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Alliance Française contre les Maladies Parasitaires

Home EMPLOIS PhD Opportunity | African Trypanosomes | University of York

PhD Opportunity | African Trypanosomes | University of York

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Multidisciplinary PhD opportunity in the fields of
infectious diseases, gene regulations and molecular signalisation.

 

 Fully Funded 4-Year PhD at the University of York 

A fully funded PhD opportunity is available at the University of York through the Medical Research Council (MRC) DiMeN Doctoral Training Partnership (DTP).
This multidisciplinary project brings together the fields of infectious diseases, gene regulation, and molecular signalisation.

 Research Focus 

Join the University of York to investigate the biology of African Trypanosomes (Trypanosoma brucei) — parasites responsible for Sleeping Sickness and Nagana, which together cost the global economy more than $4.5 billion each year.

This project sits at the intersection of molecular biology and infection research.
T. brucei depends heavily on post-transcriptional gene regulation for its survival and life cycle progression, as it lacks extensive transcriptional control.

 Project Goal 

You will use cutting-edge technology to study the diversity, architecture, and regulation of biomolecular condensates, essential membraneless organelles.
 Recent findings suggest that these condensates play a key role in the parasite’s adaptability and transmission to diverse hosts.

 Why Apply 

  • Gain expertise in molecular mechanisms and advanced technologies such as:

    • Kinome-wide RNAi library and CRISPR-mediated single-point mutagenesis

    • Volumetric electron microscopy

    • Next-Generation Sequencing (NGS)

  • Join a vibrant research environment at the University of York and the York Biomedical Research Institute.

  • Work under the supervision of Dr. Mathieu Cayla and Dr. Pegine Walrad.

  • Become part of a diverse community of PhD students across the North of England (Universities of Leeds, Liverpool, Newcastle, York, and Sheffield) researching major global health challenges.

  • Fully funded for 4 years through the MRC DiMeN DTP, covering tuition fees, annual stipend, and project costs.

 Application Information 

Application Deadline: 4th December 2025

Applications must be submitted via the DiMeN website:
👉 www.dimen.org.uk

For full details, see the advert on Find A PhD:
👉 Project Page on Find A PhD


📄 DiMeN_DTP_-_PhD_project.pdf

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