Complex. Microorganisms [4.2] 9, 2334. doi: 10.3390/microorganisms9112334
Broster-Reix, C.E.B., Ramanantsalama, M.R., Primo, C.D., Minder, L., Bonhivers, M., Dacheux, D., Robinson, D.R., (2021). Intrabody-Induced Cell Death by Targeting the T. brucei Cytoskeletal Protein TbBILBO1. Microbiol Spectr [7.2]. doi: 10.1128/Spectrum.00915-21
Cebrian, I., Dinamarca, S., Croce, C., Salvioni, A., Garrido, F., Fidalgo, S.E., Mayorga, L., Blanchard, N., (2021). SNX17 regulates antigen internalization and phagosomal maturation by dendritic cells. Research Square [preprint]. doi: 10.21203/rs.3.rs-144634/v1
Chantal, I., Minet, C., Berthier, D., (2021). In vitro cultivation of Trypanosoma congolense bloodstream forms: State of the art and advances. Vet Parasitol [2.7] 299, 109567. doi: 10.1016/j.vetpar.2021.109567
Cichocki, B.A., Donzel, M., Heimsch, K.C., Lesanavičius, M., Feng, L., Montagut, E.J., Becker, K., Aliverti, A., Elhabiri, M., Čėnas, N., Davioud-Charvet, E., (2021a). Plasmodium falciparum Ferredoxin-NADP+ Reductase-Catalyzed Redox Cycling of Plasmodione Generates Both Predicted Key Drug Metabolites: Implication for Antimalarial Drug Development. ACS Infect Dis [5.1] 7, 1996–2012. doi: 10.1021/acsinfecdis.1c00054
Cichocki, B.A., Khobragade, V., Donzel, M., Cotos, L., Blandin, S., Schaeffer-Reiss, C., Cianférani, S., Strub, J.-M., Elhabiri, M., Davioud-Charvet, E., (2021b). A Class of Valuable (Pro-)Activity-Based Protein Profiling Probes: Application to the Redox-Active Antiplasmodial Agent, Plasmodione. JACS Au [no IF] 1, 669–689. doi: 10.1021/jacsau.1c00025
Corrales, R.M., Vaselek, S., Neish, R., Berry, L., Brunet, C.D., Crobu, L., Kuk, N., Mateos-Langerak, J., Robinson, D.R., Volf, P., Mottram, J.C., Sterkers, Y., Bastien, P., (2021). The kinesin of the flagellum attachment zone in Leishmania is required for cell morphogenesis, cell division and virulence in the mammalian host. PLoS Pathog [6.8] 17, e1009666. doi: 10.1371/journal.ppat.1009666
Dard, C., Swale, C., Brenier-Pinchart, M.-P., Farhat, D.C., Bellini, V., Robert, M.G., Cannella, D., Pelloux, H., Tardieux, I., Hakimi, M.-A., (2021). A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection. BMC Biol [7.4] 19, 25. doi: 10.1186/s12915-021-00959-9
Dass, S., Shunmugam, S., Berry, L., Arnold, C.-S., Katris, N.J., Duley, S., Pierrel, F., Cesbron-Delauw, M.-F., Yamaryo-Botté, Y., Botté, C.Y., (2021). Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage. Nat Commun [14.9] 12, 2813. doi: 10.1038/s41467-021-22956-w
Demarta-Gatsi, C., Mécheri, S., (2021). Vector saliva controlled inflammatory response of the host may represent the Achilles heel during pathogen transmission. J Venom Anim Toxins Incl Trop Dis [2.8] 27, e20200155. doi: 10.1590/1678-9199-jvatitd-2020-0155
Donzel, M., Elhabiri, M., Davioud-Charvet, E., (2021a). Bioinspired Photoredox Benzylation of Quinones. J Org Chem [4.4] 86, 10055–10066. doi: 10.1021/acs.joc.1c00814
Donzel, M., Karabiyikli, D., Cotos, L., Elhabiri, M., Davioud-Charvet, E., (2021b). Recent Advances in Direct C-H Radical Alkylation of 1,4-Quinones. Eur J Org Chem [3.0] 2021, 3622–3633. doi: https://doi.org/10.1002/ejoc.202100452
Farhat, D.C., Bowler, M.W., Communie, G., Pontier, D., Belmudes, L., Mas, C., Corrao, C., Couté, Y., Bougdour, A., Lagrange, T., Hakimi, M., Swale, C., (2021). A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma. eLife [8.1] 10, e68312. doi: 10.7554/eLife.68312
Farhat, D.C., Hakimi, M.-A., (2021). The developmental trajectories of Toxoplasma stem from an elaborate epigenetic rewiring. Trends Parasitol [9.0]. doi: 10.1016/j.pt.2021.07.016
Feufack-Donfack, L.B., Sarah-Matio, E.M., Abate, L.M., Bouopda Tuedom, A.G., Ngano Bayibéki, A., Maffo Ngou, C., Toto, J.-C., Sandeu, M.M., Eboumbou Moukoko, C.E., Ayong, L., Awono-Ambene, P., Morlais, I., Nsango, S.E., (2021). Epidemiological and entomological studies of malaria transmission in Tibati, Adamawa region of Cameroon 6 years following the introduction of long-lasting insecticide nets. Parasites Vectors [3.9] 14, 247. doi: 10.1186/s13071-021-04745-y
Freitas, F.S.N., Njiokou, F., Ngoune, J.M.T., Sempere, G., Berthier, D., Geiger, A., (2021). Modulation of trypanosome establishment in Glossina palpalis palpalis by its microbiome in the Campo sleeping sickness focus, Cameroon. Infect Genet Evol [3.3] 90, 104763. doi: 10.1016/j.meegid.2021.104763
Gaboriaud, P., Sadrin, G., Guitton, E., Fort, G., Niepceron, A., Lallier, N., Rossignol, C., Larcher, T., Sausset, A., Guabiraba, R., Silvestre, A., Lacroix-Lamandé, S., Schouler, C., Laurent, F., Bussière, F.I., (2021). The Absence of Gut Microbiota Alters the Development of the Apicomplexan Parasite Eimeria tenella. Front Cell Infect Microbiol [5.3] 10, 632556. doi: 10.3389/fcimb.2020.632556
Gamain, B., Chêne, A., Viebig, N.K., Tuikue Ndam, N., Nielsen, M.A., (2021). Progress and Insights Toward an Effective Placental Malaria Vaccine. Front Immunol [7.6] 12, 65. doi: 10.3389/fimmu.2021.634508
Gibbins, M.P., Müller, K., Matuschewski, K., Silvie, O., Hafalla, J.C.R., (2021). Inferior T cell immunogenicity of a Plasmodium berghei model liver stage antigen expressed throughout pre-erythrocytic maturation. Parasite Immunol [2.3] e12877. doi: 10.1111/pim.12877
Guillen, N. (Ed.), (2021). Eukaryome Impact on Human Intestine Homeostasis and Mucosal Immunology: Overview of the First Eukaryome Congress at Institut Pasteur. Paris, October 16–18, 2019. Springer International Publishing. doi: 10.1007/978-3-030-44826-4
Hamada, S., Pionneau, C., Parizot, C., Silvie, O., Chardonnet, S., Marinach, C., (2021). In-depth proteomic analysis of Plasmodium berghei sporozoites using trapped ion mobility spectrometry with parallel accumulation-serial fragmentation. Proteomics [4.0] 21, 2000305. doi: 10.1002/pmic.202000305
Hammam, E., Miled, S., Bonhomme, F., Arcangioli, B., Arimondo, P.B., Scherf, A., (2021a). Variable oxygen environments and DNMT2 determine the DNA cytosine epigenetic landscape of Plasmodium falciparum. bioRxiv [preprint]. doi: 10.1101/2021.12.09.471905
Hammam, E., Sinha, A., Baumgarten, S., Nardella, F., Liang, J., Miled, S., Bonhomme, F., Erdmann, D., Arcangioli, B., Arimondo, P.B., Dedon, P., Preiser, P., Scherf, A., (2021b). Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation. mBio [7.9] e02558-21. doi: 10.1128/mBio.02558-21
Isch, C., Majneri, P., Landrein, N., Pivovarova, Y., Lesigang, J., Lauruol, F., Robinson, D.R., Dong, G., Bonhivers, M., (2021). Structural and functional studies of the first tripartite protein complex at the Trypanosoma brucei flagellar pocket collar. PLoS Pathog [6.8] 17, e1009329. doi: 10.1371/journal.ppat.1009329
Lasonder, E., More, K., Singh, S., Haidar, M., Bertinetti, D., Kennedy, E.J., Herberg, F.W., Holder, A.A., Langsley, G., Chitnis, C.E., (2021). cAMP-Dependent Signaling Pathways as Potential Targets for Inhibition of Plasmodium falciparum Blood Stages. Front Microbiol [5.6] 12, 1312. doi: 10.3389/fmicb.2021.684005
Leleu, I., Genete, D., Desnoulez, S.S., Saidi, N., Brodin, P., Lafont, F., Tomavo, S., Pied, S., (2021). A noncanonical autophagy is involved in the transfer of Plasmodium-microvesicles to astrocytes. Autophagy [16.0] 0, 1–16. doi: 10.1080/15548627.2021.1993704
Luiza-Batista, C., Nardella, F., Thiberge, S., Serra-Hassoun, M., Ferreira, M.U., Scherf, A., Garcia, S., (2021). Flowcytometric and ImageStream RNA-FISH gene expression, quantification and phenotypic characterization of blood and liver stages from human malaria species. J Infect Dis [5.2]. doi: 10.1093/infdis/jiab431
Mairet-Khedim, M., Nsango, S., Ngou, C., Menard, S., Roesch, C., Khim, N., Srun, S., Iriart, X., Lanot, T., Otam, L., Abega, F., Ayong, L., Morlais, I., Gandia, P., Witkowski, B., Berry, A., (2021). Efficacy of dihydroartemisinin/piperaquine in patients with non-complicated Plasmodium falciparum malaria in Yaoundé, Cameroon. J Antimicrob Chemother [5.8]. doi: 10.1093/jac/dkab281
Martin-Benlloch, X., Lanfranchi, D.A., Haid, S., Pietschmann, T., Davioud-Charvet, E., Elhabiri, M., (2021). Magnesium Complexes of Ladanein: A Beneficial Strategy for Stabilizing Polyphenolic Antivirals. Eur J Inorg Chem [2.5] 2021, 2764–2772. doi: 10.1002/ejic.202100341
Maurya, R., Tripathi, A., Kumar, M., Antil, N., Yamaryo‐Botté, Y., Kumar, P., Bansal, P., Doerig, C., Botté, C.Y., Prasad, T.S.K., Sharma, P., (2021). PI4‐kinase and PfCDPK7 signaling regulate phospholipid biosynthesis in Plasmodium falciparum. EMBO Rep [8.8]. doi: 10.15252/embr.202154022
Menichelli, C., Guitard, V., Martins, R.M., Lèbre, S., Lopez-Rubio, J.-J., Lecellier, C.-H., Bréhélin, L., (2021). Identification of long regulatory elements in the genome of Plasmodium falciparum and other eukaryotes. Plos Comput Biol [4.5] 17, e1008909. doi: 10.1371/journal.pcbi.1008909
Mesén-Ramírez, P., Bergmann, B., Elhabiri, M., Zhu, L., von Thien, H., Castro-Peña, C., Gilberger, T.-W., Davioud-Charvet, E., Bozdech, Z., Bachmann, A., Spielmann, T., (2021). The parasitophorous vacuole nutrient channel is critical for drug access in malaria parasites and modulates the artemisinin resistance fitness cost. Cell Host Microbe [21.0]. doi: 10.1016/j.chom.2021.11.002
Michels, P.A.M., Villafraz, O., Pineda, E., Alencar, M.B., Cáceres, A.J., Silber, A.M., Bringaud, F., (2021). Carbohydrate metabolism in Trypanosomatids: new insights revealing novel complexity, diversity and species-unique features. Exp Parasitol [2.0] 224, 108102. doi: 10.1016/j.exppara.2021.108102
Müller, K., Gibbins, M.P., Roberts, M., Reyes-Sandoval, A., Hill, A.V.S., Draper, S.J., Matuschewski, K., Silvie, O., Hafalla, J.C.R., (2021). Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination. EMBO Mol Med [12.1] 13, e13390. doi: 10.15252/emmm.202013390
Pamukcu, S., Cerutti, A., Bordat, Y., Hem, S., Rofidal, V., Besteiro, S., (2021). Differential contribution of two organelles of endosymbiotic origin to iron-sulfur cluster synthesis and overall fitness in Toxoplasma. PLoS Pathog [6.8] 17, e1010096. doi: 10.1371/journal.ppat.1010096
Pissarra, J., Pagniez, J., Petitdidier, E., Séveno, M., Vigy, O., Bras-Gonçalves, R., Lemesre, J.-L., Holzmuller, P., (2021). Proteomic Analysis of the Promastigote Secretome of Seven Leishmania Species. J Proteome Res [4.5]. doi: 10.1021/acs.jproteome.1c00244
Poncet, A.F., Bosteels, V., Hoffmann, E., Chehade, S., Rennen, S., Huot, L., Peucelle, V., Maréchal, S., Khalife, J., Blanchard, N., Janssens, S., Marion, S., (2021). The UPR sensor IRE1α promotes dendritic cell responses to control Toxoplasma gondii infection. EMBO Rep [8.8] 22, e49617. doi: 10.15252/embr.201949617
Ribeiro E Silva, A., Sausset, A., Bussière, F.I., Laurent, F., Lacroix-Lamandé, S., Silvestre, A., (2021). Genome-Wide Expression Patterns of Rhoptry Kinases during the Eimeria tenella Life-Cycle. Microorganisms [4.1] 9, 1621. doi: 10.3390/microorganisms9081621
Riloha Rivas, M., Warsame, M., Mbá Andeme, R., Nsue Esidang, S., Ncogo, P.R., Phiri, W.P., Oki Eburi, C., Edú Maye, C.E., Menard, D., Legrand, E., Berzosa, P., Garcia, L., Lao Seoane, A.K., Ntabangana, S.C., Ringwald, P., (2021). Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine and polymorphism in Plasmodium falciparum kelch13-propeller gene in Equatorial Guinea. Malar J [3.0] 20, 275. doi: 10.1186/s12936-021-03807-x
Saidi, A., Gaboriaud, P., Lalmanach, A.-C., Vanderlynden, L., Fessard, A., Vettori, P., Fort, G., Guabiraba, R., Schouler, C., Laurent, F., Guitton, E., Lecaille, F., Bussière, F.I., Lalmanach, G., (2021). Upregulation of gut cathepsin L during Eimeria tenella infection. Res Vet Sci [2.5] 140, 109–116. doi: 10.1016/j.rvsc.2021.08.013
Sinha, A., Baumgarten, S., Distiller, A., McHugh, E., Chen, P., Singh, M., Bryant, J.M., Liang, J., Cecere, G., Dedon, P.C., Preiser, P.R., Ralph, S.A., Scherf, A., (2021). Functional Characterization of the m6A-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite. mBio [7.9] 12, e00661-21. doi: 10.1128/mBio.00661-21
Souza, R.O.O., Damasceno, F.S., Marsiccobetre, S., Biran, M., Murata, G., Curi, R., Bringaud, F., Silber, A.M., (2021). Fatty acid oxidation participates in resistance to nutrient-depleted environments in the insect stages of Trypanosoma cruzi. PLoS Pathog [6.8] 17, e1009495. doi: 10.1371/journal.ppat.1009495
Sparvoli, D., Lebrun, M., (2021). Unraveling the Elusive Rhoptry Exocytic Mechanism of Apicomplexa. Trends Parasitol [9.0] 37, 622–637. doi: 10.1016/j.pt.2021.04.011
Stepinac, E., Landrein, N., Skwarzyńska, D., Wójcik, P., Lesigang, J., Lučić, I., He, C.Y., Bonhivers, M., Robinson, D.R., Dong, G., (2021). Structural studies of the shortest extended synaptotagmin with only two C2 domains from Trypanosoma brucei. iScience [5.5] 24, 102422. doi: 10.1016/j.isci.2021.102422
Tajeri, S., Haidar, M., Sakura, T., Langsley, G., (2021). Interaction between transforming Theileria parasites and their host bovine leukocytes. Mol Microbiol [3.5] 115, 860–869. doi: 10.1111/mmi.14642
Tajeri, S., Langsley, G., (2021). Theileria secretes proteins to subvert its host leukocyte. Biol Cell [4.5] 113, 220–233. doi: https://doi.org/10.1111/boc.202000096
Tounkara, M., Boulange, A., Bringaud, F., Thonnus, M., Belem, A.M.G., Bengaly, Z., Thévenon, S., Berthier, D., Rivière, L., (2021). Les méthodes de diagnostic des trypanosomiases animales africaines : avantages, limites et nouvelles pistes d’amélioration. Bulletin de l’Association des Anciens Elèves de l’Institut Pasteur 63, 31–38.
Tounkara, Magamba, Boulangé, A., Thonnus, M., Bringaud, F., Bélem, A.M.G., Bengaly, Z., Thévenon, S., Berthier, D., Rivière, L., (2021). Novel protein candidates for serodiagnosis of African animal trypanosomosis: Evaluation of the diagnostic potential of lysophospholipase and glycerol kinase from Trypanosoma brucei. PLoS Negl Trop Dis [4.4] 15, e0009985. doi: 10.1371/journal.pntd.0009985
Vela, A., Coral-Almeida, M., Sereno, D., Costales, J.A., Barnabé, C., Brenière, S.F., (2021). In vitro susceptibility of Trypanosoma cruzi discrete typing units (DTUs) to benznidazole: A systematic review and meta-analysis. PLoS Negl Trop Dis [4.4] 15, e0009269. doi: 10.1371/journal.pntd.0009269
Villafraz, O., Baudouin, H., Mazet, M., Kulyk, H., Dupuy, J.-W., Pineda, E., Botté, C., Inaoka, D.K., Portais, J.-C., Bringaud, F., (2021a). The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place. mBio [6.8] 12, e00375-21. doi: 10.1128/mBio.00375-21
Villafraz, O., Biran, M., Pineda, E., Plazolles, N., Cahoreau, E., Souza, R.O.O., Thonnus, M., Allmann, S., Tetaud, E., Rivière, L., Silber, A.M., Barrett, M.P., Zíková, A., Boshart, M., Portais, J.-C., Bringaud, F., (2021b). Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline. PLoS Pathog [6.8] 17, e1009204. doi: 10.1371/journal.ppat.1009204
Walrad, P.B., Field, M.C., Navarro, M., Robinson, D.R., (2021). Kinetoplastid cell biology and genetics, from the 2020 British Society for Parasitology Trypanosomiasis and Leishmaniasis symposium, Granada, Spain. Parasitology [3.2] 148, 1119–1124. doi: 10.1017/S0031182021000998
Wargnies, M., Plazolles, N., Schenk, R., Villafraz, O., Dupuy, J.-W., Biran, M., Bachmaier, S., Baudouin, H., Clayton, C., Boshart, M., Bringaud, F., (2021). Metabolic selection of a homologous recombination mediated gene loss protects Trypanosoma brucei from ROS production by glycosomal fumarate reductase *. J Biol Chem [5.2] 296, 100548. doi: 10.1016/j.jbc.2021.100548
Amiar, S., N. J. Katris, L. Berry, S. Dass, S. Duley, C. S. Arnold, M. J. Shears, C. Brunet, B. Touquet, G. I. McFadden, Y. Yamaryo-Botte and C. Y. Botte (2020). "Division and Adaptation to Host Environment of Apicomplexan Parasites Depend on Apicoplast Lipid Metabolic Plasticity and Host Organelle Remodeling." Cell Rep [8.1] 30(11): 3778-3792 e3779. doi: 10.1016/j.celrep.2020.02.072
Arias, M. H., M. Quiliano, S. Bourgeade-Delmas, I. Fabing, I. Chantal, D. Berthier, C. Minet, V. Eparvier, J. Sorres, D. Stien, S. Galiano, I. Aldana, A. Valentin, G. Garavito and E. Deharo (2020). "Alsinol, an arylamino alcohol derivative active against Plasmodium, Babesia, Trypanosoma, and Leishmania: past and new outcomes." Parasitol Res [1.6]. doi: doi.org/10.1007/s00436-020-06832-y
Barcons-Simon, A., C. Cordon-Obras, J. Guizetti, J. M. Bryant and A. Scherf (2020). "CRISPR Interference of a Clonally Variant GC-Rich Noncoding RNA Family Leads to General Repression of var Genes in Plasmodium falciparum." mBio [6.8] 11(1): e03054-03019. doi: doi.org/10.1128/mBio.03054-19
Bellini, V., C. Swale, M.-P. Brenier-Pinchart, T. Pezier, S. Georgeault, F. Laurent, M.-A. Hakimi and A. Bougdour (2020). "Target identification of an antimalarial oxaborole identifies AN13762 as an alternative chemotype for targeting CPSF3 in apicomplexan parasites." iScience [4.4] 0(0). doi: doi.org/10.1016/j.isci.2020.101871
Boothroyd, J. C. and M.-A. Hakimi (2020). Chapter 17 - Effectors produced by rhoptries and dense granules: an intense conversation between parasite and host in many languages. Toxoplasma gondii (Third Edition) [Book]. L. M. Weiss and K. Kim, Academic Press: 789-806. doi: doi.org/10.1016/B978-0-12-815041-2.00017-7
Bryant, J. M., S. Baumgarten, F. Dingli, D. Loew, A. Sinha, A. Claës, P. R. Preiser, P. C. Dedon and A. Scherf (2020). "Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite." Mol Syst Biol [9.0] 16(8): e9569. doi: doi.org/10.15252/msb.20209569
Cabantous, S., B. Poudiougou, A. Bergon, A. Barry, A. A. Oumar, A. M. Traore, C. Chevillard, O. Doumbo, A. Dessein and S. Marquet (2020). "Understanding Human Cerebral Malaria through a Blood Transcriptomic Signature: Evidences for Erythrocyte Alteration, Immune/Inflammatory Dysregulation, and Brain Dysfunction." Mediat Inflamm [3.8] 2020: 1-15. doi: doi.org/10.1155/2020/3280689
Cerutti, A., N. Blanchard and S. Besteiro (2020). "The Bradyzoite: A Key Developmental Stage for the Persistence and Pathogenesis of Toxoplasmosis." Pathogens [3.0] 9(3): 234. doi: doi.org/10.3390/pathogens9030234
Cordon-Obras, C., A. Barcons-Simon, C. Scheidig-Benatar, A. Claes, V. Sabatet, D. Loew and A. Scherf (2020). "An exon DNA element modulates heterochromatin spreading in the master regulator for sexual commitment in malaria parasites." bioRxiv [preprint]. doi: doi.org/10.1101/2020.06.26.163105
Dembélé, L., Franetich, J.-F., Soulard, V., Amanzougaghene, N., Tajeri, S., Bousema, T., van Gemert, G.-J., Le Grand, R., Dereuddre-Bosquet, N., Baird, J. K., Mazier, D., & Snounou, G. (2020). "Chloroquine Potentiates Primaquine Activity against Active and Latent Hepatic Plasmodia Ex Vivo: Potentials and Pitfalls" Antimicrobial Agents and Chemotherapy. 65(1), e01416-20. doi: doi.org/10.1128/AAC.01416-20
Farhat, D. C., C. Swale, C. Dard, D. Cannella, P. Ortet, M. Barakat, F. Sindikubwabo, L. Belmudes, P. J. De Bock, Y. Coute, A. Bougdour and M. A. Hakimi (2020). "A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment." Nat Microbiol [15.5] 5(4): 570-583. doi: doi.org/10.1038/s41564-020-0674-4
Feng, L., S. Pomel, P. Latre de Late, A. Taravaud, P. M. Loiseau, L. Maes, F. Cho-Ngwa, C. A. Bulman, C. Fischer, J. A. Sakanari, P. D. Ziniel, D. L. Williams and E. Davioud-Charvet (2020). "Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections." Molecules [3.3] 25(21): 5075. doi: doi.org/10.3390/molecules25215075
Fernandes, P., S. Briquet, D. Patarot, M. Loubens, B. Hoareau-Coudert and O. Silvie (2020). "The dimerisable Cre recombinase allows conditional genome editing in the mosquito stages of Plasmodium berghei." PLoS One [2.7] 15(10): e0236616. doi: doi.org/10.1371/journal.pone.0236616
Flammersfeld, A., Panyot, A., Yamaryo‐Botté, Y., Aurass, P., Przyborski, J. M., Flieger, A., Botté, C., & Pradel, G. (2020). A patatin-like phospholipase functions during gametocyte induction in the malaria parasite Plasmodium falciparum. Cell Microbiol [4.4] 22(3), e13146. doi:doi.org/10.1111/cmi.13146
