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Alliance Française contre les Maladies Parasitaires



Project Title : "Characterization of P. falciparum histone methyl transferases: biological role and possible targets for new intervention strategies"

Project PI : Artur Scherf Co-PI : Dominique Mazier

Thesis defense : 15/12/2016  thesesfr

Lab : Biology of Host-parasite Interactions, Pasteur Institute, Paris



Postdoctoral researcher in Artur Scherf Lab, Pasteur Institute, Paris - France


Demarta-Gatsi, C., Rivkin, A., Di Bartolo, V., Peronet, R., Ding, S., Commere, P.-H., Guillonneau, F., Bellalou, J., Brûlé, S., Abou Karam, P., Cohen, S.R., Lagache, T., Janse, C.J., Regev-Rudzki, N., Mécheri, S., (2019). Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses. Cell Microbiol [4.4] 0, e13021. doi: 10.1111/cmi.13021

Zanghi, G., S. S. Vembar, S. Baumgarten, S. Ding, J. Guizetti, J. M. Bryant, D. Mattei, A. T. R. Jensen, L. Renia, Y. S. Goh, R. Sauerwein, C. C. Hermsen, J. F. Franetich, M. Bordessoulles, O. Silvie, V. Soulard, O. Scatton, P. Chen, S. Mecheri, D. Mazier and A. Scherf (2018). "A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection." Cell Rep [8.3] 22(11): 2951-2963. [Pubmed]

Sindikubwabo, F., S. Ding, T. Hussain, P. Ortet, M. Barakat, S. Baumgarten, D. Cannella, A. Palencia, A. Bougdour, L. Belmudes, Y. Coute, I. Tardieux, C. Y. Botte, A. Scherf and M. A. Hakimi (2017). "Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites." eLife [7.7] 6. [Pubmed] [PDF]

Chen, P. B., S. Ding, G. Zanghi, V. Soulard, P. A. DiMaggio, M. J. Fuchter, S. Mecheri, D. Mazier, A. Scherf and N. A. Malmquist (2016). "Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites." Sci Rep [5.2] 6: 21802. [Pubmed] [PDF]