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Alliance Française contre les Maladies Parasitaires

Home PhD 1ère vague Fabien Sindikubwabo

Fabien Sindikubwabo

Sindikubwabo

Project Title : "Subversion of the host cell epigenome following infection by Toxoplasma gondii and Theileria annulata"

Project PI : Mohamed-Ali Hakimi Co-PI : Gordon Langsley

Thesis defense : 12/10/2017  thesesfr

Lab : Host-pathogen interactions & Immunity to infections, IAB, Grenoble

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BACKGROUND

  • Certificate, training on business companies, University Grenoble-Alpes - France (2014-2016)
  • Master's degree in Génie génétique et biochimie, University Toulouse III - France (2012-2013)
  • Master's degree in Génie biotechnologique parcours biochimie, University of La Rochelle - France (2010-2012)

POSITION AFTER PARAFRAP TRAINING

  • Since 2020: CNRS Researcher (CRCN-permanent) in Raphaël Rodriguez Lab, Chemical biology of cancer, Institue Curie, Paris - France
  • 2016-2020: Postdoctoral researcher in Raphaël Rodriguez Lab, Chemical biology of cancer, Institue Curie, Paris - France 

PUBLICATIONS

Sindikubwabo, F., S. Ding, T. Hussain, P. Ortet, M. Barakat, S. Baumgarten, D. Cannella, A. Palencia, A. Bougdour, L. Belmudes, Y. Coute, I. Tardieux, C. Y. Botte, A. Scherf and M. A. Hakimi (2017). "Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites." eLife [7.7] 6. [Pubmed] [PDF]

Venugopal, K., E. Werkmeister, N. Barois, J. M. Saliou, A. Poncet, L. Huot, F. Sindikubwabo, M. A. Hakimi, G. Langsley, F. Lafont and S. Marion (2017). "Dual role of the Toxoplasma gondii clathrin adaptor AP1 in the sorting of rhoptry and microneme proteins and in parasite division." PLoS Pathog [7.0] 13(4): e1006331. [Pubmed] [PDF]

Sakura, T., F. Sindikubwabo, L. K. Oesterlin, H. Bousquet, C. Slomianny, M. A. Hakimi, G. Langsley and S. Tomavo (2016). "A Critical Role for Toxoplasma gondii Vacuolar Protein Sorting VPS9 in Secretory Organelle Biogenesis and Host Infection." Sci Rep [5.2] 6: 38842. [Pubmed] [PDF]

Sangare, L. O., T. D. Alayi, B. Westermann, A. Hovasse, F. Sindikubwabo, I. Callebaut, E. Werkmeister, F. Lafont, C. Slomianny, M. A. Hakimi, A. Van Dorsselaer, C. Schaeffer-Reiss and S. Tomavo (2016). "Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection." Nat Commun [11.3] 7: 11191. [Pubmed] [PDF]