Gazanion, E., L. Lacroix, P. Alberti, P. Gurung, S. Wein, M. Cheng, J. L. Mergny, A. R. Gomes and J. J. Lopez-Rubio (2020). "Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites." PLoS Genet [5.2] 16(7): e1008917. doi: doi.org/10.1371/journal.pgen.1008917
Gibbins, M. P., K. Muller, M. Glover, J. Liu, E. D. Putrianti, K. Bauza, A. Reyes-Sandoval, K. Matuschewski, O. Silvie and J. C. R. Hafalla (2020). "The importance of the immunodominant CD8+ T cell epitope of Plasmodium berghei circumsporozoite protein in parasite- and vaccine-induced protection." Infect Immun [3.2]. doi: doi.org/10.1128/IAI.00383-20
Grand, M., M. Waqasi, C. Demarta-Gatsi, Y. Wei, R. Peronet, P.-H. Commere, A. Puig, J. Axelrod, R. Caldelari, V. Heussler, R. Amino and S. Mecheri (2020). "Hepatic Inflammation Confers Protective Immunity Against Liver Stages of Malaria Parasite." Front Immunol [5.1] 11. doi: doi.org/10.3389/fimmu.2020.585502
Green, J.L., Wu, Y., Encheva, V., Lasonder, E., Prommaban, A., Kunzelmann, S., Christodoulou, E., Grainger, M., Truongvan, N., Bothe, S., Sharma, V., Song, W., Pinzuti, I., Uthaipibull, C., Srichairatanakool, S., Birault, V., Langsley, G., Schindelin, H., Stieglitz, B., Snijders, A.P., Holder, A.A., (2020). "Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development." PLoS Pathog [6.2]16(6), e1008640. doi: doi.org/10.1371/journal.ppat.1008640
Guesdon, W., Pezier, T., Menard, S., Nicolosi, A., Le Vern, Y., Silvestre, A., Diana, J., Laurent, F., & Lacroix-Lamandé, S. (2020). "Cryptosporidium parvum Subverts Antimicrobial Activity of CRAMP by Reducing Its Expression in Neonatal Mice." Microorganisms [4.2] 8(11), 1635. doi: doi.org/10.3390/microorganisms8111635
Gurung, P., A. R. Gomes, R. M. Martins, S. A. Juranek, P. Alberti, D.-E. Mbang‐Benet, S. Urbach, E. Gazanion, V. Guitard, K. Paeschke and J.-J. Lopez‐Rubio (2020). "PfGBP2 is a novel G-quadruplex binding protein in Plasmodium falciparum." Cell Microbiol [4.4] : e13303. doi: doi.org/doi.org/10.1111/cmi.13303
Guyot, N., Meudal, H., Trapp, S., Iochmann, S., Silvestre, A., Jousset, G., Labas, V., Reverdiau, P., Loth, K., Hervé, V., Aucagne, V., Delmas, A. F., Rehault-Godbert, S., & Landon, C. (2020). Structure, function, and evolution of Gga -AvBD11, the archetype of the structural avian-double-β-defensin family. PNAS [9.4], 117(1), 337–345. doi: doi.org/10.1073/pnas.1912941117
Hamada, S., C. Pionneau, C. Parizot, O. Silvie, S. Chardonnet and C. Marinach (2020). "In-depth proteomic analysis of Plasmodium berghei sporozoites using trapped ion mobility spectrometry with parallel accumulation-serial fragmentation." bioRxiv [preprint]: 2020.2011.2026.400192. doi: doi.org/10.1101/2020.11.26.400192
Hassan, A., M. F. Wlodarczyk, M. Benamar, E. Bassot, A. Salvioni, S. Kassem, A. Berry, A. Saoudi and N. Blanchard (2020). "A Virus Hosted in Malaria-Infected Blood Protects against T Cell-Mediated Inflammatory Diseases by Impairing DC Function in a Type I IFN-Dependent Manner." mBio [6.8] 11(2). doi: doi.org/10.1128/mBio.03394-19
Katris, N. J., Y. Yamaryo-Botte, J. Janouškovec, S. Shunmugam, C.-S. Arnold, A. S. P. Yang, A. Vardakis, R. J. Stewart, R. Sauerwein, G. I. McFadden, C. J. Tonkin, M.-F. Cesbron-Delauw, R. F. Waller and C. Y. Botte (2020). "Rapid kinetics of lipid second messengers controlled by a cGMP signalling network coordinates apical complex functions in Toxoplasma tachyzoites." bioRxiv [preprint]. doi: doi.org/10.1101/2020.06.19.160341
Keswani, T., Delcroix-Genete, D., Herbert, F., Leleu, I., Lambert, C., Draheim, M., Salome-Desnoulez, S., Saliou, J. M., Cazenave, P.-A., Silvie, O., Roland, J., & Pied, S. (2020). Plasmodium yoelii Uses a TLR3-Dependent Pathway to Achieve Mammalian Host Parasitism. J Immunol [4.9] 205(11), 3071–3082. doi: doi.org/10.4049/jimmunol.1901317
Kloehn, J., R. D. Oppenheim, G. Siddiqui, P.-J. De Bock, S. K. Dogga, Y. Coute, M.-A. Hakimi, D. J. Creek and D. Soldati-Favre (2020). "Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii." BMC biol [6.8] 18(1): 67. doi: doi.org/10.1186/s12915-020-00791-7
Laing, C., N. Blanchard and G. A. McConkey (2020). "Noradrenergic Signaling and Neuroinflammation Crosstalk Regulate Toxoplasma gondii-Induced Behavioral Changes." Trends Immunol [13.4]. doi: doi.org/10.1016/j.it.2020.doi.org/10.001
Langlois, A.-C., G. Manzoni, L. Vincensini, R. Coppée, C. Marinach, M. Guérin, T. Huby, V. Carrière, F.-L. Cosset, M. Dreux, E. Rubinstein and O. Silvie (2020). "Molecular determinants of SR-B1-dependent Plasmodium sporozoite entry into hepatocytes." Sci Rep [4.0] 10(1): 13509. doi: doi.org/10.1038/s41598-020-70468-2
Lecordier, L., S. Uzureau, G. Vanwalleghem, M. Deleu, J.-M. Crowet, P. Barry, B. Moran, P. Voorheis, A.-C. Dumitru, Y. Yamaryo, M. Dieu, P. Tebabi, B. Vanhollebeke, L. Lins, C. Y. Botté, D. Alsteens, Y. Dufrêne, D. Pérez-Morga, D. P. Nolan and E. Pays (2020). "The Trypanosoma brucei KIFC1 kinesin ensures the fast antibody clearance required for parasite infectivity." iScience [4.4]: 101476. doi: doi.org/10.1016/j.isci.2020.101476
Loubens, M., L. Vincensini, P. Fernandes, S. Briquet, C. Marinach and O. Silvie (2020). "Plasmodium sporozoites on the move: switching from cell traversal to productive invasion of hepatocytes." Mol Microbiol [3.9]. doi: doi.org/doi.org/10.1111/mmi.14645
Macleod, O. J. S., J. M. Bart, P. MacGregor, L. Peacock, N. J. Savill, S. Hester, S. Ravel, J. D. Sunter, C. Trevor, S. Rust, T. J. Vaughan, R. Minter, S. Mohammed, W. Gibson, M. C. Taylor, M. K. Higgins and M. Carrington (2020). "A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies." Nat Commun [12.1] 11(1): 1326. doi: doi.org/10.1038/s41467-020-15125-y
Mantilla-Muriel, L. E., A. Hernández, M. Rincón, d.-l.-T. Alejandra, M. Murillo-León, N. Cardona, M. F. Cesbron-Delauw, C. Mercier, J. C. Sepúlveda-Arias and J. E. Gomez-Marin (2020). "Serotyping, host genes and cytokines response in human ocular toxoplasmosis." Microb Pathog [2.9] 148: 104465. doi: doi.org/10.1016/j.micpath.2020.104465
Martinez, G., J. Beurois, D. Dacheux, C. Cazin, M. Bidart, Z. E. Kherraf, D. R. Robinson, V. Satre, G. Le Gac, C. Ka, I. Gourlaouen, Y. Fichou, G. Petre, E. Dulioust, R. Zouari, N. Thierry-Mieg, A. Toure, C. Arnoult, M. Bonhivers, P. Ray and C. Coutton (2020). "Biallelic variants in MAATS1 encoding CFAP91, a calmodulin-associated and spoke-associated complex protein, cause severe astheno-teratozoospermia and male infertility." J Med Genet [4.9]: jmedgenet-2019-106775. doi: doi.org/10.1136/jmedgenet-2019-106775
Menichelli, C., V. Guitard, R. M. Martins, S. Lebre, J.-J. Lopez-Rubio, C. H. Lecellier and L. Brehelin (2020). "Identification of long regulatory elements in the genome of Plasmodium falciparum and other eukaryotes." bioRxiv [preprint]. doi: doi.org/10.1101/2020.06.02.130468
Mochizuki, K., D. K. Inaoka, M. Mazet, T. Shiba, K. Fukuda, H. Kurasawa, Y. Millerioux, M. Boshart, E. O. Balogun, S. Harada, K. Hirayama, F. Bringaud and K. Kita (2020). "The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei." BBA - Bioenergetics [3.5] 1861(11): 148283. doi: doi.org/doi.org/10.1016/j.bbabio.2020.148283
More, K. R., I. Kaur, Q. G. Gianetto, B. M. Invergo, T. Chaze, R. Jain, C. Huon, P. Gutenbrunner, H. Weisser, M. Matondo, J. S. Choudhary, G. Langsley, S. Singh and C. E. Chitnis (2020). "Phosphorylation-Dependent Assembly of a 14-3-3 Mediated Signaling Complex during Red Blood Cell Invasion by Plasmodium falciparum Merozoites." mBio [6.8] 11(4). doi: doi.org/10.1128/mBio.01287-20
Mounkoro, P., T. Michel, M.-P. Golinelli-Cohen, S. Blandin, E. Davioud-Charvet and B. Meunier (2020). "A role for the succinate dehydrogenase in the mode of action of the redox-active antimalarial drug, plasmodione." Free Radic Biol Med [6.2]. doi: doi.org/10.1016/j.freeradbiomed.2020.11.010
Müller, K., M. P. Gibbins, A. Reyes-Sandoval, A. V. S. Hill, S. J. Draper, K. Matuschewski, O. Silvie and J. C. R. Hafalla (2020). "Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination." bioRxiv [preprint]: 2020.2009.2003.281238. doi: doi.org/10.1101/2020.09.03.281238
Neveu, G., C. Richard, F. Dupuy, P. K. Behera, F. Volpe, P. A. Subramani, B. Marcel-Zerrougui, P. Vallin, M. Andrieu, A. M. Minz, N. Azar, R. M. Martins, A. Lorthiois, F. Gazeau, J. J. Lopez-Rubio, D. Mazier, A. K. A. Silva, S. Satpathi, S. Wassmer, F. Verdier and C. Lavazec (2020). "Plasmodium falciparum sexual parasites develop in human erythroblasts and affect erythropoiesis." Blood [17.5]. doi: doi.org/10.1182/blood.2019004746
Rchiad, Z., M. Haidar, H. R. Ansari, S. Tajeri, S. Mfarrej, F. Ben Rached, A. Kaushik, G. Langsley and A. Pain (2020). "Novel tumour suppressor roles for GZMA and RASGRP1 in Theileria annulata-transformed macrophages and human B-lymphoma cells." Cell Microbiol [3.4] : e13255. doi: doi.org/10.1111/cmi.13255
Suarez, C., M. B. Lodoen and M. Lebrun (2020). Assessing Rhoptry Secretion in T. gondii. Methods Mol Biol [Book]. C. J. Tonkin. 2071: 143-155. doi: doi.org/10.1007/978-1-4939-9857-9_8
Tretina, K., M. Haidar, S. A. Madsen-Bouterse, T. Sakura, S. Mfarrej, L. Fry, M. Chaussepied, A. Pain, D. P. Knowles, V. M. Nene, D. Ginsberg, C. A. Daubenberger, R. P. Bishop, G. Langsley and J. C. Silva (2020). "Theileria parasites subvert E2F signaling to stimulate leukocyte proliferation." Sci Rep [4.0] 10(1): 3982. doi: doi.org/10.1038/s41598-020-60939-x
Venugopal, K., S. Chehade, E. Werkmeister, N. Barois, J. Periz, F. Lafont, I. Tardieux, J. Khalife, G. Langsley, M. Meissner and S. Marion (2020). "Rab11A regulates dense granule transport and secretion during Toxoplasma gondii invasion of host cells and parasite replication." PLoS Pathog [6.2] 16(5): e1008106. doi: doi.org/10.1371/journal.ppat.1008106
Villafraz, O., M. Biran, E. Pineda, N. Plazolles, E. Cahoreau, R. O. O. Souza, M. Thonnus, S. Allmann, E. Tetaud, L. Rivière, A. M. Silber, M. P. Barrett, A. Zíková, M. Boshart, J.-C. Portais and F. Bringaud (2020). "Fly stage trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in near physiological conditions." bioRxiv [preprint]: 2020.2012.2017.423221. doi: doi.org/10.1101/2020.12.17.423221
Wargnies, M., N. Plazolles, R. Schenk, O. Villafraz, J.-W. Dupuy, M. Biran, S. Bachmaier, H. Baudouin, C. Clayton, M. Boshart and F. Bringaud (2020). "Metabolic selection of a homologous recombination mediated loss of glycosomal fumarate reductase in Trypanosoma brucei." bioRxiv [preprint]: 2020.2011.2029.403048. doi: doi.org/10.1101/2020.11.29.403048
Wilson, S. K., J. Heckendorn, B. Martorelli Di Genova, L. L. Koch, P. J. Rooney, N. Morrissette, M. Lebrun and L. J. Knoll (2020). "A Toxoplasma gondii patatin-like phospholipase contributes to host cell invasion." PLoS Pathog [6.2] 16(7): e1008650. doi: doi.org/10.1371/journal.ppat.1008650
Yagoubat, A., R. M. Corrales, P. Bastien, M. F. Lévêque and Y. Sterkers (2020). "Gene Editing in Trypanosomatids: Tips and Tricks in the CRISPR-Cas9 Era." Trends Parasitol [6.9]. doi: doi.org/doi.org/10.1016/j.pt.2020.06.005
Yagoubat, A., L. Crobu, L. Berry, N. Kuk, M. Lefebvre, A. Sarrazin, P. Bastien and Y. Sterkers (2020). "Universal highly efficient conditional knockout system in Leishmania, with a focus on untranscribed region preservation." Cell Microbiol [3.4] 22(5): e13159. doi: doi.org/10.1111/cmi.13159
Allmann, S., Wargnies, M., Cahoreau, E., Biran, M., Plazolles, N., Morand, P., Pineda, E., Kulyk, H., Asencio, C., Villafraz, O., Rivière, L., Tétaud, E., Rotureau, B., Mourier, A., Portais, J.-C., Bringaud, F., (2019). “Metabolic contest”, a new way to control carbon source preference. bioRxiv [preprint] 800839. doi:10.1101/800839
Amiar, S., Katris, N.J., Berry, L., Dass, S., Shears, M.J., Brunet, C., Touquet, B., Hakimi, M.-A., McFadden, G.I., Yamaryo-Botté, Y., Botté, C.Y., (2019). Division and adaptation to host nutritional environment of apicomplexan parasites depend on apicoplast lipid metabolic plasticity and host organelles remodelling. bioRxiv [preprint]. doi:10.1101/585737
Asad, M., Yamaryo-Botté, Y., Hossain, M.E., Thakur, V., Jain, S., Datta, G., Botté, C.Y., Mohmmed, A., (2019). A lysophospholipase plays role in generation of neutral-lipids required for hemozoin formation in malaria parasite. bioRxiv [preprint]. doi:10.1101/808709
Azevedo, J., Picart, C., Dureau, L., Pontier, D., Jaquinod-Kieffer, S., Hakimi, M.A., Lagrange, T., (2019). UAP56 associates with DRM2 and is localized to chromatin in Arabidopsis. FEBS Open Bio [2.0] 9, 973–985. doi:10.1002/2211-5463.12627
Baumgarten, S., Bryant, J.M., Sinha, A., Reyser, T., Preiser, P.R., Dedon, P.C., Scherf, A., (2019). Transcriptome-wide dynamics of extensive m6A mRNA methylation during Plasmodium falciparum blood-stage development. Nat Microbiol [14.2] 4, 2246–2259. doi:10.1038/s41564-019-0521-7
Beri, D., Ramdani, G., Balan, B., Gadara, D., Poojary, M., Momeux, L., Tatu, U., Langsley, G., (2019). Insights into physiological roles of unique metabolites released from Plasmodium-infected RBCs and their potential as clinical biomarkers for malaria. Sci Rep [4.1] 9, 2875. doi:10.1038/s41598-018-37816-9
Besteiro, S., (2019). The role of host autophagy machinery in controlling Toxoplasma infection. Virulence [4.8] 10, 438–447. doi:10.1080/21505594.2018.1518102
Braun, L., Brenier-Pinchart, M.P., Hammoudi, P.M., Cannella, D., Kieffer-Jaquinod, S., Vollaire, J., Josserand, V., Touquet, B., Coute, Y., Tardieux, I., Bougdour, A., Hakimi, M.A., (2019). The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-kappaB signalling via EZH2. Nat Microbiol [14.2]. doi:10.1038/s41564-019-0431-8
Cotos, L., Donzel, M., Elhabiri, M., Davioud-Charvet, E., (2019). A Mild and Versatile Friedel-Crafts Methodology for the Diversity-Oriented Synthesis of Redox-Active 3-Benzoylmenadiones with Tuneable Redox Potentials. Chem-Eur J [5.2]. doi:10.1002/chem.201904220
Courtois, P., Nabos, P., Nzoumbou-Boko, R., Reix, C.E., Dauchy, F.-A., Daulouede, S., Bringaud, F., Robinson, D.R., Vincendeau, P., (2019). Purification of Extracellular Trypanosomes, Including African, from Blood by Anion-Exchangers (Diethylaminoethyl-cellulose Columns). JoVE [1.2] e58415. doi:doi:10.3791/58415
Dauchy, F.A., Contin-Bordes, C., Nzoumbou-Boko, R., Bonhivers, M., Landrein, N., Robinson, D.R., Rambert, J., Courtois, P., Daulouede, S., Vincendeau, P., (2019). Trypanosoma brucei gambiense excreted/secreted factors impair lipopolysaccharide-induced maturation and activation of human monocyte-derived dendritic cells. Parasite Immunol [2.8] 41, e12632. doi:10.1111/pim.12632
Deloule, V., Boisset, C., Hannani, D., Suau, A., Le Gouellec, A., Chroboczek, J., Botté, C., Yamario-Botté, Y., Chirat, C., Toussaint, B., (2019). Prebiotic role of softwood hemicellulose in healthy mice model. J Funct Foods [3.2] 103688. doi:10.1016/j.jff.2019.103688
Demarta-Gatsi, C., Rivkin, A., Di Bartolo, V., Peronet, R., Ding, S., Commere, P.-H., Guillonneau, F., Bellalou, J., Brûlé, S., Abou Karam, P., Cohen, S.R., Lagache, T., Janse, C.J., Regev-Rudzki, N., Mécheri, S., (2019). Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses. Cell Microbiol [4.4] 0, e13021. doi:10.1111/cmi.13021
Dorin-Semblat, D., Tetard, M., Claes, A., Semblat, J.P., Dechavanne, S., Fourati, Z., Hamelin, R., Armand, F., Matesic, G., Nunes-Silva, S., Srivastava, A., Gangnard, S., Lopez-Rubio, J.J., Moniatte, M., Doerig, C., Scherf, A., Gamain, B., (2019). Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA. PLoS Biol [8.4] 17, e3000308. doi:10.1371/journal.pbio.3000308
Fernandes, P.M., Kinkead, J., McNae, I.W., Bringaud, F., Michels, P.A.M., Walkinshaw, M.D., (2019). The kinetic characteristics of human and Trypanosomatid phosphofructokinases for the reverse reaction. Biochem J [3.9] 476, 179–191. doi:10.1042/BCJ20180635
Florini, F., Naguleswaran, A., Gharib, W.H., Bringaud, F., Roditi, I., (2019). Unexpected diversity in eukaryotic transcription revealed by the retrotransposon hotspot family of Trypanosoma brucei. Nucleic Acids Res [11.2] 47, 1725–1739. doi:10.1093/nar/gky1255
Fox, B.A., Guevara, R.B., Rommereim, L.M., Falla, A., Bellini, V., Petre, G., Rak, C., Cantillana, V., Dubremetz, J.F., Cesbron-Delauw, M.F., Taylor, G.A., Mercier, C., Bzik, D.J., (2019). Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Orchestrate Chronic Infection and GRA12 Underpins Resistance to Host Gamma Interferon. mBio [6.7] 10, e00589-19. doi:10.1128/mBio.00589-19
Guillen, N., (2019). The interaction between Entamoeba histolytica and enterobacteria shed light on an ancient antibacterial response. Cell Microbiol [4.4] 0, e13039. doi:10.1111/cmi.13039
Haidar, M., Metheni, M., Batteux, F., Langsley, G., (2019). TGF-beta2, catalase activity, H2O2 output and metastatic potential of diverse types of tumour. Free Radic Biol Med [6.0] 134, 282–287. doi:10.1016/j.freeradbiomed.2019.01.010
Hammam, E., Ananda, G., Sinha, A., Scheidig-Benatar, C., Bohec, M., Preiser, P.R., Dedon, P.C., Scherf, A., Vembar, S.S., (2019). Discovery of a new predominant cytosine DNA modification that is linked to gene expression in malaria parasites. Nucleic Acids Res. doi:10.1093/nar/gkz1093
Hassan, A., Wlodarczyk, M.F., Benamar, M., Bassot, E., Salvioni, A., Kassem, S., Berry, A., Saoudi, A., Blanchard, N., (2019). A virus hosted in malaria-infected blood protects against T cell-mediated inflammatory diseases by impairing DC function in a type I IFN-dependent manner. bioRxiv [preprint] 830687. doi:10.1101/830687
Hernandez-Cuevas, N.A., Jhingan, G.D., Petropolis, D., Vargas, M., Guillen, N., (2019). Acetylation is the most abundant actin modification in Entamoeba histolytica and modifications of actin’s amino-terminal domain change cytoskeleton activities. Cell Microbiol [4.4] 21, e12983. doi:10.1111/cmi.12983
Herrera‐Solorio, A.M., Vembar, S.S., MacPherson, C.R., Lozano‐Amado, D., Meza, G.R., Xoconostle‐Cazares, B., Martins, R.M., Chen, P., Vargas, M., Scherf, A., Hernández‐Rivas, R., (2019). Clipped histone H3 is integrated into nucleosomes of DNA replication genes in the human malaria parasite <em>Plasmodium falciparum</em>. EMBO reports [8.7] 20, e46331. doi:10.15252/embr.201846331
Jamonneau, V., Truc, P., Grébaut, P., Herder, S., Ravel, S., Solano, P., De Meeus, T., (2019). Trypanosoma brucei gambiense Group 2: The Unusual Suspect. Trends in Parasitology. doi:10.1016/j.pt.2019.09.002
Keswani, T., Roland, J., Herbert, F., Delcroix-Genete, D., Bauderlique-Le Roy, H., Gaayeb, L., Cazenave, P.-A., Pied, S., (2019). Expression of CD300lf by microglia contributes to resistance to cerebral malaria by impeding the neuroinflammation. Genes Immun. doi:10.1038/s41435-019-0085-9
Latre de Late, P., Haidar, M., Ansari, H., Tajeri, S., Szarka, E., Alexa, A., Woods, K., Remenyi, A., Pain, A., Langsley, G., (2019). Theileria highjacks JNK2 into a complex with the macroschizont GPI (GlycosylPhosphatidylInositol)-anchored surface protein p104. Cell Microbiol [4.4] 21, e12973. doi:10.1111/cmi.12973
Lee, M.C.S., Lindner, S.E., Lopez-Rubio, J.J., Llinas, M., (2019). Cutting back malaria: CRISPR/Cas9 genome editing of Plasmodium. Brief Funct Genomics [3.1]. doi:10.1093/bfgp/elz012
Lejon, V., Buscher, P., Nzoumbou-Boko, R., Bossard, G., Jamonneau, V., Bucheton, B., Truc, P., Lemesre, J.L., Solano, P., Vincendeau, P., (2019). The separation of trypanosomes from blood by anion exchange chromatography: From Sheila Lanham’s discovery 50 years ago to a gold standard for sleeping sickness diagnosis. PLoS Negl Trop Dis [3.8] 13, e0007051. doi:10.1371/journal.pntd.0007051
Loeuillet, C., Mondon, A., Kamche, S., Curri, V., Boutonnat, J., Cavailles, P., Cesbron-Delauw, M.F., (2019). Toxoplasma Hypervirulence in the Rat Model Parallels Human Infection and Is Modulated by the Toxo1 Locus. Front Cell Infect Microbiol [3.5] 9, 134. doi:10.3389/fcimb.2019.00134
