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ABOUT
- Who are we
- Objectives of the LabEx
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- Industrial collaborators
- Institutional and Financial Supports
- GOVERNANCE
Press release - LCBM/Anopheles Teams
Molecules that target both malaria infection and transmission ... Because they are linked to a steroid, new molecules derived from ortho-aminocresols, already known for their antimalarial action, prove to be more effective in killing the parasite in the infected host, but also to block its transmission. This work, published in Nature Communications, is the result of a multidisciplinary and international collaboration led by German researchers (universities of Jena and Giessen) and French members of ParaFrap (Elisabeth Davioud-Charvet - Molecular Chemistry Laboratory, Institute of Biology Molecular and cellular CNRS with the collaboration of the laboratory of Stéphanie Blandin - Inserm "Immune response in the Anopheles mosquito vector of malaria" of Strasbourg). This work shows that for their survival, the parasites responsible for malaria and toxoplasmosis depend on mechanisms inherited from the plant world. This discovery represents a major advance in the development of new therapeutic targets against these parasites with major public health consequences.
This work has been the subject of numerous press releases, which you can find HERE.
Référence :
Arylmethylamino steroids as antiparasitic agents. Krieg, R., E. Jortzik, A. A. Goetz, S. Blandin, S. Wittlin, M. Elhabiri, M. Rahbari, S. Nuryyeva, K. Voigt, H. M. Dahse, A. Brakhage, S. Beckmann, T. Quack, C. G. Grevelding, A. B. Pinkerton, B. Schonecker, J. Burrows, E. Davioud-Charvet, S. Rahlfs and K. Becker (2017). Nat Commun 8: 14478. Link
Tuesday, 16 April 2024Seminar - Boris Striepen - May 24
The York Biomedical Research Institute (YBRI) are hosting an online live seminar on Friday 24th May 1-2pm BST as part of their biomedical science seminar series. You are all welcome to attend - registration is required via the...
Friday, 12 April 2024Arthur Talman received an ERC Advanced grant
[Communiqué] Congratulations to Arthur Talman, IRD Research Leader in the MIVEGEC laboratory (Montpellier), who has been awarded an Advanced Grant from the European Research Council (ERC) for the project "TROJAN - Molecular mimicry and immune...
Wednesday, 13 March 2024CNRS Bronze Medal for Ana Rita GOMES
Ana Rita Gomes, a CNRS Research Associate at the Laboratory of Pathogens and Host Immunity in Montpellier, and former Postdoctoral fellow of the LabEx ParaFrap, has been awarded the prestigious CNRS Bronze Medal in 2023. This...
Monday, 11 March 2024PhD Offer l Cryptosporidium l Tours
. PhD Opportunity, Tours, France Supervision Thesis Supervisor: Sonia LAMANDE; Co-Supervisor: Julie TOTTEY Project: FUNTIONAL CHARACTERISATION OF CYSTEINE CATHEPSINS IN THE APICOMPLEXAN PARASITE CRYPTOSPORIDIUM...
Tuesday, 06 February 2024PostDoc l Computational Biologist l Paris, France
Senior PostDoc position : computational biologist, Paris, France The ParSig team (https://research.pasteur.fr/en/team/molecular-parasitology-and-signaling) at the Institut Pasteur in Paris seeks for a highly...
Monday, 22 January 2024Researcher l Immunology l Montpellier, France
Researcher in Livestock Immunology for the Study of Animal Trypanosomoses Through a One Health approach, the Intertryp Joint Research Unit (Cirad-IRD) is developing research on interactions between hosts,...
Sunday, 07 January 2024Webinars 2024
Happy New Year 2024! To kick off this new scientific year, here is the ParaFrap webinar schedule. Since January 2021, ParaFrap has been organizing a series of webinars. This monthly event, held every 2nd Thursday of the month, aims to strengthen...
Wednesday, 20 December 2023PostDoc l Plasmodium l Allschwil, Switzerland
PostDoc position : functional analysis of P. falciparum early gametocyte proteins, Allschwil, Switzerland The Malaria Gene Regulation Lab of Till Voss is looking for a highly motivated and talented postdoc to...
Wednesday, 13 December 2023New method to produce in vitro Toxoplasma pre-gametes
The team of Dr. Mohamed-Ali Hakimi, in collaboration with Isabelle Coppens (Johns Hopkins University Bloomberg School of Public Health and Malaria Research Institute, Baltimore, MD, USA), has developed a new (epi)genetic method to produce in vitro...
Friday, 06 October 2023Success for ParaFrap at MPM2023
Success for ParaFrap students at MPM2023 Parafrap students won numerous awards at the MPM 2023, Woods Hole USA, 17-21 September 2023. A warm congratulations to all ! Parul Sharma (2nd year PhD under the...
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