Registration for EMBO Workshop : Molecular advances and parasite strategies in host infection , supported by ParaFrap will open soon. Follow this link and enter your e-mail address to be notified when the website is launched http://urlz.fr/6zMr
Registration for EMBO Workshop : Molecular advances and parasite strategies in host infection , supported by ParaFrap will open soon. Follow this link and enter your e-mail address to be notified when the website is launched http://urlz.fr/6zMr
ParaFrap supports the organization of the EMBO Workshop: Molecular advances and parasite strategies in host infection, from September 30 to October 3, 2018 on Les Embiez Island (south of France). The 2018 workshop, supported by EMBO, is to bring together the international experts in Parasitology to understand how parasite survival mechanisms are controlled, developed and organized.
More details coming soon ...
Follow this link and enter your e-mail address to be notified when the website is launched http://urlz.fr/6zMr
The 2nd ParaFrap bioinformatics workshop starts this week in Montpellier. This workshop is organized by Prof. Patrick Bastien, Scientific Coordinator and Coordinator of the ParaFrap Doctoral Program, and Prof. David Roos of the Eukaryotic Pathogens DataBase 'EuPathDB' team, internationally renowned for the quality of its training sessions on bioinformatics tools.
The workshop program is available here : 2nd_ParaFrap_Bioinfo_Workshop_2017
Follow the news of the workshop on twitter :
Molecules that target both malaria infection and transmission ... Because they are linked to a steroid, new molecules derived from ortho-aminocresols, already known for their antimalarial action, prove to be more effective in killing the parasite in the infected host, but also to block its transmission. This work, published in Nature Communications, is the result of a multidisciplinary and international collaboration led by German researchers (universities of Jena and Giessen) and French members of ParaFrap (Elisabeth Davioud-Charvet - Molecular Chemistry Laboratory, Institute of Biology Molecular and cellular CNRS with the collaboration of the laboratory of Stéphanie Blandin - Inserm "Immune response in the Anopheles mosquito vector of malaria" of Strasbourg). This work shows that for their survival, the parasites responsible for malaria and toxoplasmosis depend on mechanisms inherited from the plant world. This discovery represents a major advance in the development of new therapeutic targets against these parasites with major public health consequences.
This work has been the subject of numerous press releases, which you can find HERE.
Référence :
Arylmethylamino steroids as antiparasitic agents. Krieg, R., E. Jortzik, A. A. Goetz, S. Blandin, S. Wittlin, M. Elhabiri, M. Rahbari, S. Nuryyeva, K. Voigt, H. M. Dahse, A. Brakhage, S. Beckmann, T. Quack, C. G. Grevelding, A. B. Pinkerton, B. Schonecker, J. Burrows, E. Davioud-Charvet, S. Rahlfs and K. Becker (2017). Nat Commun 8: 14478. Link
Plasmodium falciparum and Toxoplasma are mandatory intracellular parasites, which represent a major threat to global health. They infect hundreds of millions people every year, leading to high mortality, especially among children. An international team coordinated by Mohamed-Ali Hakimi, a ParaFrap member at the Institute for the Advancement of Biosciences, and including researchers from EMBL-Grenoble and ANACOR pharmaceutical, has discovered a new molecule, AN3661, which stops the proliferation of parasites. The molecule allows a complete cure of mice infected with Toxoplasma. This study was published on February, 1, 2017 in EMBO Molecular Medicine journal. This work has been the subject of numerous press releases, which you can find HERE (French).
Référence :
Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis. Palencia, A., A. Bougdour, M. P. Brenier-Pinchart, B. Touquet, R. L. Bertini, C. Sensi, G. Gay, J. Vollaire, V. Josserand, E. Easom, Y. R. Freund, H. Pelloux, P. J. Rosenthal, S. Cusack and M. A. Hakimi (2017). EMBO Mol Med [9.5]. Link
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[Communiqué] As part of the actions of the Health Innovation Plan 2030, the health component of the France 2030 plan, Mohamed-Ali Hakimi is one of the 22 laureates of an Excellence Chair in Biology/Health, supported to conduct high-level research...
The York Biomedical Research Institute (YBRI) are hosting an online live seminar on Friday 24th May 1-2pm BST as part of their biomedical science seminar series. You are all welcome to attend - registration is required via the...
[Communiqué] Congratulations to Arthur Talman, IRD Research Leader in the MIVEGEC laboratory (Montpellier), who has been awarded an Advanced Grant from the European Research Council (ERC) for the project "TROJAN - Molecular mimicry and immune...
Ana Rita Gomes, a CNRS Research Associate at the Laboratory of Pathogens and Host Immunity in Montpellier, and former Postdoctoral fellow of the LabEx ParaFrap, has been awarded the prestigious CNRS Bronze Medal in 2023. This...
. PhD Opportunity, Tours, France Supervision Thesis Supervisor: Sonia LAMANDE; Co-Supervisor: Julie TOTTEY Project: FUNTIONAL CHARACTERISATION OF CYSTEINE CATHEPSINS IN THE APICOMPLEXAN PARASITE CRYPTOSPORIDIUM...
Senior PostDoc position : computational biologist, Paris, France The ParSig team (https://research.pasteur.fr/en/team/molecular-parasitology-and-signaling) at the Institut Pasteur in Paris seeks for a highly...
Researcher in Livestock Immunology for the Study of Animal Trypanosomoses Through a One Health approach, the Intertryp Joint Research Unit (Cirad-IRD) is developing research on interactions between hosts,...
Happy New Year 2024! To kick off this new scientific year, here is the ParaFrap webinar schedule. Since January 2021, ParaFrap has been organizing a series of webinars. This monthly event, held every 2nd Thursday of the month, aims to strengthen...
PostDoc position : functional analysis of P. falciparum early gametocyte proteins, Allschwil, Switzerland The Malaria Gene Regulation Lab of Till Voss is looking for a highly motivated and talented postdoc to...
The team of Dr. Mohamed-Ali Hakimi, in collaboration with Isabelle Coppens (Johns Hopkins University Bloomberg School of Public Health and Malaria Research Institute, Baltimore, MD, USA), has developed a new (epi)genetic method to produce in vitro...
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