Lorès, P., Dacheux, D., Kherraf, Z.-E., Nsota Mbango, J.-F., Coutton, C., Stouvenel, L., Ialy-Radio, C., Amiri-Yekta, A., Whitfield, M., Schmitt, A., Cazin, C., Givelet, M., Ferreux, L., Fourati Ben Mustapha, S., Halouani, L., Marrakchi, O., Daneshipour, A., El Khouri, E., Do Cruzeiro, M., Favier, M., Guillonneau, F., Chaudhry, M., Sakheli, Z., Wolf, J.-P., Patrat, C., Gacon, G., Savinov, S.N., Hosseini, S.H., Robinson, D.R., Zouari, R., Ziyyat, A., Arnoult, C., Dulioust, E., Bonhivers, M., Ray, P.F., Touré, A., (2019). Mutations in TTC29, Encoding an Evolutionarily Conserved Axonemal Protein, Result in Asthenozoospermia and Male Infertility. The American Journal of Human Genetics. doi:10.1016/j.ajhg.2019.10.007
Marozienė, A., Lesanavičius, M., Davioud-Charvet, E., Aliverti, A., Grellier, P., Šarlauskas, J., Čėnas, N., (2019). Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase. Molecules [3.1] 24, 4509. doi:10.3390/molecules24244509
Martin-Benlloch, X., Haid, S., Novodomska, A., Rominger, F., Pietschmann, T., Davioud-Charvet, E., Elhabiri, M., (2019). Physicochemical Properties Govern the Activity of Potent Antiviral Flavones. ACS Omega [2.6] 4, 4871–4887. doi:10.1021/acsomega.8b03332
Mazier, D., Paris, L., (2019). Maladies parasitaires : vous avez dit « éradiquer » ? Med Sci (Paris) 35, 723–724. doi:10.1051/medsci/2019171
Mounkoro, P., Michel, T., Blandin, S., Golinelli-Cohen, M.P., Davioud-Charvet, E., Meunier, B., (2019). Investigating the mode of action of the redox-active antimalarial drug plasmodione using the yeast model. Free Radic Biol Med [5.7] 141, 269–278. doi:10.1016/j.freeradbiomed.2019.06.026
Nardella, F., Halby, L., Hammam, E., Erdmann, D., Cadet-Daniel, V., Peronet, R., Ménard, D., Witkowski, B., Mecheri, S., Scherf, A., Arimondo, P.B., (2019). DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites. ACS Cent. Sci. doi:10.1021/acscentsci.9b00874
Rchiad, Z., Haidar, M., Ansari, H.R., Tajeri, S., Mfarrej, S., Rached, F.B., Kaushik, A., Langsley, G., Pain, A., (2019). Novel tumor suppressor roles for GZMAand RASGRP1 in dissemination of both Theileria annulatatransformed macrophages and human B-lymphoma cells. bioRxiv [preprint] 338160. doi:10.1101/338160
Salvioni, A., Belloy, M., Lebourg, A., Bassot, E., Cantaloube-Ferrieu, V., Vasseur, V., Blanié, S., Liblau, R.S., Suberbielle, E., Robey, E.A., Blanchard, N., (2019). Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons. Cell Rep [7.8] 27, 3254-3268.e8. doi:10.1016/j.celrep.2019.05.051
Semenovskaya, K., Lévêque, M.F., Berry, L., Bordat, Y., Dubremetz, J.-F., Lebrun, M., Besteiro, S., (2019). TgZFP2 is a novel zinc finger protein involved in coordinating mitosis and budding in Toxoplasma. Cell Microbiol [4.4] 0, e13120. doi:10.1111/cmi.13120
Suarez, C., Lentini, G., Ramaswamy, R., Maynadier, M., Aquilini, E., Berry-Sterkers, L., Cipriano, M., Chen, A.L., Bradley, P., Striepen, B., Boulanger, M.J., Lebrun, M., (2019). A lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites. Nat Commun [11.9] 10, 4041. doi:10.1038/s41467-019-11979-z
Swale, C., Bougdour, A., Gnahoui-David, A., Tottey, J., Georgeault, S., Laurent, F., Palencia, A., Hakimi, M.-A., (2019). Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection. Sci Transl Med [17.2] 11, eaax7161. Doi: 10.1126/scitranslmed.aax7161
Szöőr, B., Simon, D.V., Rojas, F., Young, J., Robinson, D.R., Krüger, T., Engstler, M., Matthews, K.R., (2019). Positional Dynamics and Glycosomal Recruitment of Developmental Regulators during Trypanosome Differentiation. MBio 10. doi:10.1128/mBio.00875-19
van der Laan, S., Lévêque, M., Marcellin, G., Vezenkov, L., Lannay, Y., Dubra, G., Bompard, G., Ovejero, S., Urbach, S., Burgess, A., Amblard, M., Sterkers, Y., Bastien, P., Rogowski, K., (2019). Evolutionary Divergence of Enzymatic Mechanisms for Tubulin Detyrosination. Cell Reports [7.8]. doi:10.1016/j.celrep.2019.11.074
Venugopal, K., Chehade, S., Werkmeister, E., Barois, N., Periz, J., Lafont, F., Tardieux, .I, Khalife, J., Langsley, G., Meissner, M., Marion, S. (2019). Rab11A regulates the constitutive secretory pathway during Toxoplasma gondii invasion of host cells and parasite replication. bioRxiv [preprint] 782391. doi:10.1101/782391
Vergnes, B., Gazanion, E., Mariac, C., Du Manoir, M., Sollelis, L., Lopez-Rubio, J.J., Sterkers, Y., Banuls, A.L., (2019). A single amino acid substitution (H451Y) in Leishmania calcium-dependent kinase SCAMK confers high tolerance and resistance to antimony. J Antimicrob Chemother [5.1]. doi:10.1093/jac/dkz334
Vidilaseris, K., Landrein, N., Pivovarova, Y., Lesigang, J., Aeksiri, N., Robinson, D.R., Bonhivers, M., Dong, G., (2019). Crystal structure of the TbBILBO1 N-terminal domain reveals a ubiquitin fold with a long rigid loop for the binding of its partner. bioRxiv [preprint] 738153. doi:10.1101/738153
Vidilaseris, K., Landrein, N., Pivovarova, Y., Lesigang, J., Aeksiri, N., Robinson, D.R., Bonhivers, M., Dong, G., (2019). Crystal structure of the N-terminal domain of the trypanosome flagellar protein BILBO1 reveals a ubiquitin fold with a long structured loop for protein binding. J Biol Chem [4.1] jbc.RA119.010768. doi:10.1074/jbc.RA119.010768
Abah, S.E., Burte, F., Marquet, S., Brown, B.J., Akinkunmi, F., Oyinloye, G., Afolabi, N.K., Omokhodion, S., Lagunju, I., Shokunbi, W.A., Wahlgren, M., Dessein, H., Argiro, L., Dessein, A.J., Noyvert, B., Hunt, L., Elgar, G., Sodeinde, O., Holder, A.A., Fernandez-Reyes, D., (2018). Low plasma haptoglobin is a risk factor for life-threatening childhood severe malarial anemia and not an exclusive consequence of hemolysis. Sci Rep [4.1] 8, 17527. doi:10.1038/s41598-018-35944-w
Aliprandini, E., Tavares, J., Panatieri, R.H., Thiberge, S., Yamamoto, M.M., Silvie, O., Ishino, T., Yuda, M., Dartevelle, S., Traincard, F., Boscardin, S.B., Amino, R., (2018). Cytotoxic anti-circumsporozoite antibodies target malaria sporozoites in the host skin. Nat Microbiol [14.2] 3, 1224–1233. doi:10.1038/s41564-018-0254-z
Belmonte-Reche, E., Martinez-Garcia, M., Guedin, A., Zuffo, M., Arevalo-Ruiz, M., Doria, F., Campos-Salinas, J., Maynadier, M., Lopez-Rubio, J.J., Freccero, M., Mergny, J.L., Perez-Victoria, J.M., Morales, J.C., (2018). G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents. J Med Chem [6.3] 61, 1231–1240. doi:10.1021/acs.jmedchem.7b01672
Berry, L., Chen, C.T., Francia, M.E., Guerin, A., Graindorge, A., Saliou, J.M., Grandmougin, M., Wein, S., Bechara, C., Morlon-Guyot, J., Bordat, Y., Gubbels, M.J., Lebrun, M., Dubremetz, J.F., Daher, W., (2018). Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny. Cell Mol Life Sci [6.7] 75, 4417–4443. doi:10.1007/s00018-018-2889-6
Bosson-Vanga, H., Franetich, J.F., Soulard, V., Sossau, D., Tefit, M., Kane, B., Vaillant, J.C., Borrmann, S., Muller, O., Dereuddre-Bosquet, N., Le Grand, R., Silvie, O., Mazier, D., (2018). Differential activity of methylene blue against erythrocytic and hepatic stages of Plasmodium. Malar J [2.7] 17, 143. doi:10.1186/s12936-018-2300-y
Botte, C.Y., McFadden, G.I., Yamaryo-Botte, Y., (2018). Isolating the Plasmodium falciparum Apicoplast Using Magnetic Beads. Methods Mol Biol [1.9], Plastids: Methods and Protocols 1829, 205–212.
Botte, C.Y., Yamaryo-Botte, Y., (2018). Complex Endosymbioses II: The Nonphotosynthetic Plastid of Apicomplexa Parasites (The Apicoplast) and Its Integrated Metabolism. Methods Mol Biol [1.9] 1829, 37–54. doi:10.1007/978-1-4939-8654-5_3
Bruening, J., Lasswitz, L., Banse, P., Kahl, S., Marinach, C., Vondran, F.W., Kaderali, L., Silvie, O., Pietschmann, T., Meissner, F., Gerold, G., (2018). Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB. PLoS Pathog [6.6] 14, e1007111. doi:10.1371/journal.ppat.1007111
Bryant, J.M., Baumgarten, S., Lorthiois, A., Scheidig-Benatar, C., Claes, A., Scherf, A., (2018). De Novo Genome Assembly of a Plasmodium falciparum NF54 Clone Using Single-Molecule Real-Time Sequencing. Genome Announc [no IF] 6. doi:10.1128/genomeA.01479-17
Buscher, P., Bart, J.M., Boelaert, M., Bucheton, B., Cecchi, G., Chitnis, N., Courtin, D., Figueiredo, L.M., Franco, J.R., Grebaut, P., Hasker, E., Ilboudo, H., Jamonneau, V., Koffi, M., Lejon, V., MacLeod, A., Masumu, J., Matovu, E., Mattioli, R., Noyes, H., Picado, A., Rock, K.S., Rotureau, B., Simo, G., Thevenon, S., Trindade, S., Truc, P., Van Reet, N., (2018). Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination? Trends in parasitology 34, 197–207. doi:10.1016/j.pt.2017.11.008
Chevillard, C., Nunes, J.P.S., Frade, A.F., Almeida, R.R., Pandey, R.P., Nascimento, M.S., Kalil, J., Cunha-Neto, E., (2018). Disease Tolerance and Pathogen Resistance Genes May Underlie Trypanosoma cruzi Persistence and Differential Progression to Chagas Disease Cardiomyopathy. Front Immunol [5.5] 9, 2791. doi:10.3389/fimmu.2018.02791
Claessens, A., Harris, L.M., Stanojcic, S., Chappell, L., Stanton, A., Kuk, N., Veneziano-Broccia, P., Sterkers, Y., Rayner, J.C., Merrick, C.J., (2018). RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics. PLoS Genet [6.1] 14, e1007490. doi:10.1371/journal.pgen.1007490
Coutton, C., Vargas, A.S., Amiri-Yekta, A., Kherraf, Z.E., Ben Mustapha, S.F., Le Tanno, P., Wambergue-Legrand, C., Karaouzene, T., Martinez, G., Crouzy, S., Daneshipour, A., Hosseini, S.H., Mitchell, V., Halouani, L., Marrakchi, O., Makni, M., Latrous, H., Kharouf, M., Deleuze, J.F., Boland, A., Hennebicq, S., Satre, V., Jouk, P.S., Thierry-Mieg, N., Conne, B., Dacheux, D., Landrein, N., Schmitt, A., Stouvenel, L., Lores, P., El Khouri, E., Bottari, S.P., Faure, J., Wolf, J.P., Pernet-Gallay, K., Escoffier, J., Gourabi, H., Robinson, D.R., Nef, S., Dulioust, E., Zouari, R., Bonhivers, M., Toure, A., Arnoult, C., Ray, P.F., (2018). Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human. Nat Commun [12.1] 9, 686. doi:10.1038/s41467-017-02792-7
Droll, D., Wei, G., Guo, G., Fan, Y., Baumgarten, S., Zhou, Y., Xiao, Y., Scherf, A., Zhang, Q., (2018). Disruption of the RNA exosome reveals the hidden face of the malaria parasite transcriptome. RNA Biol [5.2] 15, 1206–1214. doi:10.1080/15476286.2018.1517014
Dubois, D., Fernandes, S., Amiar, S., Dass, S., Katris, N.J., Botte, C.Y., Yamaryo-Botte, Y., (2018). Toxoplasma gondii acetyl-CoA synthetase is involved in fatty acid elongation (of long fatty acid chains) during tachyzoite life stages. J Lipid Res [4.8] 59, 994–1004. doi:10.1194/jlr.M082891
Eyssen, L.E., Vather, P., Jackson, L., Ximba, P., Biteau, N., Baltz, t., Boulange, A., Buscher, P., Coetzer, T.H.T., (2018). Recombinant and native TviCATL from Trypanosoma vivax: Enzymatic characterisation and evaluation as a diagnostic target for animal African trypanosomosis. Molecular and Biochemical Parasitology 223, 50–54. doi:10.1016/j.molbiopara.2018.07.001
Feng, L., Lanfranchi, D.A., Cotos, L., Cesar-Rodo, E., Ehrhardt, K., Goetz, A.-A., Zimmermann, H., Fenaille, F., Blandin, S.A., Davioud-Charvet, E., (2018). Synthesis of plasmodione metabolites and 13C-enriched plasmodione as chemical tools for drug metabolism investigation. Org Biomol Chem [3.6] 16, 2647–2665. doi:10.1039/C8OB00227D
Fleury, A., Alaez, C., Dessein, A., Rosetti, M., Saenz, B., Hernandez, M., Bobes, R.J., Ramirez-Aquino, R., Sciutto, E., Gorodezky, C., Fragoso, G., (2018). No association of IL2, IL4, IL6, TNF, and IFNG gene polymorphisms was found with Taenia solium human infection or neurocysticercosis severity in a family-based study. Hum Immunol [2.3] 79, 578–582. doi:10.1016/j.humimm.2018.04.011
Haidar, M., Rchiad, Z., Ansari, H.R., Ben-Rached, F., Tajeri, S., Latre de Late, P., Langsley, G., Pain, A., (2018). miR-126-5p by direct targeting of JNK-interacting protein-2 (JIP-2) plays a key role in Theileria-infected macrophage virulence. PLoS Pathog 14, e1006942. doi:10.1371/journal.ppat.1006942
He, H., Brenier-Pinchart, M.P., Braun, L., Kraut, A., Touquet, B., Coute, Y., Tardieux, I., Hakimi, M.A., Bougdour, A., (2018). Characterization of a Toxoplasma effector uncovers an alternative GSK3/beta-catenin-regulatory pathway of inflammation. eLife [7.6] 7. doi:10.7554/eLife.39887
Holzmuller, P., Geiger, A., Nzoumbou-Boko, R., Pissarra, J., Hamrouni, S., Rodrigues, V., Dauchy, F.A., Lemesre, J.L., Vincendeau, P., Bras-Goncalves, R., (2018). Trypanosomatid Infections: How Do Parasites and Their Excreted-Secreted Factors Modulate the Inducible Metabolism of l-Arginine in Macrophages? Front Immunol [6.4] 9, 778. doi:10.3389/fimmu.2018.00778
Kherraf, Z.E., Amiri-Yekta, A., Dacheux, D., Karaouzene, T., Coutton, C., Christou-Kent, M., Martinez, G., Landrein, N., Le Tanno, P., Fourati Ben Mustapha, S., Halouani, L., Marrakchi, O., Makni, M., Latrous, H., Kharouf, M., Pernet-Gallay, K., Gourabi, H., Robinson, D.R., Crouzy, S., Blum, M., Thierry-Mieg, N., Toure, A., Zouari, R., Arnoult, C., Bonhivers, M., Ray, P.F., (2018). A Homozygous Ancestral SVA-Insertion-Mediated Deletion in WDR66 Induces Multiple Morphological Abnormalities of the Sperm Flagellum and Male Infertility. Am J Hum Genet [8.9] 103, 400–412. doi:10.1016/j.ajhg.2018.07.014
Kovářová, J., Pountain, A.W., Wildridge, D., Weidt, S., Bringaud, F., Burchmore, R.J.S., Achcar, F., Barrett, M.P., (2018). Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana. PLoS Pathog [6.6] 14, e1006953. doi:10.1371/journal.ppat.1006953
Langlois, A.C., Marinach, C., Manzoni, G., Silvie, O., (2018). Plasmodium sporozoites can invade hepatocytic cells independently of the Ephrin receptor A2. PLoS One [2.8] 13, e0200032. doi:10.1371/journal.pone.0200032
Manich, M., Hernandez-Cuevas, N., Ospina-Villa, J.D., Syan, S., Marchat, L.A., Olivo-Marin, J.-C., Guillén, N., (2018). Morphodynamics of the Actin-Rich Cytoskeleton in Entamoeba histolytica. Front Cell Infect Microbiol [4.3] 8, 179. doi:10.3389/fcimb.2018.00179
Marchese, L., Nascimento, J.F., Damasceno, F.S., Bringaud, F., Michels, P.A.M., Silber, A.M., (2018). The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids. Pathogens [no IF] 7. doi:10.3390/pathogens7020036
Marquet, S., (2018). Overview of human genetic susceptibility to malaria: From parasitemia control to severe disease. Infect Genet Evol [2.6] 66, 399–409. doi:10.1016/j.meegid.2017.06.001
Millerioux, Y., Mazet, M., Bouyssou, G., Allmann, S., Kiema, T.R., Bertiaux, E., Fouillen, L., Thapa, C., Biran, M., Plazolles, N., Dittrich-Domergue, F., Crouzols, A., Wierenga, R.K., Rotureau, B., Moreau, P., Bringaud, F., (2018). De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions. PLoS Pathog [6.6] 14, e1007116. doi:10.1371/journal.ppat.1007116
Minet, C., Thevenon, S., Chantal, I., Solano, P., Berthier, D., (2018). Mini-review on CRISPR-Cas9 and its potential applications to help controlling neglected tropical diseases caused by Trypanosomatidae. Infect Genet Evol [2.6] 63, 326–331. doi:10.1016/j.meegid.2018.02.030
Morlon-Guyot, J., Berry, L., Sauquet, I., Singh Pall, G., El Hajj, H., Meissner, M., Daher, W., (2018a). Conditional knock-down of a novel coccidian protein leads to the formation of aberrant apical organelles and abrogates mature rhoptry positioning in Toxoplasma gondii. Mol Biochem Parasitol [2.5] 223, 19–30. doi:10.1016/j.molbiopara.2018.06.003
Morlon-Guyot, J., El Hajj, H., Martin, K., Fois, A., Carrillo, A., Berry, L., Burchmore, R., Meissner, M., Lebrun, M., Daher, W., (2018b). A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis. Cell Microbiol [4.4] 20, e12870. doi:10.1111/cmi.12870
Nguyen, H.M., Liu, S., Daher, W., Tan, F., Besteiro, S., (2018). Characterisation of two Toxoplasma PROPPINs homologous to Atg18/WIPI suggests they have evolved distinct specialised functions. PLoS One [2.8] 13, e0195921. doi:10.1371/journal.pone.0195921
Niare, K., Paloque, L., Menard, S., Tor, P., Ramadani, A.P., Augereau, J.M., Dara, A., Berry, A., Benoit-Vical, F., Doumbo, O.K., (2018). Multiple Phenotypic and Genotypic Artemisinin Sensitivity Evaluation of Malian Plasmodium falciparum Isolates. Am J Trop Med Hyg [2.5] 98, 1123–1131. doi:10.4269/ajtmh.17-0798
Pavlou, G., Biesaga, M., Touquet, B., Lagal, V., Balland, M., Dufour, A., Hakimi, M., Tardieux, I., (2018). Toxoplasma Parasite Twisting Motion Mechanically Induces Host Cell Membrane Fission to Complete Invasion within a Protective Vacuole. Cell Host Microbe [14.9] 24, 81-96.e5. doi:10.1016/j.chom.2018.06.003
Pineda, E., Thonnus, M., Mazet, M., Mourier, A., Cahoreau, E., Kulyk, H., Dupuy, J.W., Biran, M., Masante, C., Allmann, S., Riviere, L., Rotureau, B., Portais, J.C., Bringaud, F., (2018). Glycerol supports growth of the Trypanosoma brucei bloodstream forms in the absence of glucose: Analysis of metabolic adaptations on glycerol-rich conditions. PLoS Pathog [6.6] 14, e1007412. doi:10.1371/journal.ppat.1007412
Rchiad, Z., Haidar, M., Ansari, H.R., Tajeri, S., Ben Rached, F., Langsley, G., Pain, A., (2018). GZMA and RASGRP1 are novel tumor suppressors that counter dissemination of Theileria annulata-transformed macrophages. bioRxiv [preprint]. doi:10.1101/338160
Sidorov, P., Davioud-Charvet, E., Marcou, G., Horvath, D., Varnek, A., (2018). AntiMalarial Mode of Action (AMMA) Database: Data Selection, Verification and Chemical Space Analysis. Mol Inform [2.0] 37, e1800021. doi:10.1002/minf.201800021
Silva, M.C., Davoli-Ferreira, M., Medina, T.S., Sesti-Costa, R., Silva, G.K., Lopes, C.D., Cardozo, L.E., Gava, F.N., Lyroni, K., Dias, F.C., Frade, A.F., Baron, M., Nakaya, H.I., Figueiredo, F., Alves-Filho, J.C., Cunha, F.Q., Tsatsanis, C., Chevillard, C., Cunha-Neto, E., Hirsch, E., Silva, J.S., Cunha, T.M., (2018). Canonical PI3Kgamma signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis. Nat Commun [12.1] 9, 1513. doi:10.1038/s41467-018-03986-3
Soleilhac, E., Brillet-Gueguen, L., Roussel, V., Prudent, R., Touquet, B., Dass, S., Aci-Seche, S., Kasam, V., Barette, C., Imberty, A., Breton, V., Vantard, M., Horvath, D., Botte, C., Tardieux, I., Roy, S., Marechal, E., Lafanechere, L., (2018). Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches. Int J Mol Sci [3.7] 19. doi:10.3390/ijms19103085
Song, O.R., Queval, C.J., Iantomasi, R., Delorme, V., Marion, S., Veyron-Churlet, R., Werkmeister, E., Popoff, M., Ricard, I., Jouny, S., Deboosere, N., Lafont, F., Baulard, A., Yeramian, E., Marsollier, L., Hoffmann, E., Brodin, P., (2018). ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton. EMBO Rep [8.6] 19, 29–42. doi:10.15252/embr.201744371
Touquet, B., Pelissier, L., Cavailles, P., Yi, W., Bellini, V., Mercier, C., Cesbron-Delauw, M.F., Boumendjel, A., Aldebert, D., (2018). High-content imaging assay to evaluate Toxoplasma gondii infection and proliferation: A multiparametric assay to screen new compounds. PLoS One [2.8] 13, e0201678. doi:10.1371/journal.pone.0201678
Uboldi, A.D., Wilde, M.L., McRae, E.A., Stewart, R.J., Dagley, L.F., Yang, L., Katris, N.J., Hapuarachchi, S.V., Coffey, M.J., Lehane, A.M., Botte, C.Y., Waller, R.F., Webb, A.I., McConville, M.J., Tonkin, C.J., (2018). Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii. PLoS Biol [9.2] 16, e2005642. doi:10.1371/journal.pbio.2005642
Unlu, A.H., Tajeri, S., Bilgic, H.B., Eren, H., Karagenc, T., Langsley, G., (2018). The secreted Theileria annulata Ta9 protein contributes to activation of the AP-1 transcription factor. PLoS One [2.8] 13, e0196875. doi:10.1371/journal.pone.0196875
Varet, H., Shaulov, Y., Sismeiro, O., Trebicz-Geffen, M., Legendre, R., Coppee, J.Y., Ankri, S., Guillen, N., (2018). Enteric bacteria boost defences against oxidative stress in Entamoeba histolytica. Sci Rep [4.1] 8, 9042. doi:10.1038/s41598-018-27086-w
Wargnies, M., Bertiaux, E., Cahoreau, E., Ziebart, N., Crouzols, A., Morand, P., Biran, M., Allmann, S., Hubert, J., Villafraz, O., Millerioux, Y., Plazolles, N., Asencio, C., Rivière, L., Rotureau, B., Boshart, M., Portais, J.-C., Bringaud, F., (2018). Gluconeogenesis is essential for trypanosome development in the tsetse fly vector. PLoS Pathog [6.6] 14, e1007502. doi:10.1371/journal.ppat.1007502
Wein, S., Ghezal, S., Bure, C., Maynadier, M., Perigaud, C., Vial, H.J., Lefebvre-Tournier, I., Wengelnik, K., Cerdan, R., (2018). Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite. J Lipid Res [4.8] 59, 1461–1471. doi:10.1194/jlr.M085589
Wengelnik, K., Daher, W., Lebrun, M., (2018). Phosphoinositides and their functions in apicomplexan parasites. Int J Parasitol [3.7] 48, 493–504. doi:10.1016/j.ijpara.2018.01.009
Zanghi, G., Vembar, S.S., Baumgarten, S., Ding, S., Guizetti, J., Bryant, J.M., Mattei, D., Jensen, A.T.R., Renia, L., Goh, Y.S., Sauerwein, R., Hermsen, C.C., Franetich, J.F., Bordessoulles, M., Silvie, O., Soulard, V., Scatton, O., Chen, P., Mecheri, S., Mazier, D., Scherf, A., (2018). A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection. Cell Rep [8.3] 22, 2951–2963. doi:10.1016/j.celrep.2018.02.075
Ahouty, B., Koffi, M., Ilboudo, H., Simo, G., Matovu, E., Mulindwa, J., Hertz-Fowler, C., Bucheton, B., Sidibe, I., Jamonneau, V., MacLeod, A., Noyes, H., N’Guetta, S.P., Trypano, G.E.N.R.G. as members of T.H.A.C., (2017). Candidate genes-based investigation of susceptibility to Human African Trypanosomiasis in Cote d’Ivoire. PLoS Negl Trop Dis [3.8] 11, e0005992. doi:10.1371/journal.pntd.0005992
Albisetti, A., Florimond, C., Landrein, N., Vidilaseris, K., Eggenspieler, M., Lesigang, J., Dong, G., Robinson, D.R., Bonhivers, M., (2017). Interaction between the flagellar pocket collar and the hook complex via a novel microtubule-binding protein in Trypanosoma brucei. PLoS Pathog [6.6] 13, e1006710. doi:10.1371/journal.ppat.1006710
Allmann, S., Bringaud, F., (2017). Glycosomes: a comprehensive view on the metabolic role in T. brucei. Int J Biochem Cell Biol [3.9] 85, 85–90. doi:10.1016/j.biocel.2017.01.015
Besteiro, S., (2017). Autophagy in apicomplexan parasites. Curr Opin Microbiol [6.2] 40, 14–20. doi:10.1016/j.mib.2017.10.008
Bonnart, C., Feuillet, G., Vasseur, V., Cenac, N., Vergnolle, N., Blanchard, N., (2017). Protease-Activated Receptor 2 contributes to Toxoplasma gondii-mediated gut inflammation. Parasite Immunol [2.5] 39. doi:10.1111/pim.12489
Boquet-Pujadas, A., Lecomte, T., Manich, M., Thibeaux, R., Labruyere, E., Guillen, N., Olivo-Marin, J.C., Dufour, A.C., (2017). BioFlow: a non-invasive, image-based method to measure speed, pressure and forces inside living cells. Sci Rep [4.3] 7, 9178. doi:10.1038/s41598-017-09240-y
Bossard, G., Bartoli, M., Fardeau, M.L., Holzmuller, P., Ollivier, B., Geiger, A., (2017). Characterization of recombinant Trypanosoma brucei gambiense Translationally Controlled Tumor Protein (rTbgTCTP) and its interaction with Glossina midgut bacteria. Gut Microbes [no IF] 8, 413–427. doi:10.1080/19490976.2017.1331833
Boulange, A., Pillay, D., Chevtzoff, C., Biteau, N., Come de Graca, V., Rempeters, L., Theodoridis, D., Baltz, t., (2017). Development of a rapid antibody test for point-of-care diagnosis of animal African trypanosomosis. Vet Parasitol [2.2] 233, 32–38. doi:10.1016/j.vetpar.2016.11.017
Bryant, J.M., Regnault, C., Scheidig-Benatar, C., Baumgarten, S., Guizetti, J., Scherf, A., (2017). CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for var2csa Gene Activation or Silencing in Plasmodium falciparum. MBio [7.0] 8. doi:10.1128/mBio.00729-17
Buaillon, C., Guerrero, N.A., Cebrian, I., Blanie, S., Lopez, J., Bassot, E., Vasseur, V., Santi-Rocca, J., Blanchard, N., (2017). MHC I presentation of Toxoplasma gondii immunodominant antigen does not require Sec22b and is regulated by antigen orientation at the vacuole membrane. Eur J Immunol [4.2] 47, 1160–1170. doi:10.1002/eji.201646859
Buscher, P., Cecchi, G., Jamonneau, V., Priotto, G., (2017). Human African trypanosomiasis. Lancet [47,8]. doi:10.1016/S0140-6736(17)31510-6
Cabantous, S., Doumbo, O., Poudiougou, B., Louis, L., Barry, A., Oumar, A.A., Traore, A., Marquet, S., Dessein, A., (2017). Gene Expression Analysis Reveals Genes Common to Cerebral Malaria and Neurodegenerative Disorders. J Infect Dis 216, 771–775. doi:10.1093/infdis/jix359
Chan, S., Frasch, A., Mandava, C.S., Ch’ng, J.H., Quintana, M.D.P., Vesterlund, M., Ghorbal, M., Joannin, N., Franzen, O., Lopez-Rubio, J.J., Barbieri, S., Lanzavecchia, A., Sanyal, S., Wahlgren, M., (2017). Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor. Nat Microbiol [no IF] 2, 17068. doi:10.1038/nmicrobiol.2017.68
Cooper, A., Ilboudo, H., Alibu, V.P., Ravel, S., Enyaru, J., Weir, W., Noyes, H., Capewell, P., Camara, M., Milet, J., Jamonneau, V., Camara, O., Matovu, E., Bucheton, B., MacLeod, A., (2017). APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis. eLife [7.7] 6. doi:10.7554/eLife.25461
Courjol, F., Mouveaux, T., Lesage, K., Saliou, J.M., Werkmeister, E., Bonabaud, M., Rohmer, M., Slomianny, C., Lafont, F., Gissot, M., (2017). Characterization of a nuclear pore protein sheds light on the roles and composition of the Toxoplasma gondii nuclear pore complex. Cell Mol Life Sci [5.7] 74, 2107–2125. doi:10.1007/s00018-017-2459-3
Cubi, R., Vembar, S.S., Biton, A., Franetich, J.F., Bordessoulles, M., Sossau, D., Zanghi, G., Bosson-Vanga, H., Benard, M., Moreno, A., Dereuddre-Bosquet, N., Le Grand, R., Scherf, A., Mazier, D., (2017). Laser capture microdissection enables transcriptomic analysis of dividing and quiescent liver stages of Plasmodium relapsing species. Cell Microbiol [4.5] 19. doi:10.1111/cmi.12735
Di Cristina, M., Dou, Z., Lunghi, M., Kannan, G., Huynh, M.H., McGovern, O.L., Schultz, T.L., Schultz, A.J., Miller, A.J., Hayes, B.M., van der Linden, W., Emiliani, C., Bogyo, M., Besteiro, S., Coppens, I., Carruthers, V.B., (2017). Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection. Nat Microbiol [no IF] 2, 17096. doi:10.1038/nmicrobiol.2017.96
Draheim, M., Wlodarczyk, M.F., Crozat, K., Saliou, J.-M., Alayi, T.D., Tomavo, S., Hassan, A., Salvioni, A., Demarta‐Gatsi, C., Sidney, J., Sette, A., Dalod, M., Berry, A., Silvie, O., Blanchard, N., (2017). Profiling MHC II immunopeptidome of blood‐stage malaria reveals that cDC1 control the functionality of parasite‐specific CD4 T cells. EMBO Mol Med [9.2] e201708123. doi:10.15252/emmm.201708123
Ferreira, L.R.P., Ferreira, F.M., Laugier, L., Cabantous, S., Navarro, I.C., da Silva Candido, D., Rigaud, V.C., Real, J.M., Pereira, G.V., Pereira, I.R., Ruivo, L., Pandey, R.P., Savoia, M., Kalil, J., Lannes-Vieira, J., Nakaya, H., Chevillard, C., Cunha-Neto, E., (2017). Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection. Sci Rep [4.3] 7, 17990. doi:10.1038/s41598-017-18080-9
Frenal, K., Dubremetz, J.F., Lebrun, M., Soldati-Favre, D., (2017). Gliding motility powers invasion and egress in Apicomplexa. Nat Rev Microbiol [26.8] 15, 645–660. doi:10.1038/nrmicro.2017.86
Garcia-Silva, M.R., Sollelis, L., MacPherson, C.R., Stanojcic, S., Kuk, N., Crobu, L., Bringaud, F., Bastien, P., Pages, M., Scherf, A., Sterkers, Y., (2017). Identification of the centromeres of Leishmania major: revealing the hidden pieces. EMBO Rep [8.6]. doi:10.15252/embr.201744216
Gissot, M., Hovasse, A., Chaloin, L., Schaeffer-Reiss, C., Van Dorsselaer, A., Tomavo, S., (2017). An evolutionary conserved zinc finger protein is involved in Toxoplasma gondii mRNA nuclear export. Cell Microbiol [4.5] 19. doi:10.1111/cmi.12644
Guerin, A., Corrales, R.M., Parker, M.L., Lamarque, M.H., Jacot, D., El Hajj, H., Soldati-Favre, D., Boulanger, M.J., Lebrun, M., (2017a). Efficient invasion by Toxoplasma depends on the subversion of host protein networks. Nat Microbiol [no IF] 2, 1358–1366. doi:10.1038/s41564-017-0018-1
Guerin, A., El Hajj, H., Penarete-Vargas, D., Besteiro, S., Lebrun, M., (2017b). RON4L1 is a new member of the moving junction complex in Toxoplasma gondii. Sci Rep [4.3] 7, 17907. doi:10.1038/s41598-017-18010-9
Haidar, M., Latre de Late, P., Kennedy, E.J., Langsley, G., (2017a). Cell penetrating peptides to dissect host-pathogen protein-protein interactions in Theileria-transformed leukocytes. Bioorg Med Chem [3.0]. doi:10.1016/j.bmc.2017.08.056
Haidar, M., Lombes, A., Bouillaud, F., Kennedy, E.J., Langsley, G., (2017b). HK2 Recruitment to Phospho-BAD Prevents Its Degradation, Promoting Warburg Glycolysis by Theileria-Transformed Leukocytes. ACS Infect Dis [no IF] 3, 216–224. doi:10.1021/acsinfecdis.6b00180
Haidar, M., Ramdani, G., Kennedy, E.J., Langsley, G., (2017c). PKA and Apicomplexan Parasite Diseases. Horm Metab Res [2.0] 49, 296–300. doi:10.1055/s-0042-118459
Hakimi, M.A., Olias, P., Sibley, L.D., (2017). Toxoplasma Effectors Targeting Host Signaling and Transcription. Clin Microbiol Rev [16.2] 30, 615–645. doi:10.1128/CMR.00005-17
Harijan, R.K., Kiema, T.-R., Syed, S.M., Qadir, I., Mazet, M., Bringaud, F., Michels, P.A.M., Wierenga, R.K., (2017). Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1. Protein Engineering Design and Selection. doi:10.1093/protein/gzw080
Harnett, M.M., Pineda, M.A., Latre de Late, P., Eason, R.J., Besteiro, S., Harnett, W., Langsley, G., (2017). From Christian de Duve to Yoshinori Ohsumi: More to autophagy than just dining at home. Biomed J [no IF] 40, 9–22. doi:10.1016/j.bj.2016.12.004
Jacob, F., Melachio, T.T., Njitchouang, G.R., Gimonneau, G., Njiokou, F., Abate, L., Christen, R., Reveillaud, J., Geiger, A., (2017). Intestinal Bacterial Communities of Trypanosome-Infected and Uninfected Glossina palpalis palpalis from Three Human African Trypanomiasis Foci in Cameroon. Front Microbiol [4.1] 8, 1464. doi:10.3389/fmicb.2017.01464
Jain, V., Yogavel, M., Kikuchi, H., Oshima, Y., Hariguchi, N., Matsumoto, M., Goel, P., Touquet, B., Jumani, R.S., Tacchini-Cottier, F., Harlos, K., Huston, C.D., Hakimi, M.A., Sharma, A., (2017). Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis. Structure [4.9] 25, 1495-1505 e6. doi:10.1016/j.str.2017.07.015
Jannin, J., Solano, P., Quick, I., Debre, P., (2017). The francophone network on neglected tropical diseases. PLoS Negl Trop Dis [3.8] 11, e0005738. doi:10.1371/journal.pntd.0005738
Jida, M., Sanchez, C.P., Urgin, K., Ehrhardt, K., Mounien, S., Geyer, A., Elhabiri, M., Lanzer, M., Davioud-Charvet, E., (2017). A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs. ACS Infect Dis [no IF] 3, 119–131. doi:10.1021/acsinfecdis.5b00141
Kabore, J.W., Ilboudo, H., Noyes, H., Camara, O., Kabore, J., Camara, M., Koffi, M., Lejon, V., Jamonneau, V., MacLeod, A., Hertz-Fowler, C., Belem, A.M.G., Matovu, E., Bucheton, B., Sidibe, I., Trypano, G.E.N.R.G. as members of T.H.A.C., (2017). Candidate gene polymorphisms study between human African trypanosomiasis clinical phenotypes in Guinea. PLoS Negl Trop Dis [3.8] 11, e0005833. doi:10.1371/journal.pntd.0005833
Krieg, R., Jortzik, E., Goetz, A.A., Blandin, S., Wittlin, S., Elhabiri, M., Rahbari, M., Nuryyeva, S., Voigt, K., Dahse, H.M., Brakhage, A., Beckmann, S., Quack, T., Grevelding, C.G., Pinkerton, A.B., Schonecker, B., Burrows, J., Davioud-Charvet, E., Rahlfs, S., Becker, K., (2017). Arylmethylamino steroids as antiparasitic agents. Nat Commun [12.1] 8, 14478. doi:10.1038/ncomms14478
Labruyere, E., Thibeaux, R., Olivo-Marin, J.C., Guillen, N., (2017). Crosstalk between Entamoeba histolytica and the human intestinal tract during amoebiasis. Parasitology [2.6] 1–10. doi:10.1017/S0031182017002190
Lachaud, L., Fernandez-Arevalo, A., Normand, A.C., Lami, P., Nabet, C., Donnadieu, J.L., Piarroux, M., Djenad, F., Cassagne, C., Ravel, C., Tebar, S., Llovet, T., Blanchet, D., Demar, M., Harrat, Z., Aoun, K., Bastien, P., Munoz, C., Gallego, M., Piarroux, R., (2017). Identification of Leishmania by Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) Mass Spectrometry Using a Free Web-Based Application and a Dedicated Mass-Spectral Library. J Clin Microbiol [3.7] 55, 2924–2933. doi:10.1128/JCM.00845-17
Lacombe, S., Bangratz, M., Brizard, J.P., Petitdidier, E., Pagniez, J., Sereme, D., Lemesre, J.L., Brugidou, C., (2017). Optimized transitory ectopic expression of promastigote surface antigen protein in Nicotiana benthamiana, a potential anti-Leishmaniasis vaccine candidate. J Biosci Bioeng [2.2]. doi:10.1016/j.jbiosc.2017.07.008
Latour, C., Wlodarczyk, M.F., Jung, G., Gineste, A., Blanchard, N., Ganz, T., Roth, M.P., Coppin, H., Kautz, L., (2017). Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia. Haematologica [6.7] 102, 60–68. doi:10.3324/haematol.2016.150227
Latre de Late, P., Pineda, M., Harnett, M., Harnett, W., Besteiro, S., Langsley, G., (2017). Apicomplexan autophagy and modulation of autophagy in parasite-infected host cells. Biomed J [no IF] 40, 23–30. doi:10.1016/j.bj.2017.01.001
Laugier, L., Frade, A.F., Ferreira, F.M., Baron, M.A., Teixeira, P.C., Cabantous, S., Ferreira, L.R.P., Louis, L., Rigaud, V.O.C., Gaiotto, F.A., Bacal, F., Pomerantzeff, P., Bocchi, E., Kalil, J., Santos, R.H.B., Cunha-Neto, E., Chevillard, C., (2017). Whole genome Cardiac DNA methylation fingerprint and gene expression analysis provide new insights in the pathogenesis of Chronic Chagas disease Cardiomyopathy. Clin Infect Dis [8.7]. doi:10.1093/cid/cix506
Lebrun, M., Blanchard, N., (2017). Editorial overview: Host-microbe interactions: parasites. Curr. Opin. Microbiol. 40, viii–xi. doi:10.1016/j.mib.2017.11.028
Lentini, G., El Hajj, H., Papoin, J., Fall, G., Pfaff, A.W., Tawil, N., Braun-Breton, C., Lebrun, M., (2017). Characterization of Toxoplasma DegP, a rhoptry serine protease crucial for lethal infection in mice. PLoS One [2.8] 12, e0189556. doi:10.1371/journal.pone.0189556
Leveque, M.F., Berry, L., Yamaryo-Botte, Y., Nguyen, H.M., Galera, M., Botte, C.Y., Besteiro, S., (2017). TgPL2, a patatin-like phospholipase domain-containing protein, is involved in the maintenance of apicoplast lipids homeostasis in Toxoplasma. Mol Microbiol [3.8] 105, 158–174. doi:10.1111/mmi.13694
Mantilla, B.S., Marchese, L., Casas-Sanchez, A., Dyer, N.A., Ejeh, N., Biran, M., Bringaud, F., Lehane, M.J., Acosta-Serrano, A., Silber, A.M., (2017). Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector. PLoS Pathog [6.6] 13, e1006158. doi:10.1371/journal.ppat.1006158
Manzoni, G., Marinach, C., Topcu, S., Briquet, S., Grand, M., Tolle, M., Gransagne, M., Lescar, J., Andolina, C., Franetich, J.F., Zeisel, M.B., Huby, T., Rubinstein, E., Snounou, G., Mazier, D., Nosten, F., Baumert, T.F., Silvie, O., (2017). Plasmodium P36 determines host cell receptor usage during sporozoite invasion. eLife [7.7] 6. doi:10.7554/eLife.25903
Marquet, S., Bucheton, B., Reymond, C., Argiro, L., El-Safi, S.H., Kheir, M.M., Desvignes, J.P., Beroud, C., Mergani, A., Hammad, A., Dessein, A.J., (2017a). Exome sequencing identifies two variants of the alkylglycerol monooxygenase gene (AGMO) as a cause of relapses in visceral Leishmaniasis in children, in Sudan. J Infect Dis [6.3] 216, 22–28. doi:10.1093/infdis/jix277
Marquet, S., Conte, I., Poudiougou, B., Argiro, L., Dessein, H., Couturier, C., Burte, F., Oumar, A.A., Brown, B.J., Traore, A., Afolabi, N.K., Barry, A., Omokhodion, S., Shokunbi, W.A., Sodeinde, O., Doumbo, O., Fernandez-Reyes, D., Dessein, A.J., (2017b). A Functional IL22 Polymorphism (rs2227473) Is Associated with Predisposition to Childhood Cerebral Malaria. Sci Rep [4.3] 7, 41636. doi:10.1038/srep41636
Martins, R.M., Macpherson, C.R., Claes, A., Scheidig-Benatar, C., Sakamoto, H., Yam, X.Y., Preiser, P., Goel, S., Wahlgren, M., Sismeiro, O., Coppee, J.Y., Scherf, A., (2017). An ApiAP2 member regulates expression of clonally variant genes of the human malaria parasite Plasmodium falciparum. Sci Rep [4.3] 7, 14042. doi:10.1038/s41598-017-12578-y
McCall, M.B.B., Wammes, L.J., Langenberg, M.C.C., van Gemert, G.J., Walk, J., Hermsen, C.C., Graumans, W., Koelewijn, R., Franetich, J.F., Chishimba, S., Gerdsen, M., Lorthiois, A., van de Vegte, M., Mazier, D., Bijker, E.M., van Hellemond, J.J., van Genderen, P.J.J., Sauerwein, R.W., (2017). Infectivity of Plasmodium falciparum sporozoites determines emerging parasitemia in infected volunteers. Sci Transl Med [16.8] 9. doi:10.1126/scitranslmed.aag2490
Medina, T.S., Oliveira, G.G., Silva, M.C., David, B.A., Silva, G.K., Fonseca, D.M., Sesti-Costa, R., Frade, A.F., Baron, M.A., Ianni, B., Pereira, A.C., Chevillard, C., Cunha-Neto, E., Marin-Neto, J.A., Silva, J.S., (2017). Ebi3 Prevents Trypanosoma cruzi-Induced Myocarditis by Dampening IFN-γ-Driven Inflammation. Front Immunol [6.4] 8, 1213. doi:10.3389/fimmu.2017.01213
Miliu, A., Lebrun, M., Braun-Breton, C., Lamarque, M.H., (2017). Shelph2, a bacterial-like phosphatase of the malaria parasite Plasmodium falciparum, is dispensable during asexual blood stage. PLoS One [2.8] 12, e0187073. doi:10.1371/journal.pone.0187073
Morlon-Guyot, J., Francia, M.E., Dubremetz, J.F., Daher, W., (2017). Towards a molecular architecture of the centrosome in Toxoplasma gondii. Cytoskeleton [2.2] 74, 55–71. doi:10.1002/cm.21353
N’Djetchi, M.K., Ilboudo, H., Koffi, M., Kabore, J., Kabore, J.W., Kaba, D., Courtin, F., Coulibaly, B., Fauret, P., Kouakou, L., Ravel, S., Deborggraeve, S., Solano, P., De Meeus, T., Bucheton, B., Jamonneau, V., (2017). The study of trypanosome species circulating in domestic animals in two human African trypanosomiasis foci of Cote d’Ivoire identifies pigs and cattle as potential reservoirs of Trypanosoma brucei gambiense. PLoS Negl Trop Dis [3.8] 11, e0005993. doi:10.1371/journal.pntd.0005993
Nguyen, H.M., Berry, L., Sullivan, W.J., Jr., Besteiro, S., (2017a). Autophagy participates in the unfolded protein response in Toxoplasma gondii. FEMS Microbiol Lett [1.8] 364. doi:10.1093/femsle/fnx153
Nguyen, H.M., El Hajj, H., El Hajj, R., Tawil, N., Berry, L., Lebrun, M., Bordat, Y., Besteiro, S., (2017b). Toxoplasma gondii autophagy-related protein ATG9 is crucial for the survival of parasites in their host. Cellular microbiology 19. doi:10.1111/cmi.12712
Nzoumbou-Boko, R., De Muylder, G., Semballa, S., Lecordier, L., Dauchy, F.A., Gobert, A.P., Holzmuller, P., Lemesre, J.L., Bras-Goncalves, R., Barnabe, C., Courtois, P., Daulouede, S., Beschin, A., Pays, E., Vincendeau, P., (2017). Trypanosoma musculi Infection in Mice Critically Relies on Mannose Receptor-Mediated Arginase Induction by a TbKHC1 Kinesin H Chain Homolog. J Immunol [4.9] 199, 1762–1771. doi:10.4049/jimmunol.1700179
Ofon, E., Noyes, H., Mulindwa, J., Ilboudo, H., Simuunza, M., Ebo’o, V., Njiokou, F., Koffi, M., Bucheton, B., Fogue, P., Hertz-Fowler, C., MacLeod, A., Simo, G., TrypanoGen Research Group, as members of T.H.A.C., (2017). A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations. PLoS Negl Trop Dis [3.8] 11, e0005979. doi:10.1371/journal.pntd.0005979
Palencia, A., Bougdour, A., Brenier-Pinchart, M.P., Touquet, B., Bertini, R.L., Sensi, C., Gay, G., Vollaire, J., Josserand, V., Easom, E., Freund, Y.R., Pelloux, H., Rosenthal, P.J., Cusack, S., Hakimi, M.A., (2017). Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis. EMBO Mol Med [9.2] 9, 385–394. doi:10.15252/emmm.201607370
Pegoraro, S., Duffey, M., Otto, T.D., Wang, Y., Rosemann, R., Baumgartner, R., Fehler, S.K., Lucantoni, L., Avery, V.M., Moreno-Sabater, A., Mazier, D., Vial, H.J., Strobl, S., Sanchez, C.P., Lanzer, M., (2017). SC83288 is a clinical development candidate for the treatment of severe malaria. Nat Commun [12.1] 8, 14193. doi:10.1038/ncomms14193
Pellegrini, E., Palencia, A., Braun, L., Kapp, U., Bougdour, A., Belrhali, H., Bowler, M.W., Hakimi, M.-A., (2017). Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist. Structure [4.9] 25, 16–26. doi:10.1016/j.str.2016.10.011
Pineda, E., Perdomo, D., (2017). Entamoeba histolytica under Oxidative Stress: What Countermeasure Mechanisms Are in Place? Cells [5.7] 6. doi:10.3390/cells6040044
Prieto Barja, P., Pescher, P., Bussotti, G., Dumetz, F., Imamura, H., Kedra, D., Domagalska, M., Chaumeau, V., Himmelbauer, H., Pages, M., Sterkers, Y., Dujardin, J.C., Notredame, C., Spath, G.F., (2017). Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani. Nat Ecol Evol [No IF] 1, 1961–1969. doi:10.1038/s41559-017-0361-x
Robert-Gangneux, F., Brenier-Pinchart, M.P., Yera, H., Belaz, S., Varlet-Marie, E., Bastien, P., Molecular Biology Study Group of the French National Reference Center for, T., (2017). Evaluation of Toxoplasma ELITe MGB Real-Time PCR Assay for Diagnosis of Toxoplasmosis. J Clin Microbiol [3.7] 55, 1369–1376. doi:10.1128/JCM.02379-16
Sa, Q., Ochiai, E., Tiwari, A., Mullins, J., Shastri, N., Mercier, C., Cesbron-Delauw, M.F., Suzuki, Y., (2017). Determination of a Key Antigen for Immunological Intervention To Target the Latent Stage of Toxoplasma gondii. J Immunol [4.9] 198, 4425–4434. doi:10.4049/jimmunol.1700062
Santi-Rocca, J., Blanchard, N., (2017). Membrane trafficking and remodeling at the host–parasite interface. Curr Opin Microbiol [6.2] 40, 145–151. doi:10.1016/j.mib.2017.11.013
Shears, M.J., MacRae, J.I., Mollard, V., Goodman, C.D., Sturm, A., Orchard, L.M., Llinas, M., McConville, M.J., Botte, C.Y., McFadden, G.I., (2017). Characterization of the Plasmodium falciparum and P. berghei glycerol 3-phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast. Cell Microbiol [4.5] 19. doi:10.1111/cmi.12633
Shrivastava, S.K., Dalko, E., Delcroix-Genete, D., Herbert, F., Cazenave, P.A., Pied, S., (2017). Uptake of parasite-derived vesicles by astrocytes and microglial phagocytosis of infected erythrocytes may drive neuroinflammation in cerebral malaria. Glia [6.0] 65, 75–92. doi:10.1002/glia.23075
Siciliano, G., Santha Kumar, T.R., Bona, R., Camarda, G., Calabretta, M.M., Cevenini, L., Davioud-Charvet, E., Becker, K., Cara, A., Fidock, D.A., Alano, P., (2017). A high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase-based mature gametocyte assay. Mol Microbiol [3.8] 104, 306–318. doi:10.1111/mmi.13626
Sidorov, P., Viira, B., Davioud-Charvet, E., Maran, U., Marcou, G., Horvath, D., Varnek, A., (2017). QSAR modeling and chemical space analysis of antimalarial compounds. J Comput Aided Mol Des [3.2] 31, 441–451. doi:10.1007/s10822-017-0019-4
Silvie, O., Amino, R., Hafalla, J.C., (2017). Tissue-specific cellular immune responses to malaria pre-erythrocytic stages. Curr Opin Microbiol [6.2] 40, 160–167. doi:10.1016/j.mib.2017.12.001
Sindikubwabo, F., Ding, S., Hussain, T., Ortet, P., Barakat, M., Baumgarten, S., Cannella, D., Palencia, A., Bougdour, A., Belmudes, L., Coute, Y., Tardieux, I., Botte, C.Y., Scherf, A., Hakimi, M.A., (2017). Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites. eLife [7.7] 6. doi:10.7554/eLife.29391
Smith, T., Bringaud, F., Nolan, D., Figueiredo, L., (2017). Metabolic reprogramming during the Trypanosoma brucei life cycle. F1000Research [no IF] 6. doi:10.12688/f1000research.10342.2
Stanojcic, S., Kuk, N., Ullah, I., Sterkers, Y., Merrick, C.J., (2017). Single-molecule analysis reveals that DNA replication dynamics vary across the course of schizogony in the malaria parasite Plasmodium falciparum. Sci Rep [4.3] 7, 4003. doi:10.1038/s41598-017-04407-z
Sundriyal, S., Chen, P.B., Lubin, A.S., Lueg, G.A., Li, F., White, A.J.P., Malmquist, N.A., Vedadi, M., Scherf, A., Fuchter, M.J., (2017). Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity. MedChemCommun [2.3] 8, 1069–1092. doi:10.1039/c7md00052a
Surve, S.V., Jensen, B.C., Heestand, M., Mazet, M., Smith, T.K., Bringaud, F., Parsons, M., Schnaufer, A., (2017). NADH dehydrogenase of Trypanosoma brucei is important for efficient acetate production in bloodstream forms. Mol Biochem Parasitol [2.5] 211, 57–61. doi:10.1016/j.molbiopara.2016.10.001
Thonnus, M., Guerin, A., Riviere, L., (2017). A multigene family encoding surface glycoproteins in Trypanosoma congolense. Microb Cell [no IF] 4, 90–97. doi:10.15698/mic2017.03.562
Urgin, K., Jida, M., Ehrhardt, K., Muller, T., Lanzer, M., Maes, L., Elhabiri, M., Davioud-Charvet, E., (2017). Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties. Molecules [2.5] 22. doi:10.3390/molecules22010161
Venugopal, K., Werkmeister, E., Barois, N., Saliou, J.M., Poncet, A., Huot, L., Sindikubwabo, F., Hakimi, M.A., Langsley, G., Lafont, F., Marion, S., (2017). Dual role of the Toxoplasma gondii clathrin adaptor AP1 in the sorting of rhoptry and microneme proteins and in parasite division. PLoS Pathog [6.6] 13, e1006331. doi:10.1371/journal.ppat.1006331
Volohonsky, G., Hopp, A.K., Saenger, M., Soichot, J., Scholze, H., Boch, J., Blandin, S.A., Marois, E., (2017). Transgenic Expression of the Anti-parasitic Factor TEP1 in the Malaria Mosquito Anopheles gambiae. PLoS Pathog [6.6] 13, e1006113. doi:10.1371/journal.ppat.1006113
Aguilar-Rojas, A., Olivo-Marin, J.C., Guillen, N., (2016). The motility of Entamoeba histolytica: finding ways to understand intestinal amoebiasis. Curr Opin Microbiol [6.2] 34, 24–30. doi:10.1016/j.mib.2016.07.016
Amiar, S., MacRae, J.I., Callahan, D.L., Dubois, D., van Dooren, G.G., Shears, M.J., Cesbron-Delauw, M.F., Marechal, E., McConville, M.J., McFadden, G.I., Yamaryo-Botte, Y., Botte, C.Y., (2016). Apicoplast-Localized Lysophosphatidic Acid Precursor Assembly Is Required for Bulk Phospholipid Synthesis in Toxoplasma gondii and Relies on an Algal/Plant-Like Glycerol 3-Phosphate Acyltransferase. PLoS Pathog [8.1] 12, e1005765. doi:10.1371/journal.ppat.1005765
Bandje, K., Naissant, B., Bigey, P., Lohezic, M., Vayssieres, M., Blaud, M., Kermasson, L., Lopez-Rubio, J.J., Langsley, G., Lavazec, C., Deloron, P., Merckx, A., (2016). Characterization of an A-kinase anchoring protein-like suggests an alternative way of PKA anchoring in Plasmodium falciparum. Malar J [3.1] 15, 248. doi:10.1186/s12936-016-1275-9
Barata, L., Houze, P., Boutbibe, K., Zanghi, G., Franetich, J.F., Mazier, D., Clain, J., (2016). In Vitro Analysis of the Interaction between Atovaquone and Proguanil against Liver Stage Malaria Parasites. Antimicrob Agents Chemother [4.5] 60, 4333–5. doi:10.1128/AAC.01685-15
Barthe, P., Veyron-Churlet, R., de Visch, A., Gilleron, M., Saliou, J.M., Tomavo, S., Nigou, J., Brodin, P., Cohen-Gonsaud, M., (2016). Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization. Structure [5.2] 24, 1788–1794. doi:10.1016/j.str.2016.07.009
Berry, L., Chen, C.T., Reininger, L., Carvalho, T.G., El Hajj, H., Morlon-Guyot, J., Bordat, Y., Lebrun, M., Gubbels, M.J., Doerig, C., Daher, W., (2016). The conserved apicomplexan Aurora kinase TgArk3 is involved in endodyogeny, duplication rate and parasite virulence. Cell Microbiol [4.5] 18, 1106–20. doi:10.1111/cmi.12571
Berthier, D., Breniere, S.F., Bras-Goncalves, R., Lemesre, J.L., Jamonneau, V., Solano, P., Lejon, V., Thevenon, S., Bucheton, B., (2016). Tolerance to Tryoanosomatics: A Threat, or a Key for Disease Elimination? Trends Parasitol. [7.3] 32, 157–168. doi:10.1016/j.pt.2015.11.001
Bieler, S., Waltenberger, H., Barrett, M.P., McCulloch, R., Mottram, J.C., Carrington, M., Schwaeble, W., McKerrow, J., Phillips, M.A., Michels, P.A., Buscher, P., Sanchez, J.C., Bishop, R., Robinson, D.R., Bangs, J., Ferguson, M., Nerima, B., Albertini, A., Michel, G., Radwandska, M., Ndung’u, J.M., (2016). Evaluation of Antigens for Development of a Serological Test for Human African Trypanosomiasis. PLoS One [3.1] 11, e0168074. doi:10.1371/journal.pone.0168074
Biteau, N., Asencio, C., Izotte, J., Rousseau, B., Fevre, M., Pillay, D., Baltz, t., (2016). Trypanosoma brucei gambiense Infections in Mice Lead to Tropism to the Reproductive Organs, and Horizontal and Vertical Transmission. PLoS Negl Trop Dis [3.8] 10, e0004350. doi:10.1371/journal.pntd.0004350
Bouvet, M., Dubois-Deruy, E., Alayi, T.D., Mulder, P., El Amranii, M., Beseme, O., Amouyel, P., Richard, V., Tomavo, S., Pinet, F., (2016). Increased level of phosphorylated desmin and its degradation products in heart failure. Biochemistry and Biophysics Reports [no IF] 6, 54–62. doi:10.1016/j.bbrep.2016.02.014
Bouyer, G., Reininger, L., Ramdani, G., Phillips, L.D., Sharma, V., Egee, S., Langsley, G., Lasonder, E., (2016). Plasmodium falciparum infection induces dynamic changes in the erythrocyte phospho-proteome. Blood Cells Mol Dis [2.7] 58, 35–44. doi:10.1016/j.bcmd.2016.02.001
Bullen, H.E., Jia, Y., Yamaryo-Botte, Y., Bisio, H., Zhang, O., Jemelin, N.K., Marq, J.B., Carruthers, V., Botte, C.Y., Soldati-Favre, D., (2016). Phosphatidic Acid-Mediated Signaling Regulates Microneme Secretion in Toxoplasma. Cell Host Microbe [12.5] 19, 349–60. doi:10.1016/j.chom.2016.02.006
Cebrian, I., Croce, C., Guerrero, N.A., Blanchard, N., Mayorga, L.S., (2016). Rab22a controls MHC‐I intracellular trafficking and antigen cross‐presentation by dendritic cells. EMBO reports [9.1] 17, e201642358. doi:10.15252/embr.201642358
Chen, P.B., Ding, S., Zanghi, G., Soulard, V., DiMaggio, P.A., Fuchter, M.J., Mecheri, S., Mazier, D., Scherf, A., Malmquist, N.A., (2016). Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites. Sci Rep [5.2] 6, 21802. doi:10.1038/srep21802
Cnops, J., Kauffmann, F., De Trez, C., Baltz, t., Keirsse, J., Radwanska, M., Muraille, E., Magez, S., (2016). Maintenance of B cells during chronic murine Trypanosoma brucei gambiense infection. Parasite Immunol [1.9] 38, 642–7. doi:10.1111/pim.12344
Curt-Varesano, A., Braun, L., Ranquet, C., Hakimi, M.A., Bougdour, A., (2016). The aspartyl protease TgASP5 mediates the export of the Toxoplasma GRA16 and GRA24 effectors into host cells. Cell Microbiol [4.5] 18, 151–167. doi:10.1111/cmi.12498
Daher, W., Morlon-Guyot, J., Alayi, T.D., Tomavo, S., Wengelnik, K., Lebrun, M., (2016). Identification of Toxoplasma TgPH1, a pleckstrin homology domain-containing protein that binds to the phosphoinositide PI(3,5)P2. Mol Biochem Parasitol [2.5] 207, 39–44. doi:10.1016/j.molbiopara.2016.03.011
Dalko, E., Genete, D., Auger, F., Dovergne, C., Lambert, C., Herbert, F., Cazenave, P.A., Roland, J., Pied, S., (2016a). Heme dampens T-cell sequestration by modulating glial cell responses during rodent cerebral malaria. Brain Behav Immun [5.9] 58, 280–290. doi:10.1016/j.bbi.2016.07.157
Dalko, E., Tchitchek, N., Pays, L., Herbert, F., Cazenave, P.A., Ravindran, B., Sharma, S., Nataf, S., Das, B., Pied, S., (2016b). Erythropoietin Levels Increase during Cerebral Malaria and Correlate with Heme, Interleukin-10 and Tumor Necrosis Factor-Alpha in India. PLoS One [3.1] 11, e0158420. doi:10.1371/journal.pone.0158420
Dauchy, F.-A., Bonhivers, M., Landrein, N., Dacheux, D., Courtois, P., Lauruol, F., Daulouède, S., Vincendeau, P., Robinson, D.R., (2016). Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model. PLoS Negl Trop Dis [3.8] 10, e0005125. doi:10.1371/journal.pntd.0005125
Drobecq, H., Boll, E., Senechal, M., Desmet, R., Saliou, J.M., Lacapere, J.J., Mougel, A., Vicogne, J., Melnyk, O., (2016). A Central Cysteine Residue Is Essential for the Thermal Stability and Function of SUMO-1 Protein and SUMO-1 Peptide-Protein Conjugates. Bioconjug Chem [4.5] 27, 1540–1546. doi:10.1021/acs.bioconjchem.6b00211
Duffier, Y., Lorthiois, A., Cistero, P., Dupuy, F., Jouvion, G., Fiette, L., Mazier, D., Mayor, A., Lavazec, C., Moreno Sabater, A., (2016). A humanized mouse model for sequestration of Plasmodium falciparum sexual stages and in vivo evaluation of gametocytidal drugs. Sci Rep [5.2] 6, 35025. doi:10.1038/srep35025
Ehrhardt, K., Deregnaucourt, C., Goetz, A.A., Tzanova, T., Gallo, V., Arese, P., Pradines, B., Adjalley, S.H., Bagrel, D., Blandin, S., Lanzer, M., Davioud-Charvet, E., (2016). The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites. Antimicrob Agents Chemother [4.5] 60, 5146–58. doi:10.1128/AAC.02975-15
Fatarova, M., Bellvert, F., Cahoreau, E., Bringaud, F., Portais, J.-C., (2016). Methods to Investigate Metabolic Systems in Trypanosoma, in: Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery. Wiley-VCH Verlag GmbH & Co. KGaA, pp. 295–320. doi:10.1002/9783527694082.ch13
Frade, A.F., Laugier, L., Ferreira, L.R., Baron, M.A., Benvenuti, L.A., Teixeira, P.C., Navarro, I.C., Cabantous, S., Ferreira, F.M., da Silva Candido, D., Gaiotto, F.A., Bacal, F., Pomerantzeff, P., Santos, R.H., Kalil, J., Cunha-Neto, E., Chevillard, C., (2016). Myocardial Infarction-Associated Transcript, a Long Noncoding RNA, Is Overexpressed During Dilated Cardiomyopathy Due to Chronic Chagas Disease. J Infect Dis [6.3] 214, 161–5. doi:10.1093/infdis/jiw095
Gay, G., Braun, L., Brenier-Pinchart, M.P., Vollaire, J., Josserand, V., Bertini, R.L., Varesano, A., Touquet, B., De Bock, P.J., Coute, Y., Tardieux, I., Bougdour, A., Hakimi, M.A., (2016). Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-gamma-mediated host defenses. J Exp Med [11.2] 213, 1779–1798. doi:10.1084/jem.20160340
Guizetti, J., Barcons-Simon, A., Scherf, A., (2016). Trans-acting GC-rich non-coding RNA at var expression site modulates gene counting in malaria parasite. Nucleic Acids Res [8.6] 44, 9710–9718. doi:10.1093/nar/gkw664
Harijan, R.K., Mazet, M., Kiema, T.R., Bouyssou, G., Alexson, S.E.H., Bergmann, U., Moreau, P., Michels, P.A.M., Bringaud, F., Wierenga, R.K., (2016). The SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolism. Proteins [2.5] 84, 1075–1096. doi:10.1002/prot.25054
Leveque, M.F., Berry, L., Besteiro, S., (2016). An evolutionarily conserved SSNA1/DIP13 homologue is a component of both basal and apical complexes of Toxoplasma gondii. Sci Rep [5.2] 6, 27809. doi:10.1038/srep27809
Mariotti-Ferrandiz, E., Pham, H.P., Dulauroy, S., Gorgette, O., Klatzmann, D., Cazenave, P.A., Pied, S., Six, A., (2016). A TCRbeta Repertoire Signature Can Predict Experimental Cerebral Malaria. PLoS One [3.1] 11, e0147871. doi:10.1371/journal.pone.0147871
Menard, S., Tchoufack, J.N., Maffo, C.N., Nsango, S.E., Iriart, X., Abate, L., Tsapi, M.T., Awono-Ambene, P.H., Abega Mekongo, F.A., Morlais, I., Berry, A., (2016). Insight into k13-propeller gene polymorphism and ex vivo DHA-response profiles from Cameroonian isolates. Malar J [3.1] 15, 572. doi:10.1186/s12936-016-1622-x
Morse, D., Webster, W., Kalanon, M., Langsley, G., McFadden, G.I., (2016). Plasmodium falciparum Rab1A Localizes to Rhoptries in Schizonts. PLoS One [3.1] 11, e0158174. doi:10.1371/journal.pone.0158174
Odongo, S., Sterckx, Y.G., Stijlemans, B., Pillay, D., Baltz, t., Muyldermans, S., Magez, S., (2016). An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase. PLoS Negl Trop Dis [3.8] 10, e0004420. doi:10.1371/journal.pntd.0004420
Panda, A.K., Das, B.K., Panda, A., Tripathy, R., Pattnaik, S.S., Mahto, H., Pied, S., Pathak, S., Sharma, S., Ravindran, B., (2016). Heterozygous mutants of TIRAP (S180L) polymorphism protect adult patients with Plasmodium falciparum infection against severe disease and mortality. Infect Genet Evol [2.6] 43, 146–50. doi:10.1016/j.meegid.2016.04.035
Parker, M.L., Penarete-Vargas, D.M., Hamilton, P.T., Guerin, A., Dubey, J.P., Perlman, S.J., Spano, F., Lebrun, M., Boulanger, M.J., (2016). Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair. Proc Natl Acad Sci U S A [9.4] 113, 398–403. doi:10.1073/pnas.1515898113
Peng, K., Goh, Y.S., Siau, A., Franetich, J.F., Chia, W.N., Ong, A.S., Malleret, B., Wu, Y.Y., Snounou, G., Hermsen, C.C., Adams, J.H., Mazier, D., Preiser, P.R., Sauerwein, R.W., Gruner, A.C., Renia, L., (2016). Breadth of humoral response and antigenic targets of sporozoite-inhibitory antibodies associated with sterile protection induced by controlled human malaria infection. Cell Microbiol [4.5] 18, 1739–1750. doi:10.1111/cmi.12608
Perdomo, D., Bonhivers, M., Robinson, D.R., (2016a). The Trypanosome Flagellar Pocket Collar and Its Ring Forming Protein-TbBILBO1. Cells [no IF] 5. doi:10.3390/cells5010009
Perdomo, D., Manich, M., Syan, S., Olivo-Marin, J.C., Dufour, A.C., Guillen, N., (2016b). Intracellular traffic of the lysine and glutamic acid rich protein KERP1 reveals features of endomembrane organization in Entamoeba histolytica. Cell Microbiol [4.5] 18, 1134–1152. doi:10.1111/cmi.12576
Petropolis, D.B., Faust, D.M., Tolle, M., Riviere, L., Valentin, T., Neuveut, C., Hernandez-Cuevas, N., Dufour, A., Olivo-Marin, J.C., Guillen, N., (2016). Human Liver Infection in a Dish: Easy-To-Build 3D Liver Models for Studying Microbial Infection. PLoS One [3.1] 11, e0148667. doi:10.1371/journal.pone.0148667
Rastogi, R., Verma, J.K., Kapoor, A., Langsley, G., Mukhopadhyay, A., (2016). Rab5 Isoforms Specifically Regulate Different Modes of Endocytosis in Leishmania. J Biol Chem [4.3] 291, 14732–46. doi:10.1074/jbc.M116.716514
Rodo, E.C., Feng, L., Jida, M., Ehrhardt, K., Bielitza, M., Boilevin, J., Lanzer, M., Williams, D.L., Lanfranchi, D.A., Davioud-Charvet, E., (2016). A Platform of Regioselective Methodologies to Access Polysubstituted 2-Methyl-1,4-naphthoquinone Derivatives: Scope and Limitations. European Journal of Organic Chemistry [3.1] 2016, 1982–1993. doi:10.1002/ejoc.201600144
Rommereim, L.M., Bellini, V., Fox, B.A., Petre, G., Rak, C., Touquet, B., Aldebert, D., Dubremetz, J.F., Cesbron-Delauw, M.F., Mercier, C., Bzik, D.J., (2016). Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (GRA2-9) in Virulent Toxoplasma gondii. PLoS One [3.1] 11, e0159306. doi:10.1371/journal.pone.0159306
Sakura, T., Sindikubwabo, F., Oesterlin, L.K., Bousquet, H., Slomianny, C., Hakimi, M.A., Langsley, G., Tomavo, S., (2016). A Critical Role for Toxoplasma gondii Vacuolar Protein Sorting VPS9 in Secretory Organelle Biogenesis and Host Infection. Sci Rep [5.2] 6, 38842. doi:10.1038/srep38842
Sanecka, A., Yoshida, N., Dougan, S.K., Jackson, J., Shastri, N., Ploegh, H., Blanchard, N., Frickel, E.M., (2016). Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute-phase Toxoplasma gondii burden. Immunology [4.1] 149, 270–279. doi:10.1111/imm.12643
Sangare, L.O., Alayi, T.D., Westermann, B., Hovasse, A., Sindikubwabo, F., Callebaut, I., Werkmeister, E., Lafont, F., Slomianny, C., Hakimi, M.A., Van Dorsselaer, A., Schaeffer-Reiss, C., Tomavo, S., (2016). Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection. Nat Commun [11.3] 7, 11191. doi:10.1038/ncomms11191
Sengupta, A., Ghosh, S., Das, B.K., Panda, A., Tripathy, R., Pied, S., Ravindran, B., Pathak, S., Sharma, S., Sonawat, H.M., (2016). Host metabolic responses to Plasmodium falciparum infections evaluated by 1H NMR metabolomics. Mol Biosyst [2.9] 12, 3324–3332. doi:10.1039/c6mb00362a
Sidorov, P., Desta, I., Chesse, M., Horvath, D., Marcou, G., Varnek, A., Davioud-Charvet, E., Elhabiri, M., (2016). Redox Polypharmacology as an Emerging Strategy to Combat Malarial Parasites. ChemMedChem [3.0] 11, 1339–1351. doi:10.1002/cmdc.201600009
Souza, M.A., Almeida, T.M., Castro, M.C., Oliveira-Mendes, A.P., Almeida, A.F., Oliveira, B.C., Rocha, L.F., Medeiros, A.C., Brito, M.E., Dessein, A.J., Pereira, V.R., (2016). American tegumentary Leishmaniasis: mRNA expression for Th1 and Treg mediators are predominant in patients with recent active disease. Immunobiology [2.8] 221, 253–9. doi:10.1016/j.imbio.2015.08.009
Stafkova, J., Mach, J., Biran, M., Verner, Z., Bringaud, F., Tachezy, J., (2016). Mitochondrial pyruvate carrier in Trypanosoma brucei. Mol Microbiol [3.8] 100, 442–56. doi:10.1111/mmi.13325
Stanojcic, S., Sollelis, L., Kuk, N., Crobu, L., Balard, Y., Schwob, E., Bastien, P., Pages, M., Sterkers, Y., (2016). Single-molecule analysis of DNA replication reveals novel features in the divergent eukaryotes Leishmania and Trypanosoma brucei versus mammalian cells. Sci Rep [5.2] 6, 23142. doi:10.1038/srep23142
Tetaud, E., Lefebvre, M., M’Bang-Benet, D.E., Crobu, L., Blancard, C., Sterkers, Y., Pages, M., Bastien, P., Merlin, G., (2016). TbFlabarin, a flagellar protein of Trypanosoma brucei, highlights differences between Leishmania and Trypanosoma flagellar-targeting signals. Exp Parasitol [1.6] 166, 97–107. doi:10.1016/j.exppara.2016.04.004
Vembar, S.S., Droll, D., Scherf, A., (2016a). Translational regulation in blood stages of the malaria parasite Plasmodium spp.: systems-wide studies pave the way. Wiley Interdiscip Rev RNA [4.5] 7, 772–792. doi:10.1002/wrna.1365
Vembar, S.S., Seetin, M., Lambert, C., Nattestad, M., Schatz, M.C., Baybayan, P., Scherf, A., Smith, M.L., (2016b). Complete telomere-to-telomere de novo assembly of the Plasmodium falciparum genome through long-read (>11 kb), single molecule, real-time sequencing. DNA Res [5.3] 23, 339–51. doi:10.1093/dnares/dsw022
Viira, B., Gendron, T., Lanfranchi, D.A., Cojean, S., Horvath, D., Marcou, G., Varnek, A., Maes, L., Maran, U., Loiseau, P.M., Davioud-Charvet, E., (2016). In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids. Molecules [2.5] 21. doi:10.3390/molecules21070853
Wang, K., Peng, E.D., Huang, A.S., Xia, D., Vermont, S.J., Lentini, G., Lebrun, M., Wastling, J.M., Bradley, P.J., (2016). Identification of Novel O-Linked Glycosylated Toxoplasma Proteins by Vicia villosa Lectin Chromatography. PLoS One [3.1] 11, e0150561. doi:10.1371/journal.pone.0150561
Weber, C., Koutero, M., Dillies, M.A., Varet, H., Lopez-Camarillo, C., Coppee, J.Y., Hon, C.C., Guillen, N., (2016). Extensive transcriptome analysis correlates the plasticity of Entamoeba histolytica pathogenesis to rapid phenotype changes depending on the environment. Sci Rep [5.2] 6, 35852. doi:10.1038/srep35852
Austen, J.M., Reid, S.A., Robinson, D.R., Friend, J.A., Ditcham, W.G., Irwin, P.J., Ryan, U., (2015). Investigation of the morphological diversity of the potentially zoonotic Trypanosoma copemani in quokkas and Gilbert’s potoroos. Parasitology [2.6] 142, 1443–52. doi:10.1017/S0031182015000785
Berthier, D., Peylhard, M., Dayo, G.K., Flori, L., Sylla, S., Bolly, S., Sakande, H., Chantal, I., Thevenon, S., (2015). A comparison of phenotypic traits related to trypanotolerance in five west african cattle breeds highlights the value of shorthorn taurine breeds. PLoS One [3.2] 10, e0126498. doi:10.1371/journal.pone.0126498
Bielitza, M., Belorgey, D., Ehrhardt, K., Johann, L., Lanfranchi, D.A., Gallo, V., Schwarzer, E., Mohring, F., Jortzik, E., Williams, D.L., Becker, K., Arese, P., Elhabiri, M., Davioud-Charvet, E., (2015). Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats. Antioxid Redox Signal [7.7] 22, 1337–51. doi:10.1089/ars.2014.6047
Bittame, A., Effantin, G., Petre, G., Ruffiot, P., Travier, L., Schoehn, G., Weissenhorn, W., Cesbron-Delauw, M.F., Gagnon, J., Mercier, C., (2015). Toxoplasma gondii: biochemical and biophysical characterization of recombinant soluble dense granule proteins GRA2 and GRA6. Biochem Biophys Res Commun [2.3] 459, 107–12. doi:10.1016/j.bbrc.2015.02.078
Blanc, A.L., Keswani, T., Gorgette, O., Bandeira, A., Malissen, B., Cazenave, P.A., Pied, S., (2015). Suppression of CD4+ Effector Responses by Naturally Occurring CD4+ CD25+ Foxp3+ Regulatory T Cells Contributes to Experimental Cerebral Malaria. Infect Immun [3.7] 84, 329–38. doi:10.1128/IAI.00717-15
Blanchard, N., Dunay, I.R., Schluter, D., (2015). Persistence of Toxoplasma gondii in the central nervous system: a fine-tuned balance between the parasite, the brain and the immune system. Parasite Immunol [1.8] 37, 150–8. doi:10.1111/pim.12173
Bringaud, F., Biran, M., Millerioux, Y., Wargnies, M., Allmann, S., Mazet, M., (2015). Combining reverse genetics and nuclear magnetic resonance-based metabolomics unravels trypanosome-specific metabolic pathways. Mol Microbiol [4.4] 96, 917–26. doi:10.1111/mmi.12990
Bringaud, Frédéric, Rogers, M., Ghedin, E., (2015). Identification and Analysis of Ingi-Related Retroposons in the Trypanosomatid Genomes, in: Peacock, C. (Ed.), Parasite Genomics Protocols, Methods in Molecular Biology. Springer New York, New York, NY, pp. 109–122. doi:10.1007/978-1-4939-1438-8_6
Castelli, E.C., Mendes-Junior, C.T., Sabbagh, A., Porto, I.O., Garcia, A., Ramalho, J., Lima, T.H., Massaro, J.D., Dias, F.C., Collares, C.V., Jamonneau, V., Bucheton, B., Camara, M., Donadi, E.A., (2015). HLA-E coding and 3’ untranslated region variability determined by next-generation sequencing in two West-African population samples. Hum Immunol [2.1] 76, 945–53. doi:10.1016/j.humimm.2015.06.016
Contet, A., Pihan, E., Lavigne, M., Wengelnik, K., Maheshwari, S., Vial, H., Douguet, D., Cerdan, R., (2015). Plasmodium falciparum CTP: phosphocholine cytidylyltransferase possesses two functional catalytic domains and is inhibited by a CDP-choline analog selected from a virtual screening. FEBS Lett [3.2] 589, 992–1000. doi:10.1016/j.febslet.2015.03.003
Courtin, F., Camara, M., Rayaisse, J.B., Kagbadouno, M., Dama, E., Camara, O., Traore, I.S., Rouamba, J., Peylhard, M., Somda, M.B., Leno, M., Lehane, M.J., Torr, S.J., Solano, P., Jamonneau, V., Bucheton, B., (2015). Reducing Human-Tsetse Contact Significantly Enhances the Efficacy of Sleeping Sickness Active Screening Campaigns: A Promising Result in the Context of Elimination. PLoS Negl Trop Dis [4.5] 9, e0003727. doi:10.1371/journal.pntd.0003727
Creek, D.J., Mazet, M., Achcar, F., Anderson, J., Kim, D.H., Kamour, R., Morand, P., Millerioux, Y., Biran, M., Kerkhoven, E.J., Chokkathukalam, A., Weidt, S.K., Burgess, K.E., Breitling, R., Watson, D.G., Bringaud, F., Barrett, M.P., (2015). Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose. PLoS Pathog [7.6] 11, e1004689. doi:10.1371/journal.ppat.1004689
Daher, W., Morlon-Guyot, J., Sheiner, L., Lentini, G., Berry, L., Tawk, L., Dubremetz, J.F., Wengelnik, K., Striepen, B., Lebrun, M., (2015). Lipid kinases are essential for apicoplast homeostasis in Toxoplasma gondii. Cell Microbiol [4.8] 17, 559–78. doi:10.1111/cmi.12383
Dalko, E., Das, B., Herbert, F., Fesel, C., Pathak, S., Tripathy, R., Cazenave, P.A., Ravindran, B., Sharma, S., Pied, S., (2015). Multifaceted Role of Heme during Severe Plasmodium falciparum Infections in India. Infect Immun [3.7] 83, 3793–9. doi:10.1128/IAI.00531-15
Doerig, C., Rayner, J.C., Scherf, A., Tobin, A.B., (2015). Post-translational protein modifications in malaria parasites. Nat Rev Microbiol [23.3] 13, 160–72. doi:10.1038/nrmicro3402
Dufour, A.C., Olivo-Marin, J.C., Guillen, N., (2015). Amoeboid movement in protozoan pathogens. Semin Cell Dev Biol [6.3] 46, 128–34. doi:10.1016/j.semcdb.2015.10.010
Elhabiri, M., Sidorov, P., Cesar-Rodo, E., Marcou, G., Lanfranchi, D.A., Davioud-Charvet, E., Horvath, D., Varnek, A., (2015). Electrochemical properties of substituted 2-methyl-1,4-naphthoquinones: redox behavior predictions. Chemistry [5.7] 21, 3415–24. doi:10.1002/chem.201403703
Faust, D.M., Guillen, N., (2015). Cell-Surface Molecules as Virulence Determinants in Entamoeba histolytica, in: Nozaki, T., Bhattacharya, A. (Eds.), Amebiasis: Biology and Pathogenesis of Entamoeba. Springer Japan, Tokyo, pp. 243–262. doi:10.1007/978-4-431-55200-0_15
Florimond, C., Sahin, A., Vidilaseris, K., Dong, G., Landrein, N., Dacheux, D., Albisetti, A., Byard, E.H., Bonhivers, M., Robinson, D.R., (2015). BILBO1 is a scaffold protein of the flagellar pocket collar in the pathogen Trypanosoma brucei. PLoS Pathog [7.6] 11, e1004654. doi:10.1371/journal.ppat.1004654
Gendron, T., Kessedjian, H., Davioud-Charvet, E., Lanfranchi, D.A., (2015). Diastereoselective Synthesis of 2,6-Diaryltetrahydrothiopyran-4-ones by Phase-Transfer Catalysis. Eur. J. Org. Chem. 2015, 1790–1796. doi:10.1002/ejoc.201403516
Gold, D.A., Kaplan, A.D., Lis, A., Bett, G.C., Rosowski, E.E., Cirelli, K.M., Bougdour, A., Sidik, S.M., Beck, J.R., Lourido, S., Egea, P.F., Bradley, P.J., Hakimi, M.A., Rasmusson, R.L., Saeij, J.P., (2015). The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole. Cell Host Microbe [12.3] 17, 642–52. doi:10.1016/j.chom.2015.04.003
Guiyedi, V., Becavin, C., Herbert, F., Gray, J., Cazenave, P.A., Kombila, M., Crisanti, A., Fesel, C., Pied, S., (2015). Asymptomatic Plasmodium falciparum infection in children is associated with increased auto-antibody production, high IL-10 plasma levels and antibodies to merozoite surface protein 3. Malar J [3.5] 14, 162. doi:10.1186/s12936-015-0658-7
Haidar, M., Echebli, N., Ding, Y., Kamau, E., Langsley, G., (2015). Transforming growth factor beta2 promotes transcription of COX2 and EP4, leading to a prostaglandin E2-driven autostimulatory loop that enhances virulence of Theileria annulata-transformed macrophages. Infect Immun [3.7] 83, 1869–80. doi:10.1128/IAI.02975-14
Haidar, Malak, Whitworth, J., Noé, G., Liu, W.Q., Vidal, M., Langsley, G., (2015). TGF-β2 induces Grb2 to recruit PI3-K to TGF-RII that activates JNK/AP-1-signaling and augments invasiveness of Theileria-transformed macrophages. Sci Rep [5.6] 5, 15688. doi:10.1038/srep15688
Hakimi, M.A., Bougdour, A., (2015). Toxoplasma’s ways of manipulating the host transcriptome via secreted effectors. Curr Opin Microbiol [7.2] 26, 24–31. doi:10.1016/j.mib.2015.04.003
Hamidou Soumana, I., Klopp, C., Ravel, S., Nabihoudine, I., Tchicaya, B., Parrinello, H., Abate, L., Rialle, S., Geiger, A., (2015). RNA-seq de novo Assembly Reveals Differential Gene Expression in Glossina palpalis gambiensis Infected with Trypanosoma brucei gambiense vs. Non-Infected and Self-Cured Flies. Front Microbiol [4.0] 6, 1259. doi:10.3389/fmicb.2015.01259
Herbert, F., Tchitchek, N., Bansal, D., Jacques, J., Pathak, S., Becavin, C., Fesel, C., Dalko, E., Cazenave, P.A., Preda, C., Ravindran, B., Sharma, S., Das, B., Pied, S., (2015). Evidence of IL-17, IP-10, and IL-10 involvement in multiple-organ dysfunction and IL-17 pathway in acute renal failure associated to Plasmodium falciparum malaria. J Transl Med [3.9] 13, 369. doi:10.1186/s12967-015-0731-6
Hon, C.-C., Weber, C., Koutero, M., Deloger, M., Coppee, J.-Y., Guillen, N., (2015). Surveying Entamoeba histolytica Transcriptome Using Massively Parallel cDNA Sequencing, in: Nozaki, T., Bhattacharya, A. (Eds.), Amebiasis: Biology and Pathogenesis of Entamoeba. Springer Japan, Tokyo, pp. 99–117. doi:10.1007/978-4-431-55200-0_7
Ilboudo, H., Camara, O., Ravel, S., Bucheton, B., Lejon, V., Camara, M., Kabore, J., Jamonneau, V., Deborggraeve, S., (2015). Trypanosoma brucei gambiense Spliced Leader RNA Is a More Specific Marker for Cure of Human African Trypanosomiasis Than T. b. gambiense DNA. J Infect Dis [6.0] 212, 1996–8. doi:10.1093/infdis/jiv337
Jain, V., Yogavel, M., Oshima, Y., Kikuchi, H., Touquet, B., Hakimi, M.A., Sharma, A., (2015). Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis. Structure [5.6] 23, 819–29. doi:10.1016/j.str.2015.02.011
Johann, L., Belorgey, D., Huang, H.-H., Day, L., Chessé, M., Becker, K., Williams, D.L., Davioud-Charvet, E., (2015). Synthesis and evaluation of 1, 4–naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs. FEBS J [4.0] 282, 3199–3217. doi:10.1111/febs.13359
Lasonder, E., Green, J.L., Grainger, M., Langsley, G., Holder, A.A., (2015). Extensive differential protein phosphorylation as intraerythrocytic Plasmodium falciparum schizonts develop into extracellular invasive merozoites. Proteomics [3.8] 15, 2716–2729. doi:10.1002/pmic.201400508
Lentini, G., Kong-Hap, M., El Hajj, H., Francia, M., Claudet, C., Striepen, B., Dubremetz, J.F., Lebrun, M., (2015). Identification and characterization of Toxoplasma SIP, a conserved apicomplexan cytoskeleton protein involved in maintaining the shape, motility and virulence of the parasite. Cell Microbiol [4.8] 17, 62–78. doi:10.1111/cmi.12337
Lévêque, M.F., Berry, L., Cipriano, M.J., Nguyen, H.-M., Striepen, B., Besteiro, S., (2015). Autophagy-Related Protein ATG8 Has a Noncanonical Function for Apicoplast Inheritance in Toxoplasma gondii. mBio [6.8] 6, e01446-15. doi:10.1128/mBio.01446-15
Lopez, J., Bittame, A., Massera, C., Vasseur, V., Effantin, G., Valat, A., Buaillon, C., Allart, S., Fox, B.A., Rommereim, L.M., Bzik, D.J., Schoehn, G., Weissenhorn, W., Dubremetz, J.F., Gagnon, J., Mercier, C., Cesbron-Delauw, M.F., Blanchard, N., (2015). Intravacuolar Membranes Regulate CD8 T Cell Recognition of Membrane-Bound Toxoplasma gondii Protective Antigen. Cell Rep [7.2] 13, 2273–86. doi:10.1016/j.celrep.2015.11.001
Lucas-Hourani, M., Munier-Lehmann, H., El Mazouni, F., Malmquist, N.A., Harpon, J., Coutant, E.P., Guillou, S., Helynck, O., Noel, A., Scherf, A., Phillips, M.A., Tangy, F., Vidalain, P.O., Janin, Y.L., (2015). Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH). J Med Chem [5.5] 58, 5579–98. doi:10.1021/acs.jmedchem.5b00606
MacPherson, C.R., Scherf, A., (2015). Flexible guide-RNA design for CRISPR applications using Protospacer Workbench. Nat Biotechnol [39.1] 33, 805–6. doi:10.1038/nbt.3291
Malmquist, N.A., Sundriyal, S., Caron, J., Chen, P., Witkowski, B., Menard, D., Suwanarusk, R., Renia, L., Nosten, F., Jimenez-Diaz, M.B., Angulo-Barturen, I., Santos Martinez, M., Ferrer, S., Sanz, L.M., Gamo, F.J., Wittlin, S., Duffy, S., Avery, V.M., Ruecker, A., Delves, M.J., Sinden, R.E., Fuchter, M.J., Scherf, A., (2015). Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans. Antimicrob Agents Chemother [4.5] 59, 950–9. doi:10.1128/AAC.04419-14
Marquet, S., Conte, I., Poudiougou, B., Argiro, L., Cabantous, S., Dessein, H., Burte, F., Oumar, A.A., Brown, B.J., Traore, A., Afolabi, N.K., Barry, A., Omokhodion, S., Ndoumbe, U.E., Shokunbi, W.A., Sodeinde, O., Doumbo, O., Fernandez-Reyes, D., Dessein, A.J., (2015). The IL17F and IL17RA Genetic Variants Increase Risk of Cerebral Malaria in Two African Populations. Infect Immun [3.7] 84, 590–7. doi:10.1128/IAI.00671-15
Mbang-Benet, D.E., Sterkers, Y., Crobu, L., Sarrazin, A., Bastien, P., Pages, M., (2015). RNA interference screen reveals a high proportion of mitochondrial proteins essential for correct cell cycle progress in Trypanosoma brucei. BMC Genomics [4.0] 16, 297. doi:10.1186/s12864-015-1505-5
Mbengue, A., Bhattacharjee, S., Pandharkar, T., Liu, H., Estiu, G., Stahelin, R.V., Rizk, S.S., Njimoh, D.L., Ryan, Y., Chotivanich, K., Nguon, C., Ghorbal, M., Lopez-Rubio, J.J., Pfrender, M., Emrich, S., Mohandas, N., Dondorp, A.M., Wiest, O., Haldar, K., (2015). A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria. Nature [41.5] 520, 683–7. doi:10.1038/nature14412
Mercier, C., Cesbron-Delauw, M.F., (2015). Toxoplasma secretory granules: one population or more? Trends Parasitol [6.2] 31, 60–71. doi:10.1016/j.pt.2014.12.002
Metheni, M., Lombes, A., Bouillaud, F., Batteux, F., Langsley, G., (2015). HIF-1alpha induction, proliferation and glycolysis of Theileria-infected leukocytes. Cell Microbiol [4.8] 17, 467–72. doi:10.1111/cmi.12421
Mohanty, S., Kennedy, E.J., Herberg, F.W., Hui, R., Taylor, S.S., Langsley, G., Kannan, N., (2015). Structural and evolutionary divergence of cyclic nucleotide binding domains in eukaryotic pathogens: Implications for drug design. Biochim Biophys Acta – Prot Proteom [2.8] 1854, 1575–85. doi:10.1016/j.bbapap.2015.03.012
Morelle, C., Sterkers, Y., Crobu, L., DE, M.B.-B., Kuk, N., Portales, P., Bastien, P., Pages, M., Lachaud, L., (2015). The nucleoporin Mlp2 is involved in chromosomal distribution during mitosis in Trypanosomatids. Nucleic Acids Res [8.8] 43, 4013–27. doi:10.1093/nar/gkv056
Morlon-Guyot, J., Pastore, S., Berry, L., Lebrun, M., Daher, W., (2015). Toxoplasma gondii Vps11, a subunit of HOPS and CORVET tethering complexes, is essential for the biogenesis of secretory organelles. Cell Microbiol [4.8] 17, 1157–78. doi:10.1111/cmi.12426
Nacer, A., Claes, A., Roberts, A., Scheidig-Benatar, C., Sakamoto, H., Ghorbal, M., Lopez-Rubio, J.J., Mattei, D., (2015). Discovery of a novel and conserved Plasmodium falciparum exported protein that is important for adhesion of PfEMP1 at the surface of infected erythrocytes. Cell Microbiol [4.8] 17, 1205–16. doi:10.1111/cmi.12430
Neafsey, D.E., Waterhouse, R.M., Abai, M.R., Aganezov, S.S., Alekseyev, M.A., Allen, J.E., Amon, J., Arca, B., Arensburger, P., Artemov, G., Assour, L.A., Basseri, H., Berlin, A., Birren, B.W., Blandin, S.A., Brockman, A.I., Burkot, T.R., Burt, A., Chan, C.S., Chauve, C., Chiu, J.C., Christensen, M., Costantini, C., Davidson, V.L., Deligianni, E., Dottorini, T., Dritsou, V., Gabriel, S.B., Guelbeogo, W.M., Hall, A.B., Han, M.V., Hlaing, T., Hughes, D.S., Jenkins, A.M., Jiang, X., Jungreis, I., Kakani, E.G., Kamali, M., Kemppainen, P., Kennedy, R.C., Kirmitzoglou, I.K., Koekemoer, L.L., Laban, N., Langridge, N., Lawniczak, M.K., Lirakis, M., Lobo, N.F., Lowy, E., MacCallum, R.M., Mao, C., Maslen, G., Mbogo, C., McCarthy, J., Michel, K., Mitchell, S.N., Moore, W., Murphy, K.A., Naumenko, A.N., Nolan, T., Novoa, E.M., O’Loughlin, S., Oringanje, C., Oshaghi, M.A., Pakpour, N., Papathanos, P.A., Peery, A.N., Povelones, M., Prakash, A., Price, D.P., Rajaraman, A., Reimer, L.J., Rinker, D.C., Rokas, A., Russell, T.L., Sagnon, N., Sharakhova, M.V., Shea, T., Simao, F.A., Simard, F., Slotman, M.A., Somboon, P., Stegniy, V., Struchiner, C.J., Thomas, G.W., Tojo, M., Topalis, P., Tubio, J.M., Unger, M.F., Vontas, J., Walton, C., Wilding, C.S., Willis, J.H., Wu, Y.C., Yan, G., Zdobnov, E.M., Zhou, X., Catteruccia, F., Christophides, G.K., Collins, F.H., Cornman, R.S., Crisanti, A., Donnelly, M.J., Emrich, S.J., Fontaine, M.C., Gelbart, W., Hahn, M.W., Hansen, I.A., Howell, P.I., Kafatos, F.C., Kellis, M., Lawson, D., Louis, C., Luckhart, S., Muskavitch, M.A., Ribeiro, J.M., Riehle, M.A., Sharakhov, I.V., Tu, Z., Zwiebel, L.J., Besansky, N.J., (2015). Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes. Science [31.5] 347, 1258522. doi:10.1126/science.1258522
Perdomo, D., Ait-Ammar, N., Syan, S., Sachse, M., Jhingan, G.D., Guillen, N., (2015). Cellular and proteomics analysis of the endomembrane system from the unicellular Entamoeba histolytica. J Proteomics [3.9] 112, 125–40. doi:10.1016/j.jprot.2014.07.034
Ramdani, G., Naissant, B., Thompson, E., Breil, F., Lorthiois, A., Dupuy, F., Cummings, R., Duffier, Y., Corbett, Y., Mercereau-Puijalon, O., Vernick, K., Taramelli, D., Baker, D.A., Langsley, G., Lavazec, C., (2015). cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. PLoS Pathog [7.6] 11, e1004815. doi:10.1371/journal.ppat.1004815
Risco-Castillo, V., Topçu, S., Marinach, C., Manzoni, G., Bigorgne, A.E., Briquet, S., Baudin, X., Lebrun, M., Dubremetz, J.-F., Silvie, O., (2015). Malaria Sporozoites Traverse Host Cells within Transient Vacuoles. Cell Host Microbe [12.3] 18, 593–603. doi:10.1016/j.chom.2015.10.006
Ruan, J., Mouveaux, T., Light, S.H., Minasov, G., Anderson, W.F., Tomavo, S., Ngo, H.M., (2015). The structure of bradyzoite-specific enolase from Toxoplasma gondii reveals insights into its dual cytoplasmic and nuclear functions. Acta Crystallogr. D Biol. Crystallog [7.2] 71, 417–26. doi:10.1107/S1399004714026479
Rugarabamu, G., Marq, J.B., Guerin, A., Lebrun, M., Soldati-Favre, D., (2015). Distinct contribution of Toxoplasma gondii rhomboid proteases 4 and 5 to micronemal protein protease 1 activity during invasion. Mol Microbiol [4.4] 97, 244–62. doi:10.1111/mmi.13021
Sanchez, E., Perrone, T., Recchimuzzi, G., Cardozo, I., Biteau, N., Aso, P.M., Mijares, A., Baltz, t., Berthier, D., Balzano-Nogueira, L., Gonzatti, M.I., (2015). Molecular characterization and classification of Trypanosoma spp. Venezuelan isolates based on microsatellite markers and kinetoplast maxicircle genes. Parasit Vectors [3.4] 8, 536. doi:10.1186/s13071-015-1129-2
Santos, F., Nequiz, M., Hernandez-Cuevas, N.A., Hernandez, K., Pineda, E., Encalada, R., Guillen, N., Luis-Garcia, E., Saralegui, A., Saavedra, E., Perez-Tamayo, R., Olivos-Garcia, A., (2015). Maintenance of intracellular hypoxia and adequate heat shock response are essential requirements for pathogenicity and virulence of Entamoeba histolytica. Cell Microbiol [4.8] 17, 1037–51. doi:10.1111/cmi.12419
Shears, M.J., Botte, C.Y., McFadden, G.I., (2015). Fatty acid metabolism in the Plasmodium apicoplast: Drugs, doubts and knockouts. Mol Biochem Parasitol [1.8] 199, 34–50. doi:10.1016/j.molbiopara.2015.03.004
Silvestre, A., Plaze, A., Berthon, P., Thibeaux, R., Guillen, N., Labruyère, E., (2015). In Entamoeba histolytica, a BspA family protein is required for chemotaxis toward tumour necrosis factor. Microb Cell [no IF] 2, 235–246. doi:10.15698/mic2015.07.214
Sloves, P.J., Mouveaux, T., Ait-Yahia, S., Vorng, H., Everaere, L., Sangare, L.O., Tsicopoulos, A., Tomavo, S., (2015). Apical Organelle Secretion by Toxoplasma Controls Innate and Adaptive Immunity and Mediates Long-Term Protection. J Infect Dis [6.0] 212, 1449–58. doi:10.1093/infdis/jiv250
Sollelis, L., Ghorbal, M., MacPherson, C.R., Martins, R.M., Kuk, N., Crobu, L., Bastien, P., Scherf, A., Lopez-Rubio, J.J., Sterkers, Y., (2015). First efficient CRISPR-Cas9-mediated genome editing in Leishmania parasites. Cell Microbiol [4.8] 17, 1405–12. doi:10.1111/cmi.12456
Soulard, V., Bosson-Vanga, H., Lorthiois, A., Roucher, C., Franetich, J.F., Zanghi, G., Bordessoulles, M., Tefit, M., Thellier, M., Morosan, S., Le Naour, G., Capron, F., Suemizu, H., Snounou, G., Moreno-Sabater, A., Mazier, D., (2015). Plasmodium falciparum full life cycle and Plasmodium ovale liver stages in humanized mice. Nat Commun [11.5] 6, 7690. doi:10.1038/ncomms8690
Tomavo, S., (2015). Too Much Sugar Puts a Parasite in Jeopardy. Cell Host Microbe [12.3] 18, 641–3. doi:10.1016/j.chom.2015.11.013
van Rooyen, J.M., Hakimi, M.A., Belrhali, H., (2015). Recombinant expression, purification, and crystallization of the glutaminyl-tRNA synthetase from Toxoplasma gondii. Protein Expres Purif [1.5] 110, 115–21. doi:10.1016/j.pep.2015.02.017
Vanwalleghem, G., Fontaine, F., Lecordier, L., Tebabi, P., Klewe, K., Nolan, D.P., Yamaryo-Botte, Y., Botte, C., Kremer, A., Burkard, G.S., Rassow, J., Roditi, I., Perez-Morga, D., Pays, E., (2015). Coupling of lysosomal and mitochondrial membrane permeabilization in trypanolysis by APOL1. Nat Commun [11.5] 6, 8078. doi:10.1038/ncomms9078
Vembar, S.S., Macpherson, C.R., Sismeiro, O., Coppee, J.Y., Scherf, A., (2015). The PfAlba1 RNA-binding protein is an important regulator of translational timing in Plasmodium falciparum blood stages. Genome Biol [10.8] 16, 212. doi:10.1186/s13059-015-0771-5
Volohonsky, G., Terenzi, O., Soichot, J., Naujoks, D.A., Nolan, T., Windbichler, N., Kapps, D., Smidler, A.L., Vittu, A., Costa, G., Steinert, S., Levashina, E.A., Blandin, S.A., Marois, E., (2015). Tools for Anopheles gambiae Transgenesis. G3-Genes Genomes Genet [3.2] 5, 1151–63. doi:10.1534/g3.115.016808
Zhang, Q., Scherf, A., (2015). RNase II: A new player enters the game. RNA Biol [5.0] 12, 586–9. doi:10.1080/15476286.2015.1038013
Allmann, S., Mazet, M., Ziebart, N., Bouyssou, G., Fouillen, L., Dupuy, J.W., Bonneu, M., Moreau, P., Bringaud, F., Boshart, M., (2014). Triacylglycerol Storage in Lipid Droplets in Procyclic Trypanosoma brucei. PLoS One [3.5] 9, e114628. doi:10.1371/journal.pone.0114628
Bonhivers, M., Robinson, D.R., (2014). Tackling trypanosomes. International innovation: Mapping Medecine 80–82. http://www.internationalinnovation.com/mapping-medicine/Albi
Bougdour, A., Tardieux, I., Hakimi, M.A., (2014). Toxoplasma exports dense granule proteins beyond the vacuole to the host cell nucleus and rewires the host genome expression. Cell Microbiol [4.8] 16, 334–43. doi:10.1111/cmi.12255
Boulila, Y., Tomavo, S., Gissot, M., (2014). A RGG motif protein is involved in Toxoplasma gondii stress-mediated response. Mol Biochem Parasitol [2.2] 196, 1–8. doi:10.1016/j.molbiopara.2014.07.009
Bras-Goncalves, R., Petitdidier, E., Pagniez, J., Veyrier, R., Cibrelus, P., Cavaleyra, M., Maquaire, S., Moreaux, J., Lemesre, J.L., (2014). Identification and characterization of new Leishmania promastigote surface antigens, LaPSA-38S and LiPSA-50S, as major immunodominant excreted/secreted components of L. amazonensis and L. infantum. Infect Genet Evol [3.3] 24, 1–14. doi:10.1016/j.meegid.2014.02.017
Cannella, D., Brenier-Pinchart, M.P., Braun, L., van Rooyen, J.M., Bougdour, A., Bastien, O., Behnke, M.S., Curt, R.L., Curt, A., Saeij, J.P., Sibley, L.D., Pelloux, H., Hakimi, M.A., (2014). miR-146a and miR-155 delineate a MicroRNA fingerprint associated with Toxoplasma persistence in the host brain. Cell Rep [7.2] 6, 928–37. doi:10.1016/j.celrep.2014.02.002
Cavailles, P., Flori, P., Papapietro, O., Bisanz, C., Lagrange, D., Pilloux, L., Massera, C., Cristinelli, S., Jublot, D., Bastien, O., Loeuillet, C., Aldebert, D., Touquet, B., Fournie, G.J., Cesbron-Delauw, M.F., (2014). A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage. PLoS Pathog [8.1] 10, e1004005. doi:10.1371/journal.ppat.1004005
Chamakh-Ayari, R., Bras-Goncalves, R., Bahi-Jaber, N., Petitdidier, E., Markikou-Ouni, W., Aoun, K., Moreno, J., Carrillo, E., Salotra, P., Kaushal, H., Negi, N.S., Arevalo, J., Falconi-Agapito, F., Privat, A., Cruz, M., Pagniez, J., Papierok, G.M., Rhouma, F.B., Torres, P., Lemesre, J.L., Chenik, M., Meddeb-Garnaoui, A., (2014). In vitro evaluation of a soluble Leishmania promastigote surface antigen as a potential vaccine candidate against human Leishmaniasis. PLoS One [3.5] 9, e92708. doi:10.1371/journal.pone.0092708
Coppens, I., Asai, T., Tomavo, S., (2014). Chapter 8 - Biochemistry and Metabolism of Toxoplasma gondii: Carbohydrates, Lipids and Nucleotides, in: Toxoplasma gondii (Second Edition). Academic Press, Boston, pp. 257–295. doi:10.1016/B978-0-12-396481-6.00008-8
Cunha-Neto, E., Chevillard, C., (2014). Chagas disease cardiomyopathy: immunopathology and genetics. Mediators Inflamm [2.4] 2014, 683230. doi:10.1155/2014/683230
Dawn, A., Singh, S., More, K.R., Siddiqui, F.A., Pachikara, N., Ramdani, G., Langsley, G., Chitnis, C.E., (2014). The central role of cAMP in regulating Plasmodium falciparum merozoite invasion of human erythrocytes. PLoS Pathog [8.1] 10, e1004520. doi:10.1371/journal.ppat.1004520
Degardin, M., Wein, S., Duckert, J.F., Maynadier, M., Guy, A., Durand, T., Escale, R., Vial, H., Vo-Hoang, Y., (2014). Development of the first oral bioprecursors of bis-alkylguanidine antimalarial drugs. ChemMedChem [3.2] 9, 300–4. doi:10.1002/cmdc.201300419
Dembele, L., Franetich, J.F., Lorthiois, A., Gego, A., Zeeman, A.M., Kocken, C.H., Le Grand, R., Dereuddre-Bosquet, N., van Gemert, G.J., Sauerwein, R., Vaillant, J.C., Hannoun, L., Fuchter, M.J., Diagana, T.T., Malmquist, N.A., Scherf, A., Snounou, G., Mazier, D., (2014). Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures. Nat Med [28.1] 20, 307–12. doi:10.1038/nm.3461
Deramchia, K., Morand, P., Biran, M., Millerioux, Y., Mazet, M., Wargnies, M., Franconi, J.M., Bringaud, F., (2014). Contribution of pyruvate phosphate dikinase in the maintenance of the glycosomal ATP/ADP balance in the Trypanosoma brucei procyclic form. J Biol Chem [4.6] 289, 17365–78. doi:10.1074/jbc.M114.567230
Echebli, N., Mhadhbi, M., Chaussepied, M., Vayssettes, C., Di Santo, J.P., Darghouth, M.A., Langsley, G., (2014). Engineering attenuated virulence of a Theileria annulata-infected macrophage. PLoS Negl Trop Dis [4.5] 8, e3183. doi:10.1371/journal.pntd.0003183
Ezougou, C.N., Ben-Rached, F., Moss, D.K., Lin, J.W., Black, S., Knuepfer, E., Green, J.L., Khan, S.M., Mukhopadhyay, A., Janse, C.J., Coppens, I., Yera, H., Holder, A.A., Langsley, G., (2014). Plasmodium falciparum Rab5B is an N-terminally myristoylated Rab GTPase that is targeted to the parasite’s plasma and food vacuole membranes. PLoS One [3.5] 9, e87695. doi:10.1371/journal.pone.0087695
Ferreira, L.R., Frade, A.F., Baron, M.A., Navarro, I.C., Kalil, J., Chevillard, C., Cunha-Neto, E., (2014a). Interferon-gamma and other inflammatory mediators in cardiomyocyte signaling during Chagas disease cardiomyopathy. World J Cardiol [2.1] 6, 782–90. doi:10.4330/wjc.v6.i8.782
Ferreira, L.R., Frade, A.F., Santos, R.H., Teixeira, P.C., Baron, M.A., Navarro, I.C., Benvenuti, L.A., Fiorelli, A.I., Bocchi, E.A., Stolf, N.A., Chevillard, C., Kalil, J., Cunha-Neto, E., (2014b). MicroRNAs miR-1, miR-133a, miR-133b, miR-208a and miR-208b are dysregulated in Chronic Chagas disease Cardiomyopathy. Int J Cardiol [6.2] 175, 409–17. doi:10.1016/j.ijcard.2014.05.019
Ghorbal, M., Gorman, M., Macpherson, C.R., Martins, R.M., Scherf, A., Lopez-Rubio, J.J., (2014). Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system. Nat Biotechnol [39.1] 32, 819–21. doi:10.1038/nbt.2925
Grover, H.S., Chu, H.H., Kelly, F.D., Yang, S.J., Reese, M.L., Blanchard, N., Gonzalez, F., Chan, S.W., Boothroyd, J.C., Shastri, N., Robey, E.A., (2014). Impact of regulated secretion on antiparasitic CD8 T cell responses. Cell Rep [7.2] 7, 1716–1728. doi:10.1016/j.celrep.2014.04.031
Guillen, N., (2014). Infection biology: Nibbled to death. Nature [42.3] 508, 462–3. doi:10.1038/nature13223
Guillen, N., Duraisingh, M., (2014). Editorial overview: Host-microbe interactions: parasites: sensing and responding to the changing environment: the life of protozoan parasites. Curr Opin Microbiol [7.2] 20, vii–ix. doi:10.1016/j.mib.2014.07.003
Ibrahim, N., Ibrahim, H., Dormoi, J., Briolant, S., Pradines, B., Moreno, A., Mazier, D., Legrand, P., Nepveu, F., (2014). Albumin-bound nanoparticles of practically water-insoluble antimalarial lead greatly enhance its efficacy. Int J Pharm [3.8] 464, 214–24. doi:10.1016/j.ijpharm.2014.01.001
Ilboudo, H., Bras-Goncalves, R., Camara, M., Flori, L., Camara, O., Sakande, H., Leno, M., Petitdidier, E., Jamonneau, V., Bucheton, B., (2014). Unravelling human trypanotolerance: IL8 is associated with infection control whereas IL10 and TNFalpha are associated with subsequent disease development. PLoS Pathog [8.1] 10, e1004469. doi:10.1371/journal.ppat.1004469
Jortzik, E., Farhadi, M., Ahmadi, R., Toth, K., Lohr, J., Helmke, B.M., Kehr, S., Unterberg, A., Ott, I., Gust, R., Deborde, V., Davioud-Charvet, E., Reau, R., Becker, K., Herold-Mende, C., (2014). Antiglioma activity of GoPI-sugar, a novel gold(I)-phosphole inhibitor: chemical synthesis, mechanistic studies, and effectiveness in vivo. Biochim Biophys Acta – Prot Proteom [3.2] 1844, 1415–26. doi:10.1016/j.bbapap.2014.01.006
Lachaud, L., Bourgeois, N., Kuk, N., Morelle, C., Crobu, L., Merlin, G., Bastien, P., Pages, M., Sterkers, Y., (2014). Constitutive mosaic aneuploidy is a unique genetic feature widespread in the Leishmania genus. Microbes Infect [2.7] 16, 61–6. doi:10.1016/j.micinf.2013.09.005
Lamarque, M.H., Roques, M., Kong-Hap, M., Tonkin, M.L., Rugarabamu, G., Marq, J.B., Penarete-Vargas, D.M., Boulanger, M.J., Soldati-Favre, D., Lebrun, M., (2014). Plasticity and redundancy among AMA-RON pairs ensure host cell entry of Toxoplasma parasites. Nat Commun [10.7] 5, 4098. doi:10.1038/ncomms5098
Lavogina, D., Budu, A., Enkvist, E., Hopp, C.S., Baker, D.A., Langsley, G., Garcia, C.R., Uri, A., (2014). Targeting Plasmodium falciparum protein kinases with adenosine analogue-oligoarginine conjugates. Exp Parasitol [1.9] 138, 55–62. doi:10.1016/j.exppara.2014.02.001
Lebrun, M., Carruthers, V.B., Cesbron-Delauw, M.-F., (2014). Chapter 12 - Toxoplasma Secretory Proteins and Their Roles in Cell Invasion and Intracellular Survival, in: Toxoplasma gondii (Second Edition) - The Model Apicomplexan : Perspectives and Methods. Academic Press, Boston, pp. 389–453. doi:10.1016/B978-0-12-396481-6.00012-X
Manzoni, G., Briquet, S., Risco-Castillo, V., Gaultier, C., Topcu, S., Ivanescu, M.L., Franetich, J.F., Hoareau-Coudert, B., Mazier, D., Silvie, O., (2014). A rapid and robust selection procedure for generating drug-selectable marker-free recombinant malaria parasites. Sci Rep [5.1] 4, 4760. doi:10.1038/srep04760
Martin-Benlloch, X., Elhabiri, M., Lanfranchi, D.A., Davioud-Charvet, E., (2014). A practical and economical high-yielding six steps-sequence synthesis of a flavone: Application to the multigram scale synthesis of ladanein. Org Process Res Dev [2.6] 18, 613–617. doi:10.1021/op4003642
Metheni, M., Echebli, N., Chaussepied, M., Ransy, C., Chereau, C., Jensen, K., Glass, E., Batteux, F., Bouillaud, F., Langsley, G., (2014). The level of H(2)O(2) type oxidative stress regulates virulence of Theileria-transformed leukocytes. Cell Microbiol [4.8] 16, 269–79. doi:10.1111/cmi.12218
Mfotie Njoya, E., Weber, C., Hernandez-Cuevas, N.A., Hon, C.C., Janin, Y., Kamini, M.F., Moundipa, P.F., Guillen, N., (2014). Bioassay-guided fractionation of extracts from Codiaeum variegatum against Entamoeba histolytica discovers compounds that modify expression of ceramide biosynthesis related genes. PLoS Negl Trop Dis [4.5] 8, e2607. doi:10.1371/journal.pntd.0002607
Morlon-Guyot, J., Berry, L., Chen, C.T., Gubbels, M.J., Lebrun, M., Daher, W., (2014). The Toxoplasma gondii calcium-dependent protein kinase 7 is involved in early steps of parasite division and is crucial for parasite survival. Cell Microbiol [4.8] 16, 95–114. doi:10.1111/cmi.12186
Mouveaux, T., Oria, G., Werkmeister, E., Slomianny, C., Fox, B.A., Bzik, D.J., Tomavo, S., (2014). Nuclear glycolytic enzyme enolase of Toxoplasma gondii functions as a transcriptional regulator. PLoS One [3.5] 9, e105820. doi:10.1371/journal.pone.0105820
Nagy, G.N., Marton, L., Contet, A., Ozohanics, O., Ardelean, L.M., Revesz, A., Vekey, K., Irimie, F.D., Vial, H., Cerdan, R., Vertessy, B.G., (2014). Composite aromatic boxes for enzymatic transformations of quaternary ammonium substrates. Angew Chem Int Ed Engl [11.3] 53, 13471–6. doi:10.1002/anie.201408246
N’Dilimabaka, N., Taoufiq, Z., Zougbede, S., Bonnefoy, S., Lorthiois, A., Couraud, P.O., Rebollo, A., Snounou, G., Mazier, D., Moreno Sabater, A., (2014). P. falciparum isolate-specific distinct patterns of induced apoptosis in pulmonary and brain endothelial cells. PLoS One [3.5] 9, e90692. doi:10.1371/journal.pone.0090692
Penarete-Vargas, D.M., Boisson, A., Urbach, S., Chantelauze, H., Peyrottes, S., Fraisse, L., Vial, H.J., (2014). A chemical proteomics approach for the search of pharmacological targets of the antimalarial clinical candidate albitiazolium in Plasmodium falciparum using photocrosslinking and click chemistry. PLoS One [3.5] 9, e113918. doi:10.1371/journal.pone.0113918
Petropolis, D.B., Faust, D.M., Deep Jhingan, G., Guillen, N., (2014). A new human 3D-liver model unravels the role of galectins in liver infection by the parasite Entamoeba histolytica. PLoS Pathog [8.1] 10, e1004381. doi:10.1371/journal.ppat.1004381
Peyrottes, S., Caldarelli, S., Wein, S., Perigaud, C., Vial, H., (2014). Exploring prodrug approaches for albitiazolium and its analogues. Curr Top Med Chem [3.5] 14, 1653–67. doi:10.2174/1568026614666140808121746
Risco-Castillo, V., Topcu, S., Son, O., Briquet, S., Manzoni, G., Silvie, O., (2014). CD81 is required for rhoptry discharge during host cell invasion by Plasmodium yoelii sporozoites. Cell Microbiol [4.8] 16, 1533–48. doi:10.1111/cmi.12309
Ronga, L., Del Favero, M., Cohen, A., Soum, C., Le Pape, P., Savrimoutou, S., Pinaud, N., Mullie, C., Daulouede, S., Vincendeau, P., Farvacques, N., Agnamey, P., Pagniez, F., Hutter, S., Azas, N., Sonnet, P., Guillon, J., (2014). Design, synthesis and biological evaluation of novel 4-alkapolyenylpyrrolo[1,2-a]quinoxalines as antiLeishmanial agents--part III. Eur J Med Chem [3.4] 81, 378–93. doi:10.1016/j.ejmech.2014.05.037
Sahin, A., Asencio, C., Izotte, J., Pillay, D., Coustou, V., Karembe, H., Baltz, t., (2014). The susceptibility of Trypanosoma congolense and Trypanosoma brucei to isometamidium chloride and its synthetic impurities. Vet Parasitol [2.7] 203, 270–5. doi:10.1016/j.vetpar.2014.04.002
Saidani, N., Botte, C.Y., Deligny, M., Bonneau, A.L., Reader, J., Lasselin, R., Merer, G., Niepceron, A., Brossier, F., Cintrat, J.C., Rousseau, B., Birkholtz, L.M., Cesbron-Delauw, M.F., Dubremetz, J.F., Mercier, C., Vial, H., Lopez, R., Marechal, E., (2014). Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs. Antimicrob Agents Chemother [4.5] 58, 2586–97. doi:10.1128/AAC.01445-13
Sterkers, Y., Crobu, L., Lachaud, L., Pages, M., Bastien, P., (2014). Parasexuality and mosaic aneuploidy in Leishmania: alternative genetics. Trends Parasitol [6.2] 30, 429–35. doi:10.1016/j.pt.2014.07.002
Thibeaux, R., Ave, P., Bernier, M., Morcelet, M., Frileux, P., Guillen, N., Labruyere, E., (2014). The parasite Entamoeba histolytica exploits the activities of human matrix metalloproteinases to invade colonic tissue. Nat Commun [10.7] 5, 5142. doi:10.1038/ncomms6142
Tomavo, S., (2014). Evolutionary repurposing of endosomal systems for apical organelle biogenesis in Toxoplasma gondii. Int J Parasitol [3.4] 44, 133–8. doi:10.1016/j.ijpara.2013.10.003
van Rooyen, J.M., Murat, J.B., Hammoudi, P.M., Kieffer-Jaquinod, S., Coute, Y., Sharma, A., Pelloux, H., Belrhali, H., Hakimi, M.A., (2014). Assembly of the novel five-component apicomplexan multi-aminoacyl-tRNA synthetase complex is driven by the hybrid scaffold protein Tg-p43. PLoS One [3.5] 9, e89487. doi:10.1371/journal.pone.0089487
van Schaijk, B.C., Ploemen, I.H., Annoura, T., Vos, M.W., Foquet, L., van Gemert, G.J., Chevalley-Maurel, S., van de Vegte-Bolmer, M., Sajid, M., Franetich, J.F., Lorthiois, A., Leroux-Roels, G., Meuleman, P., Hermsen, C.C., Mazier, D., Hoffman, S.L., Janse, C.J., Khan, S.M., Sauerwein, R.W., (2014). A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites. Elife [8.5] 3. doi:10.7554/eLife.03582
Varela, M.L., Razakandrainibe, R., Aldebert, D., Barale, J.C., Jambou, R., (2014). Cytometric measurement of in vitro inhibition of Plasmodium falciparum field isolates by drugs: a new approach for re-invasion inhibition study. Malar J [3.5] 13, 110. doi:10.1186/1475-2875-13-110
Wein, S., Tran Van Ba, C., Maynadier, M., Bordat, Y., Perez, J., Peyrottes, S., Fraisse, L., Vial, H.J., (2014). New insight into the mechanism of accumulation and intraerythrocytic compartmentation of albitiazolium, a new type of antimalarial. Antimicrob Agents Chemother [4.5] 58, 5519–27. doi:10.1128/AAC.00040-14
Witola, W.H., Liu, S.R., Montpetit, A., Welti, R., Hypolite, M., Roth, M., Zhou, Y., Mui, E., Cesbron-Delauw, M.F., Fournie, G.J., Cavailles, P., Bisanz, C., Boyer, K., Withers, S., Noble, A.G., Swisher, C.N., Heydemann, P.T., Rabiah, P., Muench, S.P., McLeod, R., (2014). ALOX12 in human toxoplasmosis. Infect Immun [4.2] 82, 2670–9. doi:10.1128/IAI.01505-13
Zhang, Q., Siegel, T.N., Martins, R.M., Wang, F., Cao, J., Gao, Q., Cheng, X., Jiang, L., Hon, C.C., Scheidig-Benatar, C., Sakamoto, H., Turner, L., Jensen, A.T., Claes, A., Guizetti, J., Malmquist, N.A., Scherf, A., (2014). Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria. Nature [42.3] 513, 431–5. doi:10.1038/nature13468
Allmann, S., Morand, P., Ebikeme, C., Gales, L., Biran, M., Hubert, J., Brennand, A., Mazet, M., Franconi, J.M., Michels, P.A., Portais, J.C., Boshart, M., Bringaud, F., (2013). Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux. J Biol Chem [4.6] 288, 18494–505. doi:10.1074/jbc.M113.462978
Ammar, Z., Plazolles, N., Baltz, t., Coustou, V., (2013). Identification of trans-sialidases as a common mediator of endothelial cell activation by African trypanosomes. PLoS Pathog [8.1] 9, e1003710. doi:10.1371/journal.ppat.1003710
Azzouz, N., Kamena, F., Laurino, P., Kikkeri, R., Mercier, C., Cesbron-Delauw, M.F., Dubremetz, J.F., De Cola, L., Seeberger, P.H., (2013). Toxoplasma gondii secretory proteins bind to sulfated heparin structures. Glycobiology [3.7] 23, 106–20. doi:10.1093/glycob/cws134
Belorgey, D., Lanfranchi, D.A., Davioud-Charvet, E., (2013). 1,4-naphthoquinones and other NADPH-dependent glutathione reductase-catalyzed redox cyclers as antimalarial agents. Curr Pharm Des [3.3] 19, 2512–28. doi:10.2174/1381612811319140003
Braun, L., Brenier-Pinchart, M.P., Yogavel, M., Curt-Varesano, A., Curt-Bertini, R.L., Hussain, T., Kieffer-Jaquinod, S., Coute, Y., Pelloux, H., Tardieux, I., Sharma, A., Belrhali, H., Bougdour, A., Hakimi, M.A., (2013). A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation. J Exp Med [13.9] 210, 2071–86. doi:10.1084/jem.20130103
Caldarelli, S.A., El Fangour, S., Wein, S., Tran van Ba, C., Perigaud, C., Pellet, A., Vial, H.J., Peyrottes, S., (2013). New bis-thiazolium analogues as potential antimalarial agents: design, synthesis, and biological evaluation. J Med Chem [5.3] 56, 496–509. doi:10.1021/jm3014585
Davioud-Charvet, E., (2013). Opinion on “Drug Discovery in Infectious Diseases, Volume 3: Parasitic Helminths: Targets, Screens, Drugs and Vaccines. Edited by Conor R. Caffrey.” ChemMedChem [3.2] 8, 164–166. doi:10.1002/cmdc.201200515
De Muylder, G., Daulouede, S., Lecordier, L., Uzureau, P., Morias, Y., Van Den Abbeele, J., Caljon, G., Herin, M., Holzmuller, P., Semballa, S., Courtois, P., Vanhamme, L., Stijlemans, B., De Baetselier, P., Barrett, M.P., Barlow, J.L., McKenzie, A.N., Barron, L., Wynn, T.A., Beschin, A., Vincendeau, P., Pays, E., (2013). A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity. PLoS Pathog [8.1] 9, e1003731. doi:10.1371/journal.ppat.1003731
Ehrhardt, K., Davioud-Charvet, E., Ke, H., Vaidya, A.B., Lanzer, M., Deponte, M., (2013). The antimalarial activities of methylene blue and the 1,4-naphthoquinone 3-[4-(trifluoromethyl)benzyl]-menadione are not due to inhibition of the mitochondrial electron transport chain. Antimicrob Agents Chemother [4.5] 57, 2114–20. doi:10.1128/AAC.02248-12
Feliu, V., Vasseur, V., Grover, H.S., Chu, H.H., Brown, M.J., Wang, J., Boyle, J.P., Robey, E.A., Shastri, N., Blanchard, N., (2013). Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite. PLoS Pathog [8.1] 9, e1003449. doi:10.1371/journal.ppat.1003449
Frade, A.F., Pissetti, C.W., Ianni, B.M., Saba, B., Lin-Wang, H.T., Nogueira, L.G., de Melo Borges, A., Buck, P., Dias, F., Baron, M., Ferreira, L.R., Schmidt, A., Marin-Neto, J.A., Hirata, M., Sampaio, M., Fragata, A., Pereira, A.C., Donadi, E., Kalil, J., Rodrigues, V., Cunha-Neto, E., Chevillard, C., (2013a). Genetic susceptibility to Chagas disease cardiomyopathy: involvement of several genes of the innate immunity and chemokine-dependent migration pathways. BMC Infect Dis [2.6] 13, 587. doi:10.1186/1471-2334-13-587
Frade, A.F., Teixeira, P.C., Ianni, B.M., Pissetti, C.W., Saba, B., Wang, L.H., Kuramoto, A., Nogueira, L.G., Buck, P., Dias, F., Giniaux, H., Llored, A., Alves, S., Schmidt, A., Donadi, E., Marin-Neto, J.A., Hirata, M., Sampaio, M., Fragata, A., Bocchi, E.A., Stolf, A.N., Fiorelli, A.I., Santos, R.H., Rodrigues, V., Pereira, A.C., Kalil, J., Cunha-Neto, E., Chevillard, C., (2013b). Polymorphism in the alpha cardiac muscle actin 1 gene is associated to susceptibility to chronic inflammatory cardiomyopathy. PLoS One [3.5] 8, e83446. doi:10.1371/journal.pone.0083446
Gendron, T., Lanfranchi, D.A., Davioud-Charvet, E., (2013). Redox-Active Agents in Reactions Involving the Trypanothione/Trypanothione Reductase-based System to Fight Kinetoplastidal Parasites, in: Flohė, L., Jäger, T., Koch, O. (Eds.), Trypanosomatid Diseases: Molecular Routes to Drug Discovery. Wiley-VCH Verlag GmbH & Co. KGaA, pp. 405–428. doi:10.1002/9783527670383.ch22
Gissot, M., Walker, R., Delhaye, S., Alayi, T.D., Huot, L., Hot, D., Callebaut, I., Schaeffer-Reiss, C., Dorsselaer, A.V., Tomavo, S., (2013). Toxoplasma gondii Alba proteins are involved in translational control of gene expression. J Mol Biol [4.0] 425, 1287–301. doi:10.1016/j.jmb.2013.01.039
Guegan, F., Plazolles, N., Baltz, t., Coustou, V., (2013). Erythrophagocytosis of desialylated red blood cells is responsible for anaemia during Trypanosoma vivax infection. Cell Microbiol [4.8] 15, 1285–303. doi:10.1111/cmi.12123
Guizetti, J., Martins, R.M., Guadagnini, S., Claes, A., Scherf, A., (2013). Nuclear pores and perinuclear expression sites of var and ribosomal DNA genes correspond to physically distinct regions in Plasmodium falciparum. Eukaryot Cell [3.6] 12, 697–702. doi:10.1128/EC.00023-13
Guizetti, J., Scherf, A., (2013). Silence, activate, poise and switch! Mechanisms of antigenic variation in Plasmodium falciparum. Cell Microbiol [4.8] 15, 718–26. doi:10.1111/cmi.12115
Hon, C.C., Weber, C., Sismeiro, O., Proux, C., Koutero, M., Deloger, M., Das, S., Agrahari, M., Dillies, M.A., Jagla, B., Coppee, J.Y., Bhattacharya, A., Guillen, N., (2013). Quantification of stochastic noise of splicing and polyadenylation in Entamoeba histolytica. Nucleic Acids Res [8.8] 41, 1936–52. doi:10.1093/nar/gks1271
Jiang, L., Mu, J., Zhang, Q., Ni, T., Srinivasan, P., Rayavara, K., Yang, W., Turner, L., Lavstsen, T., Theander, T.G., Peng, W., Wei, G., Jing, Q., Wakabayashi, Y., Bansal, A., Luo, Y., Ribeiro, J.M., Scherf, A., Aravind, L., Zhu, J., Zhao, K., Miller, L.H., (2013). PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum. Nature [42.3] 499, 223–7. doi:10.1038/nature12361
Kong-Hap, M.A., Mouammine, A., Daher, W., Berry, L., Lebrun, M., Dubremetz, J.F., Besteiro, S., (2013). Regulation of ATG8 membrane association by ATG4 in the parasitic protist Toxoplasma gondii. Autophagy [11.4] 9, 1334–48. doi:10.4161/auto.25189
Lamacchia, M., Clayton, J.R., Wang-Sattler, R., Steinmetz, L.M., Levashina, E.A., Blandin, S.A., (2013). Silencing of Genes and Alleles by RNAi in Anopheles gambiae, in: Ménard, R. (Ed.), Malaria: Methods and Protocols, Methods in Molecular Biology. Humana Press, Totowa, NJ, pp. 161–176. doi:10.1007/978-1-62703-026-7_11
Maheshwari, S., Lavigne, M., Contet, A., Alberge, B., Pihan, E., Kocken, C., Wengelnik, K., Douguet, D., Vial, H., Cerdan, R., (2013). Biochemical characterization of Plasmodium falciparum CTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is active. Biochem J [4.7] 450, 159–67. doi:10.1042/BJ20121480
Mazet, M., Morand, P., Biran, M., Bouyssou, G., Courtois, P., Daulouede, S., Millerioux, Y., Franconi, J.M., Vincendeau, P., Moreau, P., Bringaud, F., (2013). Revisiting the central metabolism of the bloodstream forms of Trypanosoma brucei: production of acetate in the mitochondrion is essential for parasite viability. PLoS Negl Trop Dis [4.5] 7, e2587. doi:10.1371/journal.pntd.0002587
Millerioux, Y., Ebikeme, C., Biran, M., Morand, P., Bouyssou, G., Vincent, I.M., Mazet, M., Riviere, L., Franconi, J.M., Burchmore, R.J., Moreau, P., Barrett, M.P., Bringaud, F., (2013). The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control. Mol Microbiol [5.0] 90, 114–29. doi:10.1111/mmi.12351
Nagy, G.N., Marton, L., Kramos, B., Olah, J., Revesz, A., Vekey, K., Delsuc, F., Hunyadi-Gulyas, E., Medzihradszky, K.F., Lavigne, M., Vial, H., Cerdan, R., Vertessy, B.G., (2013). Evolutionary and mechanistic insights into substrate and product accommodation of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum. FEBS J [4.0] 280, 3132–48. doi:10.1111/febs.12282
Nzoumbou-Boko, R., Dethoua, M., Gabriel, F., Buguet, A., Cespuglio, R., Courtois, P., Daulouede, S., Bouteille, B., Ngampo, S., Mpandzou, G., Semballa, S., Vincendeau, P., (2013). Serum arginase, a biomarker of treatment efficacy in human African trypanosomiasis. J Clin Microbiol [4.2] 51, 2379–81. doi:10.1128/JCM.03371-12
Perdomo, D., Baron, B., Rojo-Dominguez, A., Raynal, B., England, P., Guillen, N., (2013). The alpha-helical regions of KERP1 are important in Entamoeba histolytica adherence to human cells. Sci Rep [5.1] 3, 1171. doi:10.1038/srep01171
Pied, S., (2013). The context of contanimation, in: International Innovation: Parasite of Poverty. pp. 83–85. http://www.internationalinnovation.com/parasites-of-poverty/
Pillay, D., Boulange, A.F., Coustou, V., Baltz, t., Coetzer, T.H., (2013a). Recombinant expression and biochemical characterisation of two alanyl aminopeptidases of Trypanosoma congolense. Exp Parasitol [1.9] 135, 675–84. doi:10.1016/j.exppara.2013.10.005
Pillay, D., Izotte, J., Fikru, R., Buscher, P., Mucache, H., Neves, L., Boulange, A., Seck, M.T., Bouyer, J., Napier, G.B., Chevtzoff, C., Coustou, V., Baltz, t., (2013b). Trypanosoma vivax GM6 antigen: a candidate antigen for diagnosis of African animal trypanosomosis in cattle. PLoS One [3.5] 8, e78565. doi:10.1371/journal.pone.0078565
Sen, P., Vial, H.J., Radulescu, O., (2013). Kinetic modelling of phospholipid synthesis in Plasmodium knowlesi unravels crucial steps and relative importance of multiple pathways. BMC Syst Biol [2.9] 7, 123. doi:10.1186/1752-0509-7-123
Sterkers, Y., Lachaud, L., Bourgeois, N., Crobu, L., Pagès, M., Bastien, P., (2013). Genome architecture and dynamics in the protozoan parasite Leishmania, in: López-Camarillo, C., Marchat, L.A. (Eds.), Comparative Genomics in Neglected Human Parasites. Nova Science Publishers Inc, New York, pp. 81–100. https://www.novapublishers.com/catalog/product_info.php?products_id=42893
Thibeaux, R., Weber, C., Hon, C.C., Dillies, M.A., Ave, P., Coppee, J.Y., Labruyere, E., Guillen, N., (2013). Identification of the virulence landscape essential for Entamoeba histolytica invasion of the human colon. PLoS Pathog [8.1] 9, e1003824. doi:10.1371/journal.ppat.1003824
Tomavo, S., Slomianny, C., Meissner, M., Carruthers, V.B., (2013). Protein trafficking through the endosomal system prepares intracellular parasites for a home invasion. PLoS Pathog [8.1] 9, e1003629. doi:10.1371/journal.ppat.1003629
Tomlins, A.M., Ben-Rached, F., Williams, R.A., Proto, W.R., Coppens, I., Ruch, U., Gilberger, T.W., Coombs, G.H., Mottram, J.C., Muller, S., Langsley, G., (2013). Plasmodium falciparum ATG8 implicated in both autophagy and apicoplast formation. Autophagy [11.4] 9, 1540–52. doi:10.4161/auto.25832
Walker, R., Gissot, M., Croken, M.M., Huot, L., Hot, D., Kim, K., Tomavo, S., (2013a). The Toxoplasma nuclear factor TgAP2XI-4 controls bradyzoite gene expression and cyst formation. Mol Microbiol [5.0] 87, 641–55. doi:10.1111/mmi.12121
Walker, R., Gissot, M., Huot, L., Alayi, T.D., Hot, D., Marot, G., Schaeffer-Reiss, C., Van Dorsselaer, A., Kim, K., Tomavo, S., (2013b). Toxoplasma transcription factor TgAP2XI-5 regulates the expression of genes involved in parasite virulence and host invasion. J Biol Chem [4.6] 288, 31127–38. doi:10.1074/jbc.M113.486589
Blank, O., Davioud-Charvet, E., Elhabiri, M., (2012). Interactions of the antimalarial drug methylene blue with methemoglobin and heme targets in Plasmodium falciparum: a physico-biochemical study. Antioxid Redox Signal [7.7] 17, 544–54. doi:10.1089/ars.2011.4239
Caldarelli, S.A., Hamel, M., Duckert, J.F., Ouattara, M., Calas, M., Maynadier, M., Wein, S., Perigaud, C., Pellet, A., Vial, H.J., Peyrottes, S., (2012). Disulfide prodrugs of albitiazolium (T3/SAR97276): synthesis and biological activities. J Med Chem [5.3] 55, 4619–28. doi:10.1021/jm3000328
Camara, D., Bisanz, C., Barette, C., Van Daele, J., Human, E., Barnard, B., Van der Straeten, D., Stove, C.P., Lambert, W.E., Douce, R., Marechal, E., Birkholtz, L.M., Cesbron-Delauw, M.F., Dumas, R., Rebeille, F., (2012). Inhibition of p-aminobenzoate and folate syntheses in plants and apicomplexan parasites by natural product rubreserine. J Biol Chem [4.6] 287, 22367–76. doi:10.1074/jbc.M112.365833
Coustou, V., Plazolles, N., Guegan, F., Baltz, t., (2012). Sialidases play a key role in infection and anaemia in Trypanosoma congolense animal trypanosomiasis. Cell Microbiol [4.8] 14, 431–45. doi:10.1111/j.1462-5822.2011.01730.x
Dacheux, D., Landrein, N., Thonnus, M., Gilbert, G., Sahin, A., Wodrich, H., Robinson, D.R., Bonhivers, M., (2012). A MAP6-related protein is present in protozoa and is involved in flagellum motility. PLoS One [3.5] 7, e31344. doi:10.1371/journal.pone.0031344
Degardin, M., Wein, S., Gouni, S., Tran Van Ba, C., Duckert, J.F., Durand, T., Escale, R., Vial, H., Vo-Hoang, Y., (2012). Evaluation of bis-alkylamidoxime O-alkylsulfonates as orally available antimalarials. ChemMedChem [3.2] 7, 991–1001. doi:10.1002/cmdc.201200112
Duarte, J., Herbert, F., Guiyedi, V., Franetich, J.F., Roland, J., Cazenave, P.A., Mazier, D., Kombila, M., Fesel, C., Pied, S., (2012). High levels of immunoglobulin E autoantibody to 14-3-3 epsilon protein correlate with protection against severe Plasmodium falciparum malaria. J Infect Dis [6.0] 206, 1781–9. doi:10.1093/infdis/jis595
Faust, D.M., Guillen, N., (2012). Virulence and virulence factors in Entamoeba histolytica, the agent of human amoebiasis. Microbes Infect [2.7] 14, 1428–41. doi:10.1016/j.micinf.2012.05.013
Gendron, T., Davioud-Charvet, E., Müller, T.J.J., (2012). Versatile Synthesis of Dissymmetric Diarylideneacetones via a Palladium-Catalyzed Coupling–Isomerization Reaction. Synthesis [2.4] 44, 3829–3835. doi:10.1055/s-0032-1316811
Gissot, M., Walker, R., Delhaye, S., Huot, L., Hot, D., Tomavo, S., (2012). Toxoplasma gondii chromodomain protein 1 binds to heterochromatin and colocalises with centromeres and telomeres at the nuclear periphery. PLoS One [3.5] 7, e32671. doi:10.1371/journal.pone.0032671
Hester, J., Mullins, J., Sa, Q., Payne, L., Mercier, C., Cesbron-Delauw, M.F., Suzuki, Y., (2012). Toxoplasma gondii antigens recognized by IgG antibodies differ between mice with and without active proliferation of tachyzoites in the brain during the chronic stage of infection. Infect Immun [4.2] 80, 3611–20. doi:10.1128/IAI.00604-12
Johann, L., Lanfranchi, D.A., Davioud-Charvet, E., Elhabiri, M., (2012). A physico-biochemical study on potential redox-cyclers as antimalarial and anti-schistosomal drugs. Curr Pharm Des [3.3] 18, 3539–66. doi:10.2174/138161212801327284
Joice, A.C., Lyda, T.L., Sayce, A.C., Verplaetse, E., Morris, M.T., Michels, P.A., Robinson, D.R., Morris, J.C., (2012). Extra-glycosomal localisation of Trypanosoma brucei hexokinase 2. Int J Parasitol [3.4] 42, 401–9. doi:10.1016/j.ijpara.2012.02.008
Lanfranchi, D.A., Belorgey, D., Muller, T., Vezin, H., Lanzer, M., Davioud-Charvet, E., (2012a). Exploring the trifluoromenadione core as a template to design antimalarial redox-active agents interacting with glutathione reductase. Org Biomol Chem [3.5] 10, 4795–806. doi:10.1039/c2ob25229e
Lanfranchi, D.A., Cesar-Rodo, E., Bertrand, B., Huang, H.H., Day, L., Johann, L., Elhabiri, M., Becker, K., Williams, D.L., Davioud-Charvet, E., (2012b). Synthesis and biological evaluation of 1,4-naphthoquinones and quinoline-5,8-diones as antimalarial and schistosomicidal agents. Org Biomol Chem [3.5] 10, 6375–87. doi:10.1039/c2ob25812a
May, S.F., Peacock, L., Almeida Costa, C.I., Gibson, W.C., Tetley, L., Robinson, D.R., Hammarton, T.C., (2012). The Trypanosoma brucei AIR9-like protein is cytoskeleton-associated and is required for nucleus positioning and accurate cleavage furrow placement. Mol Microbiol [5.0] 84, 77–92. doi:10.1111/j.1365-2958.2012.08008.x
Mercier, C., Cesbron-Delauw, M.-F., (2012). Safe living within a parasitophorous vacuole: The recipe of success by Toxoplasma gondii, in: Eric Ghigo, G.M.J.-L.M. (Ed.), Host-Pathogen Interaction: At the Frontier of Cellular Microbiology. Transworld Res. Network, Kerala, India. Research SignPost Publisher, pp. 217–250. http://www.ressign.com/UserArticleDetails.aspx?arid=11280
Millerioux, Y., Morand, P., Biran, M., Mazet, M., Moreau, P., Wargnies, M., Ebikeme, C., Deramchia, K., Gales, L., Portais, J.C., Boshart, M., Franconi, J.M., Bringaud, F., (2012). ATP synthesis-coupled and -uncoupled acetate production from acetyl-CoA by mitochondrial acetate:succinate CoA-transferase and acetyl-CoA thioesterase in Trypanosoma. J Biol Chem [4.6] 287, 17186–97. doi:10.1074/jbc.M112.355404
Persat, F., Mercier, C., Ficheux, D., Colomb, E., Trouillet, S., Bendridi, N., Musset, K., Loeuillet, C., Cesbron-Delauw, M.F., Vincent, C., (2012). A synthetic peptide derived from the parasite Toxoplasma gondii triggers human dendritic cells’ migration. J Leukoc Biol [4.3] 92, 1241–50. doi:10.1189/jlb.1211600
Peyrottes, S., Caldarelli, S., Wein, S., Perigaud, C., Pellet, A., Vial, H., (2012). Choline analogues in malaria chemotherapy. Curr Pharm Des [3.3] 18, 3454–66. doi:10.2174/138161212801327338
Sloves, P.J., Delhaye, S., Mouveaux, T., Werkmeister, E., Slomianny, C., Hovasse, A., Dilezitoko Alayi, T., Callebaut, I., Gaji, R.Y., Schaeffer-Reiss, C., Van Dorsselear, A., Carruthers, V.B., Tomavo, S., (2012). Toxoplasma sortilin-like receptor regulates protein transport and is essential for apical secretory organelle biogenesis and host infection. Cell Host Microbe [13.6] 11, 515–27. doi:10.1016/j.chom.2012.03.006
Teixeira, P.C., Frade, A.F., Nogueira, L.G., Kalil, J., Chevillard, C., Cunha-Neto, E., (2012). Pathogenesis of Chagas disease cardiomyopathy. World J Clin Infect Dis [no IF] 2, 39–53. doi:10.5495/wjcid.v2.i3.39
Vo Duy, S., Besteiro, S., Berry, L., Perigaud, C., Bressolle, F., Vial, H.J., Lefebvre-Tournier, I., (2012). A quantitative liquid chromatography tandem mass spectrometry method for metabolomic analysis of Plasmodium falciparum lipid related metabolites. Anal Chim Acta [4.6] 739, 47–55. doi:10.1016/j.aca.2012.06.016
Wein, S., Maynadier, M., Bordat, Y., Perez, J., Maheshwari, S., Bette-Bobillo, P., Tran Van Ba, C., Penarete-Vargas, D., Fraisse, L., Cerdan, R., Vial, H., (2012). Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate. Br J Pharmacol [4.5] 166, 2263–76. doi:10.1111/j.1476-5381.2012.01966.x
Postdoctoral position, Institut Pasteur, Paris, France A 24-month post-doctoral position starting on March 1st 2025 and funded by the French National Research Agency (ANR) is available in the Trypanosome...
Postdoctoral positions, LPHI Lab, Montpellier, France Two ERC-funded (JANUS 2024-2029) postdoc positions are open in the lab to study cell cycle regulation in malaria...
Postdoctoral position, Institut Pasteur, Paris, France A postdoc position is available at the Institut Pasteur Paris, in the signalling and host-parasite interactions research group, headed by Dr Najma Rachidi...
ABOUT SPEAKERS PROGRAMME REGISTRATION CONTACT LOCATION About the workshop ParaFrap organise pour la première fois en 2024 le ParaFrap Next...
[Communiqué] Dans le cadre des actions du Plan innovation Santé 2030, le volet santé du plan France 2030, Mohamed-Ali Hakimi est l'un des 22 lauréats d'une Chaire d’excellence en Biologie / Santé, soutenus pour mener des projets de...
The York Biomedical Research Institute (YBRI) are hosting an online live seminar on Friday 24th May 1-2pm BST as part of their biomedical science seminar series. You are all welcome to attend - registration is required via the...
[Communiqué] Félicitations à Arthur Talman, chargé de recherche IRD dans le laboratoire MIVEGEC (Montpellier), qui a obtenu une subvention "Advanced Grant" du Conseil européen de la recherche (ERC) pour le projet "TROJAN -...
Ana Rita Gomes, chargée de recherche CNRS au Laboratoire des Pathogènes et de l'Immunité de l'Hôte à Montpellier, et ancienne Postdoc du LabEx ParaFrap, a été récompensée par la prestigieuse Médaille de Bronze...
Bonnes années 2024 ! Pour bien commencer cette nouvelle année scientifique, voici le programme des webinaires ParaFrap. Depuis Janvier 2021, ParaFrap organise une série de webinaires. Ce rendez-vous mensuel, organisé tous les 2ème jeudi du...
L'équipe du Dr. Mohamed-Ali Hakimi, en collaboration avec Isabelle Coppens (Johns Hopkins University Bloomberg School of Public Health and Malaria Research Institute, Baltimore, MD, USA), a développé une nouvelle méthode (épi)génétique...
Actualités du LabEx
Autres actualités
Project Manager: Yoann MILLERIOUX
Contact
@ParaFrap #ParaFrap |
© 2023. Tous droits réservés by MLCOM
Notre site LabEx ParaFrap utilise des cookies pour réaliser des statistiques de visites, partager des contenus sur les réseaux sociaux et améliorer votre expérience. En refusant les cookies, certains services seront amenés à ne pas fonctionner correctement. Nous conservons votre choix pendant 30 jours. Vous pouvez changer d'avis en cliquant sur le bouton 'Cookies' en bas à gauche de chaque page de notre site. En savoir plus
Ce site utilise des cookies pour assurer son bon fonctionnement et ne peuvent pas être désactivés de nos systèmes. Nous ne les utilisons pas à des fins publicitaires. Si ces cookies sont bloqués, certaines parties du site ne pourront pas fonctionner.
Ce site utilise des cookies de mesure et d’analyse d’audience, tels que Google Analytics et Google Ads, afin d’évaluer et d’améliorer notre site internet.
Ce site utilise des composants tiers, tels que NotAllowedScript675c211be94eeReCAPTCHA, Google NotAllowedScript675c211be80abMaps, MailChimp ou Calameo, qui peuvent déposer des cookies sur votre machine. Si vous décider de bloquer un composant, le contenu ne s’affichera pas
Des plug-ins de réseaux sociaux et de vidéos, qui exploitent des cookies, sont présents sur ce site web. Ils permettent d’améliorer la convivialité et la promotion du site grâce à différentes interactions sociales.
Ce site web utilise un certain nombre de cookies pour gérer, par exemple, les sessions utilisateurs.